Article
Medicine, General & Internal
Se Hyun Oh, Ju Hyeon Kim, Seung Tae Seong, Jun Young Park, Jae Hyun Lee, Ghi Chan Kim, Ho Joong Jeong, Young Joo Sim
Summary: This study investigated the impact of axillary site radiation therapy on lymphoscintigraphy in breast cancer-related lymphedema patients who underwent sentinel lymph node dissection. The results suggest that both SLND and aRTx affect the activity of axillary lymph nodes and adversely affect lymphatic flow, becoming risk factors for lymphedema. Additionally, lymphedema may develop even in patients with normal lymphoscintigraphy.
Article
Oncology
Lotte Poulsen, Manraj Kaur, Amalie L. Jacobsen, Mie P. Bjarnesen, Anna P. Bjarnesen, Anne F. Klassen, Andrea L. Pusic, Claire E. E. de Vries, Jens A. Sorensen
Summary: This study aimed to assess the impact of SLND and ALND on the HRQOL in women diagnosed with BCRL, and found no significant difference in the LYMPH-Q UE module scales between the two groups.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Review
Surgery
Nur Amalina Che Bakri, Richard M. Kwasnicki, Naairah Khan, Omar Ghandour, Alice Lee, Yasmin Grant, Aleksander Dawidziuk, Ara Darzi, Hutan Ashrafian, Daniel R. Leff
Summary: This study evaluated the impact of axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB) on upper limb morbidity in breast cancer patients. The results showed that ALND patients had higher prevalence of lymphedema, pain, reduced strength, and range of motion compared with SLNB patients. These findings support the continued de-escalation of axillary surgery.
Article
Oncology
Qianqian Yuan, Jinxuan Hou, Yukun He, Yiqian Liao, Lewei Zheng, Gaosong Wu
Summary: ALND based on BLL can minimize surgical extent for node-positive breast cancer patients, potentially reducing the occurrence of BCRL.
Article
Oncology
Hope M. Guzzo, Stephanie A. Valente, Graham S. Schwarz, Ayat ElSherif, Stephen R. Grobmyer, Cagri Cakmakoglu, Risal Djohan, Steven Bernard, Julie E. Lang, Debra Pratt, Zahraa Al-Hilli
Summary: The study evaluated the safety and recurrence rates of immediate lymphatic reconstruction (ILR) in breast cancer patients undergoing axillary lymph node dissection (ALND). The results showed that ILR during ALND was not associated with short-term axillary recurrence and appeared to be oncologically safe.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Health Care Sciences & Services
Raimund Winter, Alexandru Tuca, Paul Wurzer, Caroline Schaunig, Isabelle Sawetz, Judith C. J. Holzer-Geissler, Daniel Georg Gmainer, Hanna Luze, Herwig Friedl, Erika Richtig, Lars-Peter Kamolz, David Benjamin Lumenta
Summary: For patients undergoing completion axillary lymph node dissection for melanoma, removing drains around the 8th postoperative day can reduce the risk of seroma formation and related complications. Most complications can be managed conservatively, with only a small percentage requiring revision surgery.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Oncology
Ji Young You, Eun Sook Lee, Siew Kuan Lim, Youngmee Kwon, So-Youn Jung
Summary: According to the study, performing sentinel lymph node biopsy (SLNB) without axillary lymph node dissection (ALND) may be a reasonable treatment option for patients with positive lymph nodes after breast cancer surgery. There was no significant difference in the loco-regional recurrence rates between SLNB with ALND and SLNB alone.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Peiyong Li, Ciqiu Yang, Junsheng Zhang, Yitian Chen, Xiaoqi Zhang, Minting Liang, Na Huang, Yilin Chen, Kun Wang
Summary: Sentinel lymph node biopsy can provide survival results equivalent to axillary lymph node dissection for patients with cN0 and T1-2 breast cancer; however, whether it can be performed on patients with T3-4c breast cancer is still controversial.
Article
Oncology
Ian Campbell, Neil Wetzig, Owen Ung, David Espinoza, Gelareh Farshid, John Collins, James Kollias, Val Gebski, Rebecca Mister, R. John Simes, Martin R. Stockler, Grantley Gill
Summary: For early breast cancer patients who are clinically node-negative, sentinel node-based management (SNBM) is the international standard of care. In the SNAC1 study, we report the rates of axillary recurrence, overall survival, and breast cancer-specific survival at 10 years.
Article
Oncology
Nur Amalina Che Bakri, Richard M. Kwasnicki, Emmanuel Giannas, Luqman Tenang, Naairah Khan, Catharina Moenig, Zoha Imam, Kieran Dhillon, Hutan Ashrafian, Ara Darzi, Daniel R. Leff
Summary: Objective assessment using wearable activity monitors (WAMs) shows that axillary lymph node dissection (ALND) results in lower physical activity (PA) levels compared with sentinel lymph node biopsy (SLNB), and SLNB has a protracted effect on PA levels up to 2 weeks postoperatively.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, General & Internal
Kelsey Lipman, Anna Luan, Kimberly Stone, Irene Wapnir, Mardi Karin, Dung Nguyen
Summary: This study highlights the LYMPHA technique as a feasible and effective method for prevention of lymphedema. By performing lymphatic mapping and lymphaticovenous anastomosis during the primary surgery, the morbidity associated with lymphedema can be avoided. A retrospective review showed successful prevention of lymphedema with minimal surgical complications.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Sophie H. H. Chung, Susanna W. L. de Geus, Grant Shewmaker, Kelsey S. S. Romatoski, Frederick T. T. Drake, Naomi Y. Y. Ko, Andrea L. L. Merrill, Ariel E. E. Hirsch, Jennifer F. F. Tseng, Teviah E. E. Sachs, Michael R. R. Cassidy
Summary: This study compared the survival outcomes of men with positive sentinel lymph nodes after either sentinel lymph node biopsy (SLNB) alone or complete axillary dissection (ALND) in breast cancer. The results showed that ALND was associated with superior survival compared to SLNB alone in early-stage male breast cancer patients.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Keerthini Muthuswamy, Rebecca Fisher, Stella Mavroveli, Fotis Petrou, Sabrina Khawar, Ashik Amlani, George B. Hanna, Dimitri J. Hadjiminas, Paul T. R. Thiruchelvam, Daniel R. Leff
Summary: A simulator has been designed to safely practice and assess axillary lymph node dissection (ALND), and its face, content, and construct validity has been investigated. The study found that the simulator demonstrated construct validity for ALND assessment and could be a useful tool for skills training and assessments.
Article
Surgery
Prerna Dehariya, Namrata Agarwal, Sanjay Kumar Yadav, Pawan Agarwal, Dhananjaya Sharma
Summary: In this study, we evaluated the impact of topical epinephrine with xylocaine on drainage after axillary lymph node dissection. The results showed that the total drainage volume and duration of drainage were significantly decreased in the epinephrine with xylocaine group compared to the conventional drainage group. The incidence of seroma formation and wound infection was similar in both groups.
WORLD JOURNAL OF SURGERY
(2023)
Article
Oncology
Molly M. Benolken, Sarah McLaughlin, Mara Piltin, Mary Mrdutt, Zhuo Li, James W. Jakub
Summary: This study aimed to determine the frequency of metastatic involvement of an axillary reverse mapping (ARM) lymph node (LN) among patients undergoing axillary lymph node dissection (ALND). Among the 139 patients enrolled, 20% of the patients had a positive ARM LN.
ANNALS OF SURGICAL ONCOLOGY
(2023)