Immune Activation in Irritable Bowel Syndrome: Can Neuroimmune Interactions Explain Symptoms?

Lower Serum IL-10 Is an Independent Predictor of IBS Among Volunteers in Mexico

(2012) Max Schmulson et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mucosal Immune Cell Numbers and Visceral Sensitivity in Patients With Irritable Bowel Syndrome: Is There Any Relationship?

(2012) Breg Braak et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Jejunum of Diarrhea-Predominant Irritable Bowel Syndrome Shows Molecular Alterations in the Tight Junction Signaling Pathway That Are Associated With Mucosal Pathobiology and Clinical Manifestations

(2012) Cristina Martínez et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Helper T cell diversity and plasticity

(2012) Shingo Nakayamada et al.   CURRENT OPINION IN IMMUNOLOGY

Cytokine gene polymorphisms are associated with irritable bowel syndrome: a systematic review and meta-analysis

(2012) M. Bashashati et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Anti-Enteric Neuronal Antibodies and the Irritable Bowel Syndrome

(2012) Jackie D Wood et al.   Journal of Neurogastroenterology and Motility

Altered peripheral toll-like receptor responses in the irritable bowel syndrome

(2011) D. P. McKernan et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome

(2011) Lin Chang et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Combination of Allergic Factors Can Worsen Diarrheic Irritable Bowel Syndrome: Role of Barrier Defects and Mast Cells

(2011) M Vivinus-Nébot et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Intestinal Serotonin Release, Sensory Neuron Activation and Abdominal Pain in Irritable Bowel Syndrome

(2011) Cesare Cremon et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Expression and the Cellular Distribution of the Tight Junction Proteins Are Altered in Irritable Bowel Syndrome Patients With Differences According to the Disease Subtype

(2011) Nathalie Bertiaux-Vandaële et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Small Bowel Homing T Cells Are Associated With Symptoms and Delayed Gastric Emptying in Functional Dyspepsia

(2011) Tobias Liebregts et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Efficacy and Safety of Rifaximin for the Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis

(2011) Stacy B Menees et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Antibodies interfering with the type 3 muscarinic receptor pathway inhibit gastrointestinal motility and cholinergic neurotransmission in Sjögren's syndrome

(2011) Kyungpyo Park et al.   ARTHRITIS AND RHEUMATISM

Leaky Gut in Patients with Diarrhea-Predominant Irritable Bowel Syndrome and Inactive Ulcerative Colitis

(2011) Krisztina Gecse et al.   DIGESTION

Impaired Uptake of Serotonin by Platelets From Patients With Irritable Bowel Syndrome Correlates With Duodenal Immune Activation

(2011) Stephen Foley et al.   GASTROENTEROLOGY

Global and Deep Molecular Analysis of Microbiota Signatures in Fecal Samples From Patients With Irritable Bowel Syndrome

(2011) Mirjana Rajilić–Stojanović et al.   GASTROENTEROLOGY

Immune cell–derived opioids protect against neuropathic pain in mice

(2011) Dominika Labuz et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional gastrointestinal disorders in inflammatory bowel disease: Impact on quality of life and psychological status

(2011) Robert V. Bryant et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Rifaximin Therapy for Patients with Irritable Bowel Syndrome without Constipation

(2011) Mark Pimentel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Implications of eosinophilia in the normal duodenal biopsy - an association with allergy and functional dyspepsia

(2010) M. M. WALKER et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Plasma Cytokine Profiles in Females With Irritable Bowel Syndrome and Extra-Intestinal Co-Morbidity

(2010) Paul Scully et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Differential Expression of Toll-Like Receptors in Patients With Irritable Bowel Syndrome

(2010) Elizabeth K Brint et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons

(2010) Fernando Ochoa-Cortes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism

(2010) Dervla O'Malley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Chlamydia trachomatis antigens in enteroendocrine cells and macrophages of the small bowel in patients with severe irritable bowel syndrome

(2010) Aldona Dlugosz et al.   BMC GASTROENTEROLOGY

Abdominal pain in Irritable Bowel Syndrome: A review of putative psychological, neural and neuro-immune mechanisms

(2010) Sigrid Elsenbruch   BRAIN BEHAVIOR AND IMMUNITY

Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis

(2010) Alexandra–Chloé Villani et al.   GASTROENTEROLOGY

TNF  is a key mediator of the pronociceptive effects of mucosal supernatant from human ulcerative colitis on colonic DRG neurons

(2010) C. Ibeakanma et al.   GUT

The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome

(2010) T. K. Klooker et al.   GUT

Human visceral afferent recordings: preliminary report

(2010) M. Peiris et al.   GUT

'First-in-man': characterising the mechanosensitivity of human colonic afferents

(2010) W. Jiang et al.   GUT

T-Helper 1, T-Helper 2, and T-Regulatory Cytokines Gene Polymorphisms in Irritable Bowel Syndrome

