Article
Gastroenterology & Hepatology
Zhao -Chao Zhang, Jia-Qi Xu, Xin-Yang Liu, Hai-Ting Pan, Shi-Yao Chen, Yun-Shi Zhong, Yi-Qun Zhang, Wei-Feng Chen, Li -Li Ma, Jian-Wei Hu, Ming-Yan Cai, Wen-Zheng Qin, Quan-Lin Li, Ping-Hong Zhou
Summary: Salvage POEM is a promising treatment option for achalasia patients who have experienced myotomy failure, especially after a previous POEM failure, as it has a high rate of treatment success and clinical relief.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Pamela Milito, Stefano Siboni, Andrea Lovece, Erika Andreatta, Emanuele Asti, Luigi Bonavina
Summary: Revisional therapy for esophageal achalasia after failed Heller myotomy is feasible, safe, and effective in specialized and multidisciplinary centers. Following revisional therapy, patients experienced a significant improvement in symptoms with a low overall complication rate.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Review
Surgery
Rebecca C. Dirks, Geoffrey P. Kohn, Bethany Slater, Jake Whiteside, Noe A. Rodriguez, Salvatore Docimo, Aurora Pryor, Dimitrios Stefanidis
Summary: POEM has similar outcomes to HM and greater efficacy than PD. Reflux remains a critical outcome with unknown long-term clinical significance due to insufficient data and inconsistent reporting.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Caroline M. G. Saleh, Pietro Familiari, Barbara A. J. Bastiaansen, Paul Fockens, Jan Tack, Guy Boeckxstaens, Raf Bisschops, Aaltje Lei, Marlies P. Schijven, Jan Guido Costamagna, Albert J. Bredenoord
Summary: This study compares the efficacy of POEM and PD for patients with persistent or recurrent symptoms after LHM. The results show that POEM has a higher success rate than PD, with a higher incidence of reflux esophagitis in the POEM group.
Article
Surgery
Alexander J. Podboy, Joo Ha Hwang, Homero Rivas, Dan Azagury, Mary Hawn, James Lau, Afrin Kamal, Shai Friedland, George Triadafilopoulos, Thomas Zikos, John O. Clarke
Summary: This study compared the long-term clinical efficacy of POEM versus HM for the treatment of achalasia. The results showed that both procedures have similar long-term efficacy, adverse event rates, and reflux rates, with POEM showing greater efficacy in Type III Achalasia.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Christopher Zimmermann, Nate Torell, Anne Lidor, Luke Funk, Amber Shada
Summary: Patients undergoing PD or POEM for recurrent dysphagia after myotomy have similar rates of dysphagia resolution and reflux symptoms.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Gastroenterology & Hepatology
Edoardo Vespa, Gaia Pellegatta, Viveksandeep T. Chandrasekar, Marco Spadaccini, Harsh Patel, Roberta Maselli, Piera A. Galtieri, Elisa Carlani, Prateek Sharma, Cesare Hassan, Alessandro Repici
Summary: Long-term clinical efficacy of POEM persisted in 87% of patients with achalasia. Post-POEM symptomatic reflux remained stable over time. The risk for Barrett's esophagus and peptic strictures appeared minimal.
Article
Surgery
Jocelyn de Heer, Madhav Desai, Guy Boeckxstaens, Giovanni Zaninotto, Karl-Hermann Fuchs, Prateek Sharma, Guido Schachschal, Oliver Mann, Thomas Roesch, Yuki Werner
Summary: The study found that the advent of peroral endoscopic myotomy (POEM) shed some light on the treatment of achalasia, however, existing meta-analyses comparing pneumatic dilatation (PD) and laparoscopic Heller myotomy (LHM) have unreliable conclusions. Future research should focus on conducting more randomized studies based on uniform criteria, while avoiding excessive meta-analyses.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Hong Jin, Bin Wang, Zhong-qing Zheng, Li-li Zhang, Qiu-yu Chen, Chun Shan Zhao, Bang-mao Wang, Wei Zhao
Summary: The study found that POEM therapy can effectively relieve symptoms in achalasia patients, even those who had previously undergone pneumatic dilation. There may be differences in fibrosis levels and complications between patients who underwent POEM after pneumatic dilation and those who did not. Longer follow-up studies with larger cohorts are needed to evaluate the long-term outcomes and complications of POEM.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Naoko Fukushima, Takahiro Masuda, Fumiaki Yano, Nobuo Omura, Kazuto Tsuboi, Masato Hoshino, Se Ryung Yamamoto, Shunsuke Akimoto, Yuki Sakashita, Norio Mitsumori, Hideyuki Kashiwagi, Toru Ikegami
Summary: This study evaluated the long-term outcomes of Laparoscopic Heller-myotomy with Dor fundoplication (LHD) for achalasia based on a single-center experience with a follow-up period exceeding 10 years. The study found that symptomatic relief post-LHD lasted for over 10 years, but there was a high incidence rate of esophageal cancer, highlighting the importance of regular EGD surveillance for early detection of esophageal cancer.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Joseph R. Triggs, Amanda J. Krause, Dustin A. Carlson, Erica N. Donnan, Ryan A. J. Campagna, Anand S. Jain, Peter J. Kahrilas, Eric S. Hungness, John E. Pandolfino
Summary: BOM is a common adverse event after myotomy for achalasia, associated with post-treatment symptom severity, achalasia type, and treatment modality. Pretreatment type III achalasia, LHM as opposed to POEM, and an increased post-treatment integrated relaxation pressure are risk factors for BOM development.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Megan Blaustein, Rachel Sillcox, Andrew S. Wright, Roger Tatum, Robert Yates, Mary Kate Bryant, Brant K. Oelschlager
Summary: This study aims to characterize gastroesophageal reflux disease (GERD) following laparoscopic Heller myotomy with Toupet fundoplication (LHM+T) in treated achalasia patients. The incidence of postoperative GERD burden is relatively low, but accurate diagnosis and differentiation from poor esophageal clearance in treated patients are important. Symptom correlation to abnormal pH study is unreliable, necessitating objective postoperative testing and manual review of abnormal pH studies.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Amy L. Holmstrom, Ryan J. Campagna, Dustin A. Carlson, John E. Pandolfino, Nathaniel J. Soper, Eric S. Hungness, Ezra N. Teitelbaum
Summary: The study demonstrates that both POEM and LHM significantly improved esophagogastric junction distensibility index (DI), with POEM resulting in a larger increase. There was a decrease in DI in the short-term postoperative period, followed by further improvement during follow-up, and the decrease in DI was predictive of the occurrence of esophagitis.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Shunsuke Akimoto, Fumiaki Yano, Nobuo Omura, Kazuto Tsuboi, Masato Hoshino, Se-Ryung Yamamoto, Takahiro Masuda, Yuki Sakashita, Naoko Fukushima, Hideyuki Kashiwagi, Toru Ikegami
Summary: For patients with failed Heller myotomy, rescue peroral endoscopic myotomy showed better surgical outcomes compared to redo laparoscopic Heller-Dor procedure, although it had higher rates of postoperative reflux esophagitis.
Article
Surgery
Valentina Tassi, Marialuisa Lugaresi, Vladimiro Pilotti, Francesco Bassi, Niccolo Daddi, Frank D'Ovidio, Miguel M. Leiva-Juarez, Sandro Mattioli
Summary: This study retrospectively analyzed the long-term outcomes of Heller myotomy for patients with esophageal achalasia. The results showed that Heller-Dor operation has a high cure rate and a low incidence of reflux.