Article
Endocrinology & Metabolism
Bunpei Ishizuka, Masataka Furuya, Machiko Kimura, Eri Kamioka, Kazuhiro Kawamura
Summary: The study analyzed the effectiveness of HR treatment on patients with POI, showing that OS combined with HR therapy can increase fertility rates, especially in the IVF-1-a and IVF-2 groups.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Judith Ong, Suresh Anand Sadananthan, Shu-E Soh, Sharon Ng, Wen Lun Yuan, Izzuddin M. Aris, Mya Thway Tint, Navin Michael, See Ling Loy, Kok Hian Tan, Keith M. Godfrey, Lynette P. Shek, Fabian Yap, Yung Seng Lee, Yap Seng Chong, Shiao-Yng Chan
Summary: The study found that severe nausea and vomiting of pregnancy (NVP) was associated with late preterm delivery, and both mild-moderate and severe NVP were linked to sex-dependent differences in early childhood growth. Boys born to mothers with NVP were taller and heavier from birth with faster growth in the first year, while girls had poorer weight gain and were lighter by 48 months.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Review
Endocrinology & Metabolism
Manuel S. Vidal, Ryan C. V. Lintao, Mary Elise L. Severino, Ourlad Alzeus G. Tantengco, Ramkumar Menon
Summary: Survivors of preterm birth face various disabilities, and addressing the rates of low birth weight, neonatal and maternal morbidities and mortalities is crucial. Research has provided theories on risk factors and clinical manifestations, but there is a lack of biomarkers for early diagnosis. To overcome current limitations, an integrated approach studying the network interaction between different tissues and organs is needed.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Physiology
Huiyun Chen, Yu Gong, Fangcan Sun, Bing Han, Bingyuan Zhou, Jiali Fan, Xinxian Gu
Summary: This study used two-dimensional speckle tracking echocardiography to evaluate myocardial strain in preterm children aged 5 to 8 years with severe preeclampsia. The results showed that severe preeclampsia did not have a significant impact on cardiac structure in premature children at this age, but they had a higher resting heart rate which may be associated with long-term cardiovascular disease.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Endocrinology & Metabolism
Xue Jiao, Tingting Meng, Yiwei Zhai, Lijuan Zhao, Wei Luo, Peihao Liu, Yingying Qin
Summary: Ovarian reserve indicators deteriorate with the progression of ovarian insufficiency, with an increase in FSH and LH but a decrease in AMH, inhibin B, AFC, E-2 and T. AMH has the highest predictive value for POI, and the combination of AMH and AFC is promising for early prediction. Significant differences exist in hormone status among women with different etiologies of POI, with genetic POI showing the worst hormone status.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Cell Biology
Seung Joo Chon, Zobia Umair, Mee-Sup Yoon
Summary: Premature ovarian insufficiency (POI) is a condition characterized by the loss of normal ovarian function before the age of 40, affecting a small percentage of women under 40. The condition is biochemically defined by amenorrhea, low estrogen levels, and high gonadotropin levels, potentially leading to infertility. POI has a heterogeneous etiology, including both genetic and non-genetic factors, and current research focuses on genetic basis, non-coding RNA, and animal models to uncover pathogenesis and potential treatment targets. Despite recent advances, understanding gene regulatory networks and exploring therapies remain critical for future research.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Qingling Yang, Sezcan Mumusoglu, Yingying Qin, Yingpu Sun, Aaron J. Hsueh
Summary: Ovarian infertility and subfertility are major challenges in developed countries due to the trend of delayed childbirth. Through genetic studies, genes related to premature ovarian insufficiency and ovarian senescence have been identified, especially those crucial for DNA repair, meiosis, and mitochondrial functions.
Article
Obstetrics & Gynecology
X. Ruan, J. Du, D. Lu, W. Duan, F. Jin, W. Kong, Y. Wu, Y. Dai, S. Yan, C. Yin, Y. Li, J. Cheng, C. Jia, X. Liu, Q. Wu, M. Gu, R. Ju, X. Xu, Y. Yang, J. Jin, M. Korell, M. Montag, J. Liebenthron, A. O. Mueck
Summary: This article reports the first live birth resulting from ovarian tissue cryopreservation and transplantation in China. It provides a new treatment option for premature ovarian insufficiency.
Article
Oncology
Lucas W. Thornblade, Ernest Han, Yuman Fong
Summary: Patients with colorectal cancer ovarian metastasis have favorable long-term survival. Survival rates are higher if the tumor is isolated to the ovary or if metachronous to the primary cancer.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Reproductive Biology
Xiaodan Lv, Chunyi Guan, Ying Li, Xing Su, Lu Zhang, Xueqin Wang, Hong-Fei Xia, Xu Ma
Summary: This study investigated the efficacy of human umbilical cord blood mesenchymal stem cells (hUC-MSCs) in treating chemotherapy-induced premature ovarian failure (POF). The results demonstrated that multiple injections of hUC-MSCs were more effective in restoring ovarian function compared to single injections.
JOURNAL OF OVARIAN RESEARCH
(2021)
Article
Endocrinology & Metabolism
Jingyi Wen, Yanzhi Feng, Wei Yan, Suzhen Yuan, Jinjin Zhang, Aiyue Luo, Shixuan Wang
Summary: This study reveals the characteristics of vaginal microbiota in POI patients and their relationship with reduced ovarian reserve, endocrine disruption, and symptoms of perimenopausal syndrome. Differences in vaginal microbiota between POI and POF patients are also identified.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Tahereh Changiz, Mahboobeh Namnabati
Summary: This study focused on the comprehensive care management experience of two sets of multiple premature infants over a two-year period, addressing challenges and strategies in areas such as infertility, NICU transition, discharge process, physical and developmental status, home care, care plan development, socio-economic support, and the impact of the coronavirus pandemic. Collaboration between Isfahan University of Medical Sciences, Welfare Organization, and charities was found to be crucial in providing inter-professional care for these infants and their families, emphasizing the need for a specific package of comprehensive care management plan for multiple-births.
Article
Obstetrics & Gynecology
Zahra Najafi, Mojgan Mirghafourvand, Solmaz Ghanbari-Homaie
Summary: The occurrence of preterm birth can lead to negative perception towards birth, but there is no significant difference in childbirth experience between mothers with term and preterm births. However, fear of delivery during labour has a significant relationship with childbirth experience. Interventions to reduce fear during labour should be implemented to improve women's childbirth experience.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Psychology, Multidisciplinary
Gozde Gokce Isbir, Figen Inci, Burcu Komurcu Akik, Wilson Abreu, Gill Thomson
Summary: This study aimed to investigate factors associated with birth-related post-traumatic stress disorder (PTSD) among women who had preterm birth in Turkey. The results showed that older age, positive impact from mother's birth experience, absence of traumatic experiences during pregnancy and postnatal period, lower stress level after traumatic events during birth, not feeling at risk during birth, amniotomy, psychological well-being after childbirth, not being negatively affected by witnessing other parents' happy moments with their babies, absence of infant illness, and positive interactions with healthcare team were associated with decreased likelihood of birth-related PTSD.
CURRENT PSYCHOLOGY
(2023)
Article
Cell Biology
Linlin Liu, Huasong Wang, Guo Liang Xu, Lin Liu
Summary: Tet enzymes, specifically Tet1, are crucial for DNA demethylation and have a significant impact on stem cell differentiation and pluripotency. The deficiency of Tet1 can lead to accelerated reproductive failure due to decreased follicle reserve and other molecular changes in oocytes, indicating a potential link to premature ovarian failure.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Environmental Sciences
Kyoko Miura, Minas Coroneo, Jean Claude Dusingize, Catherine M. Olsen, Rick Tinker, Ken Karipidis, Ian Hosegood, Adele C. Green
Summary: This study estimated the prevalence of cataract in pilots by analyzing medical records of commercial airline pilots diagnosed with cataract between 2011 and 2016. The results showed that the prevalence of cataract in pilots aged 60 and above was 11.6%, while it was only 0.5% in pilots aged below 60. The study also found that there was no significant difference in cataract prevalence based on the ambient ultraviolet radiation levels, although the lowest prevalence was observed in the low-UV state of Victoria. Furthermore, cataracts in pilots aged 60 and above were mostly bilateral and mild, while cataracts in pilots below 60 were more likely to be unilateral and severe.
ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
(2023)
Article
Gastroenterology & Hepatology
Julia Schroeder, Laura Chegwidden, Carlo Maj, Jan Gehlen, Jan Speller, Anne C. Boehmer, Oleg Borisov, Timo Hess, Nicole Kreuser, Marino Venerito, Hakan Alakus, Andrea May, Christian Gerges, Thomas Schmidt, Rene Thieme, Dominik Heider, Axel M. Hillmer, Julian Reingruber, Orestis Lyros, Arne Dietrich, Albrecht Hoffmeister, Matthias Mehdorn, Florian Lordick, Gertraud Stocker, Michael Hohaus, Daniel Reim, Jennis Kandler, Michaela Mueller, Alanna Ebigbo, Claudia Fuchs, Christiane J. Bruns, Arnulf H. Holscher, Hauke Lang, Peter P. Grimminger, Dani Dakkak, Yogesh Vashist, Sandra May, Siegfried Gorg, Andre Franke, David Ellinghaus, Sara Galavotti, Lothar Veits, Josef Weismuller, Jens Dommermuth, Udo Benner, Thomas Roesch, Helmut Messmann, Brigitte Schumacher, Horst Neuhaus, Carsten Schmidt, Thaddaus T. Wissinowski, Markus M. Noethen, Jing Dong, Jue-Sheng Ong, Matthew F. Buas, Aaron P. Thrift, Thomas L. Vaughan, Ian Tomlinson, David C. Whiteman, Rebecca Claire Fitzgerald, Janusz Jankowski, Michael Vieth, Andreas Mayr, Puya Gharahkhani, Stuart MacGregor, Ines Gockel, Claire Palles, Johannes Schumacher
Summary: This study utilized GWAS, genetic correlation analysis, and polygenic risk modeling to investigate the genetic causes of BE/EA. The findings identified new risk loci and candidate genes associated with BE/EA development. The study also revealed differences in the etiology of BE and EA and demonstrated improved risk prediction models when combining PRS with risk factors. These findings provide valuable insights into the mechanisms underlying BE/EA and improve our understanding of the disease.
Article
Oncology
Azam Majidi, Renhua Na, Susan J. Jordan, Anna DeFazio, Andreas Obermair, Michael Friedlander, Peter Grant, Penelope M. Webb
Summary: This study investigated the association between nonsteroidal antiinflammatory drug (NSAID) use and 5-year cancer-specific survival in Australian women with ovarian cancer. The results showed that frequent use of NSAIDs, including aspirin and nonaspirin NSAIDs, was associated with better survival compared to nonusers and infrequent users. These findings suggest that NSAID use might improve ovarian cancer survival.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Dermatology
Catherine M. Olsen, Nirmala Pandeya, Jean Claude Dusingize, Rachel E. Neale, Stuart MacGregor, Matthew H. Law, David C. Whiteman
Summary: This cohort study compares the clinical characteristics of first and second melanomas and finds that individuals with second primary melanomas are more likely to have more nevi and higher genetic predisposition for melanoma compared to those with only one melanoma.
Article
Dermatology
Ashley Ahimbisibwe, Morten Valberg, Adele C. Green, Reza Ghiasvand, Corina S. Rueegg, Raju Rimal, Elisabete Weiderpass, Torkjel M. Sandanger, Trude E. Robsahm, Marit B. Veierod
Summary: This study investigated the association between nevus count and pigmentary characteristics with melanoma-specific mortality. The study found that in patients with thicker melanoma, darker pigmentary characteristics were associated with a higher risk of melanoma death. However, in women with thicker melanoma, lighter pigmentary characteristics and asymmetrical nevi may be associated with lower melanoma-specific mortality.