(2010) Elham Barkhordari et al.   INFLAMMATION

Interleukin-17 Contributes to Neuroinflammation and Neuropathic Pain Following Peripheral Nerve Injury in Mice

(2010) Cristina Fabiola Kim et al.   JOURNAL OF PAIN

Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions

(2010) Lena Öhman et al.   Nature Reviews Gastroenterology & Hepatology

The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat

(2010) D. P Mckernan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Duodenal mastocytosis, eosinophilia and intraepithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia

(2009) M. M. WALKER et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mucosal Immune Activation in Irritable Bowel Syndrome: Gender-Dependence and Association With Digestive Symptoms

(2009) Cesare Cremon et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Increased Proteasome-Mediated Degradation of Occludin in Irritable Bowel Syndrome

(2009) Moïse Coëffier et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

T-Cell Activation in Patients With Irritable Bowel Syndrome

(2009) Lena Öhman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Elevated Human β-Defensin-2 Levels Indicate an Activation of the Innate Immune System in Patients With Irritable Bowel Syndrome

(2009) Jost Langhorst et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Post-inflammatory modification of colonic afferent mechanosensitivity

(2009) PA Hughes et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: Systematic Review and Meta-analysis

(2009) Alexander C. Ford et al.   Clinical Gastroenterology and Hepatology

A Molecular Analysis of Fecal and Mucosal Bacterial Communities in Irritable Bowel Syndrome

(2009) Caroline Codling et al.   DIGESTIVE DISEASES AND SCIENCES

Activation of Human Enteric Neurons by Supernatants of Colonic Biopsy Specimens From Patients With Irritable Bowel Syndrome

(2009) Sabine Buhner et al.   GASTROENTEROLOGY

Postinfectious Irritable Bowel Syndrome

(2009) Robin Spiller et al.   GASTROENTEROLOGY

TRPV1-expressing sensory fibres and IBS: links with immune function

(2009) P A Hughes et al.   GUT

Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses

(2009) P A Hughes et al.   GUT

MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome

(2009) Q. Zhou et al.   GUT

Proinflammatory Cytokine Gene Polymorphisms in Irritable Bowel Syndrome

(2009) Elham Barkhordari et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

(2009) Nicola Eastaff-Leung et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The Endogenous Hydrogen Sulfide Producing Enzyme Cystathionine-β Synthase Contributes to Visceral Hypersensitivity in a Rat Model of Irritable Bowel Syndrome

(2009) Guang-Yin Xu et al.   Molecular Pain

The role of TLRs, NLRs and RLRs in mucosal innate immunity and homeostasis

(2009) E C Lavelle et al.   Mucosal Immunology

Synergy of IL-23 and Th17 Cytokines: New Light on Inflammatory Bowel Disease

(2009) Wei Shen et al.   NEUROCHEMICAL RESEARCH

B-cell activation in patients with irritable bowel syndrome (IBS)

(2009) l. öhman et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Prolonged IL-1β exposure alters neurotransmitter and electrically induced Ca2+responses in the myenteric plexus

(2009) s. kindt et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome

(2009) QiQi Zhou et al.   PAIN

Fecal proteases from diarrheic-IBS and ulcerative colitis patients exert opposite effect on visceral sensitivity in mice

(2009) Anita Annaházi et al.   PAIN

Opioid receptors in the gastrointestinal tract

(2009) Peter Holzer   REGULATORY PEPTIDES

Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome

(2008) J. ZENG et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel disease

(2008) A. A. MIKOCKA-WALUS et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Enhanced Cholinergic-Mediated Increase in the Pro-Inflammatory Cytokine IL-6 in Irritable Bowel Syndrome: Role of Muscarinic Receptors

(2008) Timothy G. Dinan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Alterations in Mucosal Immunity Identified in the Colon of Patients With Irritable Bowel Syndrome

(2008) Jeroen Aerssens et al.   Clinical Gastroenterology and Hepatology

Probiotics in functional gastrointestinal disorders: what are the facts?

(2008) E QUIGLEY   CURRENT OPINION IN PHARMACOLOGY

Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators

(2008) T Piche et al.   GUT

Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity

(2008) K. Gecse et al.   GUT

Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain

(2008) A Akbar et al.   GUT

The gaseous mediator, hydrogen sulphide, inhibitsin vitromotor patterns in the human, rat and mouse colon and jejunum

(2008) d. gallego et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Trypsinogen IV, serotonin transporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients

(2008) a. p. m. kerckhoffs et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Antibodies to flagellin indicate reactivity to bacterial antigens in IBS patients

(2008) a. m. schoepfer et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Immune dysfunction in patients with functional gastrointestinal disorders

(2008) s. kindt et al.   NEUROGASTROENTEROLOGY AND MOTILITY

A pilot study of colonic B cell pattern in irritable bowel syndrome

(2008) Johan Forshammar et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Mucosal cytokine imbalance in irritable bowel syndrome

(2008) John Macsharry et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY