Article
Geriatrics & Gerontology
Elzbieta Gradek-Kwinta, Agnieszka Slowik, Tomasz Dziedzic
Summary: The study found that the use of anticholinergic medication before stroke is associated with an increased risk of stroke-associated pneumonia (SAP), suggesting that the use of anticholinergic medication may increase the risk of pneumonia after a stroke.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Clinical Neurology
Jenny Stritzelberger, Johannes D. Lang, Tamara M. Mueller, Caroline Reindl, Vivien Westermayer, Karel Kostev, Hajo M. Hamer
Summary: The debate over whether anti-seizure medication increases the risk for cancer has been ongoing for decades. However, a study using anonymous patient data collected by neurologists in Germany from 2009 to 2018 suggests that there is no increase in cancer risk for epilepsy patients using anti-seizure medication.
JOURNAL OF NEUROLOGY
(2021)
Article
Computer Science, Information Systems
Joanna Abraham, William L. Galanter, Daniel Touchette, Yinglin Xia, Katherine J. Holzer, Vania Leung, Thomas Kannampallil
Summary: By utilizing a computerized order entry system-integrated function named void, the study aimed to identify the nature and characteristics of medication ordering errors, investigate associated risk factors, and explore strategies to mitigate these risks. Results showed that medication ordering errors were multifactorial and mostly did not result in harm to patients.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Article
Behavioral Sciences
Randeniya Roshini, Mattingley B. Jason, Garrido Marta
Summary: The study found no significant differences in auditory context adjustment between autistic and neurotypical individuals, but a positive correlation between context-dependent prediction errors and subjective reports of auditory sensitivities. This suggests that perceptual alterations may be more influenced by sensory sensitivities than autistic traits. Further research in EEG studies on autism may benefit from considering sensory sensitivities.
Article
Rheumatology
Ruth E. Costello, Belay B. Yimer, Polly Roads, Meghna Jani, William G. Dixon
Summary: The study found an association between the use of glucocorticoids and incident hypertension in patients with rheumatoid arthritis, especially at doses >= 7.5 mg. Clinicians should consider cardiovascular risk when prescribing glucocorticoids, and ensure regular monitoring and treatment of blood pressure.
Article
Cell Biology
Xian Dong, Yang He, Jingang An, Linhai He, Yi Zheng, Xinyu Wang, Jie Wang, Shuo Chen, Yi Zhang
Summary: This study investigated the relationship between autophagy and apoptosis in MRONJ gingival epithelium and searched for a preventive method for this disease.
Article
Public, Environmental & Occupational Health
Kumiko O. Schnock, Sara E. Rostas, Catherine S. Yoon, Stuart Lipsitz, David W. Bates, Patricia C. Dykes
Summary: This study investigated intravenous medication administration errors in the NICU using smart infusion pumps. A total of 441 patients with 905 IV medication administrations were observed, and 130 errors were identified. The most frequent errors were selecting the wrong drug library entry, unauthorized medication, and wrong dose. 68 errors were unlikely to cause harm to patients, while the rest did not reach the patient.
Article
Endocrinology & Metabolism
Dana Bliuc, Thach Tran, Weiwen Chen, Dunia Alarkawi, Dima A. Alajlouni, Fiona Blyth, Lyn March, Robert D. Blank, Jacqueline R. Center
Summary: This study aimed to determine the association between oral bisphosphonate (oBP) or denosumab (Dmab) use and cardiovascular events (CVEs). The results showed that there was no association between oBP or Dmab use and CVEs.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Medicine, General & Internal
Sven H. Loosen, Karel Kostev, Tom Luedde, Christoph Roderburg
Summary: Infectious mononucleosis is significantly associated with the incidence of non-alcoholic fatty liver disease (NAFLD), and this association is most pronounced in older age groups.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Geriatrics & Gerontology
Jessica A. Lockery, Taya L. Collyer, Robyn G. Woods, Suzanne Orchard, Anne R. Murray, Mark P. Nelson, Nigel Stocks, Rory Wolfe, Chris E. Moran, Michael Ernst
Summary: This study investigated the impact of potentially inappropriate medication (PIMs) use on community-dwelling older adults. The results showed that PIMs use was associated with increased risk of disability and hospitalization, emphasizing the importance of caution when prescribing PIMs to healthy older adults.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Oncology
Christoph Roderburg, Sven H. Loosen, Markus S. Joerdens, Munevver Demir, Tom Luedde, Karel Kostev
Summary: There is evidence suggesting that the consumption of antibiotics may change the microbiome and create an environment that promotes cancer development. However, the association between antibiotic intake and cancer incidence has remained inconclusive. In this retrospective case-control study, the intake of different antibiotics was quantified and their association with various cancer entities was examined among outpatients from Germany.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Respiratory System
Robert J. Maidstone, James Turner, Celine Vetter, Hassan S. Dashti, Richa Saxena, Frank A. J. L. Scheer, Steven A. Shea, Simon D. Kyle, Deborah A. Lawlor, Andrew S. Loudon, John F. Blaikley, Martin K. Rutter, David W. Ray, Hannah Jane Durrington
Summary: Shift work, especially night shifts, is associated with a higher likelihood of moderate-severe asthma. Individuals who engage in any type of shift work also have a higher risk of wheeze/whistling in the chest. Additionally, morning chronotypes working irregular shifts, including nights, are at an increased risk of moderate-severe asthma.