ACTA DERMATO-VENEREOLOGICA
(2023)
Editorial Material
Dermatology
Catherine M. Olsen, Louisa G. Gordon, Stacy M. Carter, David C. Whiteman
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Letter
Dermatology
Reza Ghiasvand, Leon A. M. Berge, Bettina K. Andreassen, Adele C. Green, Marie Al Rahmoun, Agnes Fournier, Marina Kvaskoff, Marit B. Veierod, Trude E. Robsahm
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Oncology
Marjorie M. A. de Souza, Gunter Hartel, Catherine M. Olsen, David C. Whiteman, Annika Antonsson
Summary: This Australian-based study assessed the prevalence of oral HPV infection in Australian residents and found that the prevalence was 7.2%. The study also found a strong association between oral HPV infection and sexual behaviors, and suggested that HPV vaccination may result in a lower risk of infection with nonavalent HPV types.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Medicine, General & Internal
Nirmala Pandeya, Catherine M. Olsen, Maja M. Shalit, Jean Claude Dusingize, Rachel E. Neale, David C. Whiteman
Summary: This study aimed to determine the proportions of newly diagnosed melanomas treated by different medical specialist types, describe the types of excisions performed, and investigate factors associated with treating practitioner specialty and excision type. The results showed that most melanomas were diagnosed in primary care, and nearly half of the cases were initially managed by partial excision (shave or punch biopsy). Second or third, wider excisions were undertaken in about 90% of cases.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Multidisciplinary Sciences
David M. Goldsbury, Amy Vassallo, Marianne Weber, Julia Steinberg, Penelope Webb, Anna DeFazio, Karen Canfell
Summary: This study aimed to estimate the direct health system costs of women diagnosed with ovarian cancer in Australia during 2006-2013, and found that the costs are substantial. Continued investment in ovarian cancer research, including prevention, early detection, and personalized treatments, is necessary to reduce the burden of the disease.
Article
Dermatology
Nirmala Pandeya, Jean Claude Dusingize, Catherine M. Olsen, Stuart Macgregor, Rachel E. Neale, Matthew H. Law, David C. Whiteman
Summary: Genetic risk is weakly associated with melanoma incidence and screening behavior, but it does not explain the higher rate of melanoma detection between screened and unscreened individuals.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Dermatology
Catherine M. Olsen, Nirmala Pandeya, Bruna S. Ragaini, Rachel E. Neale, David C. Whiteman
Summary: We compared the incidence trends of cutaneous SCC (cSCC) and melanoma in populations residing at mid-to-high latitudes and found that the ratio of cSCC-to-melanoma incidence increased with proximity to the equator and over time, especially in women.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Medicine, General & Internal
Daniel Lindsay, David C. Whiteman, Catherine M. Olsen, Louisa G. Gordon
Summary: This study quantifies the differences in health care service use by people diagnosed with invasive melanoma in Queensland, Australia, based on their residential remoteness and socio-economic status. The analysis shows that there are minor variations in hospital admissions and specialist consultations, with public hospital admissions more frequent in areas of greater socio-economic disadvantage and outside major cities, while private hospital admissions and specialist consultations are more frequent in areas of lesser disadvantage and in major cities.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Dermatology
Nirmala Pandeya, Nancy Huang, Zainab Jiyad, Elsemieke Plasmeijer, Mandy Way, Nicole Isbel, Scott Campbell, Daniel C. Chambers, Peter Hopkins, H. Peter Soyer, David C. Whiteman, Catherine M. Olsen, Adele C. Green
Summary: Organ transplant recipients (OTRs) have a higher risk of basal cell carcinomas (BCCs) compared to the general population. There are some differences in the clinicopathologic features of BCCs between OTRs and the general population. Although aggressive subtypes of BCCs are less common in OTRs, BCCs that invade beyond the dermis are almost twice as prevalent in OTRs compared to the general population.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
M. Shakeel, Z. Jiyad, M. Grant, M. G. Cook, D. Oudit, A. C. Green
Summary: The occurrence of lower limb melanoma in women is higher, but it varies across subsites and age groups. This might be linked to the relative influence of genetic and environmental risk factors.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
