Article
Medicine, General & Internal
Carolyn J. Crandall, Joseph C. Larson, Andrea Z. LaCroix, John A. Robbins, Jean Wactawski-Wende, Karen C. Johnson, Maryam Sattari, Katie L. Stone, Julie C. Weitlauf, Tanya R. Gure, Jane A. Cauley
Summary: This study found that among postmenopausal women over 50 years old, the risk of subsequent fracture was higher regardless of whether the initial fracture was traumatic or nontraumatic. These results suggest that clinical assessments for osteoporosis should consider both high-trauma and low-trauma fractures.
JAMA INTERNAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Kai Liu, Pengwei Jing, Zehan Liu, Ying Wang, Zhu Han, Youqiang Wang, Zhirui Zheng, Yue Wu, Tong Wang, Yuhui Li, Hongying Zhang, Lichun Wang
Summary: This study found that decreased serum levels of circulating irisin are associated with a high risk of osteoporosis-related hip fractures and osteoporosis.
Article
Multidisciplinary Sciences
Kyoung Jin Kim, Namki Hong, Min Heui Yu, Seunghyun Lee, Sungjae Shin, Sin Gon Kim, Yumie Rhee
Summary: This study evaluated the association between GGT levels and the risk of hip fracture in middle-aged women using a Korean claims database. The findings suggest that elevated GGT levels are associated with an increased risk of hip fracture.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Qi Jin, Jinesh Gheeya, Sushma Nepal, Ni Shi, Edmund Folefac, Maxine Z. Webb, Elizabeth M. Grainger, Lai Wei, Jason M. Prosek, Brian C. Focht, Michael Gong, Steven K. Clinton, Fred K. Tabung
Summary: This study examined the association between different dietary quality measures and the risk of kidney cancer. The findings suggest that low-insulinemic dietary patterns and higher quality diets may be beneficial for kidney cancer prevention and improved survivorship.
BRITISH JOURNAL OF CANCER
(2023)
Article
Nutrition & Dietetics
Patricia Paula da Fonseca Grili, Camila Vilarinho Vidigal, Geise Ferreira da Cruz, Ben-Hur Albergaria, Jose Luiz Marques-Rocha, Taisa Sabrina Silva Pereira, Valdete Regina Guandalini
Summary: This study aimed to identify nutrient patterns (NPs) and their association with bone mineral density (BMD) categories in postmenopausal women. The results showed that lower consumption of NP1 and NP2 was associated with an increased risk of osteopenia, but not osteoporosis.
Article
Oncology
Etienne X. Holder, Serena C. Houghton, Sylvia S. Sanchez, A. Heather Eliassen, Jing Qian, Elizabeth R. Bertone-Johnson, Zhenhua Liu, Shelley S. Tworoger, Martyn T. Smith, Susan E. Hankinson
Summary: This study found a positive association between EA and breast cancer risk using a breast cancer cell line-based EA assay. However, the association weakened after accounting for other estrogen levels.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Endocrinology & Metabolism
Anabela Barcelos, Judite Goncalves, Ceu Mateus, Helena Canhao, Ana Maria Rodrigues
Summary: This study reveals that non-hip osteoporosis-related fractures are common among post-menopausal women aged 50+ in Portugal, leading to excessive healthcare costs of over 74 million euros per year.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
Ming Ling, Xianlong Li, Yueyang Xu, Yongqian Fan
Summary: The study revealed that different types of fractures are associated with distinct spatial distributions of hip cortical thickness, with centrally located fractures demonstrating more severe cortical deterioration. This finding should be validated in a larger sample.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Endocrinology & Metabolism
Julien Paccou, Sammy Badr, Daniela Lombardo, Huda Khizindar, Valerie Deken, Stefan Ruschke, Dimitrios C. Karampinos, Anne Cotten, Bernard Cortet
Summary: This study aimed to determine the association between proton density fat fraction (PDFF) and fractures. A case-control study was conducted on postmenopausal women, and it was found that MRI-based measurement of proximal femur PDFF can discriminate between postmenopausal women with and without clinical vertebral fractures, independent of age, CCI, and BMD.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Medicine, Research & Experimental
Qing Wu, Jongyun Jung
Summary: This study introduces a novel genome-wide polygenic score (GPS) to quantify inherited susceptibility to osteoporosis and osteoporotic fracture, providing new opportunities for clinical prevention and risk assessment.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Felicia Baleanu, Michel Moreau, Alexia Charles, Laura Iconaru, Rafik Karmali, Murielle Surquin, Florence Benoit, Aude Mugisha, Marianne Paesmans, Michel Rubinstein, Serge Rozenberg, Pierre Bergmann, Jean-Jacques Body
Summary: This study developed three fracture risk prediction models based on validated clinical risk factors, with acceptable accuracy, particularly for major osteoporotic fractures and central fractures. The study also constructed nomograms for clinical practice.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Oncology
Kara A. Michels, Ashley M. Geczik, Doug C. Bauer, Louise A. Brinton, Diana S. M. Buist, Jane A. Cauley, Cher M. Dallal, Roni T. Falk, Trisha F. Hue, James V. Lacey, Andrea Z. LaCroix, Jeffrey A. Tice, Xia Xu, Britton Trabert
Summary: The study found that progestogens are generally not associated with colorectal cancer risk in postmenopausal women. These findings are consistent with prior research on circulating endogenous sex hormones, suggesting that sex hormones may not be major drivers of colorectal carcinogenesis in postmenopausal women.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Multidisciplinary Sciences
HyunJin Kim, Chung-woo Lee, Myung Ji Nam, Yeon Joo Choi, Kyungdo Han, Jin-Hyung Jung, Do-Hoon Kim, Joo-Hyun Park
Summary: This study found that individuals with obesity have a higher risk of vertebral fracture, especially those with abdominal obesity, regardless of menopausal status.
Article
Oncology
Kristen D. Brantley, Oana A. Zeleznik, Bernard Rosner, Rulla M. Tamimi, Julian Avila-Pacheco, Clary B. Clish, A. Heather Eliassen
Summary: This study explored the association between metabolites and breast cancer risk and found that cholesteryl esters measured earlier in disease etiology were inversely associated with breast cancer, while triacylglycerols with many double bonds measured closer to diagnosis were inversely associated with breast cancer risk.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Public, Environmental & Occupational Health
Ako Adams Ako, Yvonne L. Michael, Lucy F. Robinson, Jean Wactawski-Wende, Aladdin H. Shadyab, Lorena Garcia, Bede N. Nriagu, Nazmus Saquib, Rami Nassir, Simin Liu, Robert B. Wallace
Summary: This study found that postmenopausal women with gallbladder disease have an increased risk of developing type 2 diabetes, especially among those with central obesity. The results support further research to determine whether interventions in older women with gallbladder disease would reduce the risk of type 2 diabetes.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)