Article
Immunology
Qiuting Yan, Shengshi Huang, Wouter van der Heijden, Marisa Ninivaggi, Lisa van de Wijer, Romy de Laat-Kremers, Andre J. van der Ven, Bas de Laat, Quirijn de Mast
Summary: This study further explores the relationship between abacavir (ABC) use and thrombin generation through thrombin dynamics analysis, and finds that the association between ABC use and thrombin generation may be due to an increase in the prothrombin conversion pathway. In a cross-sectional study of 208 virally suppressed PLHIV, it is found that the total amount and maximum rate of prothrombin conversion are significantly increased in PLHIV on an ABC-containing regimen, indicating that ABC affects the kinetics of prothrombin conversion rather than procoagulant factor levels.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Health Care Sciences & Services
Corey A. Lester, Jiazhao Li, Yuting Ding, Brigid Rowell, Jessie 'Xi' Yang, Raed Al Kontar
Summary: Utilizing machine intelligence to assist pharmacist verification tasks has the potential to detect dangerous pharmacy dispensing errors. Automated checks were used to predict shape, color, and NDC for images of pills in prescription bottles, with a macro-average precision of 98.5%. Patterns of incorrect NDC predictions based on similar colors, shapes, and imprints of pills were identified and recommendations for improving the model were provided.
NPJ DIGITAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Jiarong Xie, Hangkai Huang, Yishu Chen, Lei Xu, Chengfu Xu
Summary: In individuals with metabolic dysfunction-associated fatty liver disease (MAFLD), skipping breakfast is associated with a higher risk of cardiovascular mortality, while there is no such association in MAFLD-free individuals.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Review
Cardiac & Cardiovascular Systems
Lisa W. M. Leung, Mark M. Gallagher, Pasquale Santangeli, Cory Tschabrunn, Jose M. Guerra, Bieito Campos, Jamal Hayat, Folefac Atem, Steven Mickelsen, Erik Kulstad
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2020)
Article
Critical Care Medicine
Nathaniel Bonfanti, Emily Gundert, Anisha Malhotra, Jessica Saleh, Erik Kulstad
Letter
Cardiac & Cardiovascular Systems
Shailee Shah, Marcela Mercado-Montoya, Jason Zagrodzky, Erik Kulstad
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Article
Engineering, Biomedical
Marcela Mercado, Lisa Leung, Mark Gallagher, Shailee Shah, Erik Kulstad
BIOMEDICAL ENGINEERING ONLINE
(2020)
Article
Multidisciplinary Sciences
Nathaniel Bonfanti, Emily Gundert, Anne M. Drewry, Kristina Goff, Roger Bedimo, Erik Kulstad
Letter
Cardiac & Cardiovascular Systems
Brad Clark, Erik Kulstad
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Letter
Cardiac & Cardiovascular Systems
James Daniels, Erik Kulstad
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Virology
Dominique Kang, Clifford Ellgen, Erik Kulstad
Summary: Data suggests that SARS-CoV-2 replication is increased in the upper airways at lower temperatures, contributing to more rapid viral growth and transmission. Therefore, raising the temperature in the upper airways could potentially slow down disease progression and transmission.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Oncology
Marcela Mercado-Montoya, Tatiana Gomez-Bustamante, Enrique Berjano, Steven Mickelsen, James Daniels, Pablo Hernandez-Arango, Jay Schieber, Erik Kulstad
Summary: Proactive esophageal cooling significantly reduces temperatures and damage in the esophagus during high-power short-duration ablation. These findings provide a mechanistic rationale for the high level of safety achieved so far using proactive esophageal cooling and highlight the inadequacy of temperature monitoring alone in avoiding thermal damage to the esophagus.
