A 12-Week, Randomized, Controlled Trial With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Linaclotide in Irritable Bowel Syndrome With Constipation

Characteristics of Acute Pain Attacks in Patients With Irritable Bowel Syndrome Meeting Rome III Criteria

(2011) Per M Hellström et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Two Randomized Trials of Linaclotide for Chronic Constipation

(2011) Anthony J. Lembo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Linaclotide Improves Abdominal Pain and Bowel Habits in a Phase IIb Study of Patients With Irritable Bowel Syndrome With Constipation

(2010) Jeffrey M. Johnston et al.   GASTROENTEROLOGY

Measuring irritable bowel syndrome patient-reported outcomes with an abdominal pain numeric rating scale

(2009) B. SPIEGEL et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

An Evidence-Based Position Statement on the Management of Irritable Bowel Syndrome

(2009)   AMERICAN JOURNAL OF GASTROENTEROLOGY

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain

(2009) h. eutamene et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome - results of two randomized, placebo-controlled studies

(2008) D. A. DROSSMAN et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Irritable Bowel Syndrome

(2008) Emeran A. Mayer   NEW ENGLAND JOURNAL OF MEDICINE