Predicting Risk of Type 2 Diabetes Mellitus with Genetic Risk Models on the Basis of Established Genome-wide Association Markers: A Systematic Review

Joint Effects of Common Genetic Variants on the Risk for Type 2 Diabetes in U.S. Men and Women of European Ancestry

(2013) Marilyn C. Cornelis   ANNALS OF INTERNAL MEDICINE

Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement

(2013) A. Cecile J.W. Janssens   ANNALS OF INTERNAL MEDICINE

Inclusion of Gene-Gene and Gene-Environment Interactions Unlikely to Dramatically Improve Risk Prediction for Complex Diseases

(2012) Hugues Aschard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

(2012) Richa Saxena et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design

(2012) Alex H Cho et al.   BMC HEALTH SERVICES RESEARCH

European genetic variants associated with type 2 diabetes in North African Arabs

(2012) S. Cauchi et al.   DIABETES & METABOLISM

Personalized Genetic Risk Counseling to Motivate Diabetes Prevention: A randomized trial

(2012) R. W. Grant et al.   DIABETES CARE

A genotype risk score predicts type 2 diabetes from young adulthood: the CARDIA study

(2012) J. L. Vassy et al.   DIABETOLOGIA

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

(2012) Eli A Stahl et al.   NATURE GENETICS

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

(2012) Amélie Bonnefond et al.   NATURE GENETICS

Genotype Prediction of Adult Type 2 Diabetes From Adolescence in a Multiracial Population

(2012) J. L. Vassy et al.   PEDIATRICS

Comparing ROC curves derived from regression models

(2012) Venkatraman E. Seshan et al.   STATISTICS IN MEDICINE

Misuse of DeLong test to compare AUCs for nested models

(2012) Olga V. Demler et al.   STATISTICS IN MEDICINE

Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study

(2012) A. Abbasi et al.   BMJ-British Medical Journal

Evaluating the Incremental Value of New Biomarkers With Integrated Discrimination Improvement

(2011) K. F. Kerr et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

One statistical test is sufficient for assessing new predictive markers

(2011) Andrew J Vickers et al.   BMC Medical Research Methodology

Developing risk prediction models for type 2 diabetes: a systematic review of methodology and reporting

(2011) Gary S Collins et al.   BMC Medicine

Design of a randomized trial of diabetes genetic risk testing to motivate behavior change: The Genetic Counseling/Lifestyle Change (GC/LC) Study for Diabetes Prevention

(2011) Richard W Grant et al.   Clinical Trials

Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

(2011) M.-F. Hivert et al.   DIABETES

Globalization of Diabetes: The role of diet, lifestyle, and genes

(2011) F. B. Hu   DIABETES CARE

IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030

(2011) David R. Whiting et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Analysis of 32 common susceptibility genetic variants and their combined effect in predicting risk of Type 2 diabetes and related traits in Indians

(2011) C. S. Janipalli et al.   DIABETIC MEDICINE

Genetic predisposition to obesity leads to increased risk of type 2 diabetes

(2011) S. Li et al.   DIABETOLOGIA

Risk Assessment Tools for Identifying Individuals at Risk of Developing Type 2 Diabetes

(2011) B. Buijsse et al.   EPIDEMIOLOGIC REVIEWS

Use of reclassification for assessment of improved prediction: an empirical evaluation

(2011) Ioanna Tzoulaki et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Next-Generation DNA Sequencing, Regulation, and the Limits of Paternalism

(2011) James P. Evans et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

(2011) Yoon Shin Cho et al.   NATURE GENETICS

The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives

(2011) Lei Chen et al.   Nature Reviews Endocrinology

Effect of Direct-to-Consumer Genomewide Profiling to Assess Disease Risk

(2011) Cinnamon S. Bloss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve

(2010) Raluca Mihaescu et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism

(2010) Stephanie-May Ruchat et al.   ANNALS OF MEDICINE

Assessment of Improved Prediction Beyond Traditional Risk Factors

(2010) A. Cecile J.W. Janssens et al.   Circulation-Cardiovascular Genetics

Building Genetic Scores to Predict Risk of Complex Diseases in Humans: Is It Possible?

(2010) S. Liu et al.   DIABETES

Genetic Risk Reclassification for Type 2 Diabetes by Age Below or Above 50 Years Using 40 Type 2 Diabetes Risk Single Nucleotide Polymorphisms

(2010) J. M. de Miguel-Yanes et al.   DIABETES CARE

Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population

(2010) Q. Qi et al.   DIABETOLOGIA

Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population

(2010) B. Fontaine-Bisson et al.   DIABETOLOGIA

Inconsistent Results, Inaccurate Claims Plague Direct-to-Consumer Gene Tests

(2010) Bridget M. Kuehn   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identification of Undiagnosed Type 2 Diabetic Individuals by the Finnish Diabetes Risk Score and Biochemical and Genetic Markers: A Population-Based Study of 7232 Finnish Men

(2010) Jianjun Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Genomewide Association Studies and Assessment of the Risk of Disease

(2010) Teri A. Manolio   NEW ENGLAND JOURNAL OF MEDICINE

Combined Effects of 19 Common Variations on Type 2 Diabetes in Chinese: Results from Two Community-Based Studies

(2010) Min Xu et al.   PLoS One

Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers

(2010) Michael J. Pencina et al.   STATISTICS IN MEDICINE

Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men

(2009) Lu Qi et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Criteria for Evaluation of Novel Markers of Cardiovascular Risk

(2009) Mark A. Hlatky et al.   CIRCULATION

Use of Multiple Metabolic and Genetic Markers to Improve the Prediction of Type 2 Diabetes: the EPIC-Potsdam Study

(2009) M. B. Schulze et al.   DIABETES CARE

Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score—the CoLaus Study

(2009) X. Lin et al.   DIABETOLOGIA

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

(2009) T. Sparsø et al.   DIABETOLOGIA

Assessing the Performance of Prediction Models

(2009) Ewout W. Steyerberg et al.   EPIDEMIOLOGY

Evaluation of risk prediction updates from commercial genome-wide scans

(2009) Raluca Mihaescu et al.   GENETICS IN MEDICINE

Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association

(2009) Kazuaki Miyake et al.   JOURNAL OF HUMAN GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 Are Associated with Type 2 Diabetes in a Chinese Population

(2009) Cheng Hu et al.   PLoS One

Interpretation of Genetic Association Studies: Markers with Replicated Highly Significant Odds Ratios May Be Poor Classifiers

(2009) Johanna Jakobsdottir et al.   PLoS Genetics

A Critical Appraisal of the Scientific Basis of Commercial Genomic Profiles Used to Assess Health Risks and Personalize Health Interventions

(2008) A. Cecile J.W. Janssens et al.   AMERICAN JOURNAL OF HUMAN GENETICS

TCF7L2variant genotypes and type 2 diabetes risk in Brazil: significant association, but not a significant tool for risk stratification in the general population

(2008) GF Marquezine et al.   BMC Medical Genetics

Getting Up Close and Personal with Your Genome

(2008) Laura Bonetta   CELL

Predicting Type 2 Diabetes Based on Polymorphisms From Genome-Wide Association Studies: A Population-Based Study

(2008) M. van Hoek et al.   DIABETES

Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk

(2008) H. Lango et al.   DIABETES

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes

(2008) James B. Meigs et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Post Genome-Wide Association Studies of Novel Genes Associated with Type 2 Diabetes Show Gene-Gene Interaction and High Predictive Value

(2008) Stéphane Cauchi et al.   PLoS One