INTERNATIONAL JOURNAL OF HYPERTHERMIA
(2022)
Article
Multidisciplinary Sciences
Christopher Joseph, Julie Cooper, Robert W. Turer, Samuel A. McDonald, Erik Benjamin Kulstad, James Daniels
Summary: This study aimed to measure the effects of two different esophageal protection strategies on procedure time and variability in procedure time during radiofrequency pulmonary vein isolation (PVI). The results showed that active esophageal cooling during PVI is associated with reduced procedure time and reduced variation in procedure time.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2022)
Review
Engineering, Biomedical
Julie Cooper, Christopher Joseph, Jason Zagrodzky, Christopher Woods, Mark Metzl, Robert W. W. Turer, Samuel A. A. McDonald, Erik Kulstad, James Daniels
EXPERT REVIEW OF MEDICAL DEVICES
(2022)
Article
Cardiac & Cardiovascular Systems
Christopher Joseph, Jose Nazari, Jason Zagrodzky, Babette Brumback, Jacob Sherman, William Zagrodzky, Shane Bailey, Erik Kulstad, Mark Metzl
Summary: This study compared the difference in arrhythmia recurrence rates at 1 year between patients treated with luminal esophageal temperature monitoring and those treated with active esophageal cooling during left atrial ablation. The results showed that patients treated with active esophageal cooling had a lower incidence of arrhythmia recurrence at 1 year, and this difference was statistically significant. However, more rigorous prospective or randomized studies are needed to validate these findings.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Marcela Mercado-Montoya, Tatiana Gomez-Bustamante, Erik B. Kulstad, Enrique Berjano, Steven R. Mickelsen, Pablo Hernandez-Arango, Jay Schieber, James D. Daniels
CIRCULATION RESEARCH
(2022)
Letter
Critical Care Medicine
Anne M. Drewry, Richard Hotchkiss, Erik Kulstad
Letter
Critical Care Medicine
Anne M. Drewry, Richard Hotchkiss, Erik Kulstad
Letter
Emergency Medicine
Zhao-Yu Hsieh, Chen-Xiong Hsu
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Laura E. Walker, Jessica A. Stanich, Fernanda Bellolio
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
E. Tekin
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amanda S. Dupont, Patrick S. Walsh
Summary: Recent research indicates that children who unintentionally ingest cannabis often undergo extensive additional testing, such as head imaging or lumbar puncture. However, the yield of these tests is limited. While head imaging and lumbar puncture are frequently performed, diagnoses such as skull fracture, intracranial hemorrhage, intracranial neoplasm, meningitis, or intracranial abscess are rare. Additionally, discharge diagnoses related to other drugs are infrequent. The most common co-diagnoses are cocaine and opioids. Therefore, prompt consideration of cannabis ingestion and quick identification through testing may result in more effective neuroimaging outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
Mio Nagata, Shunsuke Kudo, Motoyasu Nakamura
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Andy Hung-Yi Lee, Katherine Dickerson Mayes, Regan Marsh, Christina Toledo-Cornell, Eric Goralnick, Michael Wilson, Leon D. Sanchez, Alice Bukhman, Damarcus Baymon, Dana Im, Paul C. Chen
Summary: This study assessed the disparities in transferring patients from an academic medical center emergency department to a community hospital general medical service, revealing healthcare disparities among different patient populations.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Annabelle Croskey, William Trautman, David Barton, Mary Kathleen Ratay, Joshua Shulman
Summary: This case report describes a successful management of ocular palytoxin exposure in a young male, highlighting the importance of prompt recognition and treatment of ocular PTX toxicity.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Matthew K. Kolbeck, Rachel F. Schult, Nicholas Nacca
Summary: This article presents four cases of adolescents who experienced seizures after acute fluoxetine overdose. Although seizures are an uncommon complication after fluoxetine overdose, they occurred in some patients at doses lower than those reported in the literature.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Daven Patel, John Bailitz, Simone Ymson, Jonas Neichin, Gary D. Peksa, Michael Gottlieb
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amichai Gutgold, Shaden Salameh, Jeries Nashashibi, Yonatan Gershinsky
Summary: This study aimed to test the prognosis of patients with a pH lower than 6.9 on emergency department admission. The findings showed that a small but significant portion of these patients survived at least 24 hours and until hospital discharge.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Na-Yeon Emily Song, Ki Hong Kim, Ki Jeong Hong
Summary: This study aimed to evaluate the effect of the duration of no-flow (NF) interval on the vaso-pressor effect of initial epinephrine administration in a porcine model of cardiac arrest. The results showed that a shorter NF interval can enhance the vasopressor effect of epinephrine.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Kenneth A. Scheppke, Paul E. Pepe, Jonathan Jui, Remle P. Crowe, Eric K. Scheppke, Nancy G. Klimas, Aileen M. Marty
Summary: This study reported cases of rapid and complete remission of severe long COVID after receiving monoclonal antibody treatment. The findings suggest that monoclonal antibody infusions may be effective in treating severe debilitation caused by long COVID.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Suhrith Bhattaram, Varsha S. Shinde
Summary: Nerve blocks have emerged as promising options for targeted pain relief in the Emergency Department, providing effective analgesia without compromising motor function. The successful use of ultrasound-guided genicular nerve blocks (GNBs) in this case series demonstrates their potential as an alternative to traditional nerve blocks and opioid-based pain control strategies in the ED.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Rick Kye Gan, Jude Chukwuebuka Ogbodo, Yong Zheng Wee, Ann Zee Gan, Pedro Arcos Gonzalez
Summary: The aim of this study was to evaluate and compare the performance of ChatGPT, Google Bard, and medical students in performing START triage during mass casualty situations. The results showed that Google Bard had significantly higher accuracy compared to ChatGPT, while there was no significant difference between Google Bard and medical students.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Nancy Clemens, Paria M. Wilson, Matthew J. Lipshaw, Holly Depinet, Yin Zhang, Michelle Eckerle
Summary: This study compared clinical features and outcomes between pediatric sepsis patients with blood cultures positive versus negative for bacterial pathogens. The results showed that children with blood culture positive sepsis had higher rates of organ dysfunction, a larger base deficit, and higher procalcitonin levels.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)