Article
Multidisciplinary Sciences
Valeria Garcia-Flores, Roberto Romero, Yi Xu, Kevin Theis, Marcia Arenas-Hernandez, Derek Miller, Azam Peyvandipour, Jose Galaz, Dustyn Levenson, Gaurav Bhatti, Meyer Gershater, Errile Pusod, David Kracht, Violetta Florova, Yaozhu Leng, Li Tao, Megan Faucett, Robert Para, Chaur-Dong Hsu, Gary Zhang, Adi Tarca, Roger Pique-Regi, Nardhy Gomez-Lopez
Summary: This study presents the maternal-fetal immune responses triggered by SARS-CoV-2 infection during pregnancy and highlights the rarity of placental infection. A T-cell dominant inflammatory response is observed at the maternal-fetal interface, but the virus remains undetectable in the placenta while triggering specific immune responses in the neonatal circulation.
NATURE COMMUNICATIONS
(2022)
Article
Medicine, Research & Experimental
Fernanda Lopes Conte, Karen Ingrid Tasca, Karina Basso Santiago, Eliza de Oliveira Cardoso, Graziela Gorete Romagnoli, Marjorie de Assis Golim, Aline Marcia Marques Braz, Andresa Aparecida Berretta, Lenice do Rosario de Souza, Jose Mauricio Sforcin
Summary: This study found that daily intake of propolis by asymptomatic PLWHA under ART may improve immune response and reduce inflammatory status, with a positive correlation between IL-10 levels and CD4+ T cell count observed after treatment.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Virology
Seyit Ahmet Erol, Naci Polat, Sevginur Akdas, Pelin Aribal Ayral, Ali Taner Anuk, Eda Ozden Tokalioglu, Sule Goncu Ayhan, Burcu Kesikli, Merve Nur Ceylan, Atakan Tanacan, Ozlem Moraloglu Tekin, Nuray Yazihan, Dilek Sahin
Summary: This study investigated the selenium status of pregnant women with COVID-19 and found that their serum selenium levels were significantly lower in the second and third trimesters compared to healthy pregnant women. Maternal selenium level was negatively correlated with gestational week, D-dimer, and IL-6 level, while positively correlated with white blood cell, neutrophil, lymphocyte count, and other parameters. Serum selenium level gradually decreased during pregnancy, with a more pronounced decrease in the presence of COVID-19 infection.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Peter Memiah, Lillian Nkinda, Mtebe Majigo, Felix Humwa, Zelalaem Haile, Kennedy Muthoka, Aisha Zuheri, Anne Kamau, Lucy Ochola, Gabriel Buluku
Summary: This study aimed to evaluate the association between mental health symptoms and inflammatory biomarkers in HIV infected individuals. The results indicated that self-reported mental health symptoms were significantly associated with inflammatory markers such as CRP, sTNFR II, and IL-18.
Article
Nutrition & Dietetics
Xiaoming Liu, Xuejiao Zeng, Jinli Mahe, Kai Guo, Panpan He, Qianwen Yang, Zhiwei Zhang, Zhongxia Li, Di Wang, Zheqing Zhang, Lei Wang, Lipeng Jing
Summary: The study found that nattokinase monascus supplements (NMSs) can improve lipid levels, but have no significant effect on serum TG, HDL-C, and CIMT.
Article
Biochemistry & Molecular Biology
Henry J. Thompson, Scot M. Sedlacek, Vanessa K. Fitzgerald, Pamela Wolfe, John N. McGinley
Summary: Damage to cellular macromolecules and changes in insulin-like growth factor metabolic status are intermediate biomarkers of breast cancer risk. A study investigated the potential of selenium supplementation to modulate breast cancer risk and found no evidence to support the hypothesis or indicate an effect on systemic insulin-like growth factor metabolic status.
Article
Microbiology
Joanna Kaczorowska, Aurelija Cicilionyte, Annet Firouzi Wahdaty, Martin Deijs, Maarten F. Jebbink, Margreet Bakker, Lia van der Hoek
Summary: This study found that Anelloviruses (AVs) can potentially be transmitted from mothers to their children through routes other than delivery or breastfeeding, even in the absence of natural birth and breastfeeding.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Emmanuel F. Elia, Jelly Ayungo
Summary: This study found that the socio-demographic characteristics of pregnant women have an impact on their ability to comprehend maternal health information, with education level being particularly significant.
Article
Endocrinology & Metabolism
Lilian Nkinda, Eliud Buberwa, Peter Memiah, Alieth Ntagalinda, Martin George, Frank Msafiri, Agricola Joachim, Mtebe Majigo, Kaushik Ramaiya, Bruno Sunguya
Summary: This study assessed impaired fasting glucose and associated factors among perinatally HIV-infected adolescents and youths in Dar es salaam, Tanzania. The study found that about one in three perinatally HIV-infected youths had impaired fasting glucose, with males bearing the biggest burden. Moreover, the level of interleukin-6 was positively associated with the probability of impaired fasting glucose.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Kehinde S. Okunade, Olusola F. Olowoselu, Sarah John-Olabode, Basirat O. Hassan, Oluwatosin J. Akinsola, Chidinma M. Nwogu, Aloy O. Ugwu, Olusanjo E. Moses, Kabiru A. Rabiu, Adegbenga Ajepe, Muisi A. Adenekan, Adebola A. Adejimi, Sulaimon A. Akanmu, Phyllis J. Kanki
Summary: Selenium supplementation has positive effects on pregnancy outcomes among HIV-infected women, reducing the risk of preterm delivery.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Article
Clinical Neurology
Mathilda Regan, Alfa Muhihi, Arvin Saleh, Christopher P. Duggan, Nzovu Ulenga, Fadhlun M. Alwy Al-Beity, Said Aboud, Wafaie W. Fawzi, Karim P. Manji, Christopher R. Sudfeld
Summary: This study found that approximately 67% of pregnant women living with HIV reported symptoms consistent with depression. The relationship between depression and adverse birth outcomes remains unclear, but interventions are needed to improve the mental health of these women and the health of their infants.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Environmental Sciences
Firoz Abdoel Z. Wahid, Ashna D. Hindori-Mohangoo, Hannah H. Covert, Maryam Karimi, Samain Sabrin, Martin Shafer, Anisma R. Gokoel, Arti Shankar, Wilco Zijlmans, Maureen Lichtveld, Jeffrey K. Wickliffe
Summary: This study assessed the exposure to metals and essential elements in pregnant women in Suriname and found that pregnant women are exposed to levels of mercury and lead that exceed public health concern levels. The findings highlight the importance of developing, implementing, and monitoring environmental health policies.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Seema Vyas, Lameck B. Luwanda, Lorna Guinness, Deborah Kajoka, Prosper Njau, Jenny Renju, Farida Hassan, Alison Wringe
Summary: The study estimated the costs of Option B+ for HIV-infected pregnant women in 12 facilities in Morogoro Region, Tanzania. The average cost per testing episode was US$5.49, the average cost per HIV case detected was US$503.29, and the average cost of neonatal HIV care was US$90.09. The results highlight the need for context-specific cost information for budgeting and planning.
GLOBAL PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Peter M. Chilipweli, Aiwerasia Vera Ngowi, Karim Manji
Summary: Exposure to pesticides among farmworker residents in the SAGCOT area in Tanzania is potentially associated with child developmental effects. Mothers exposed to pesticides are more likely to have children with neurodevelopmental issues.
Article
Obstetrics & Gynecology
Ashish Premkumar, Lynn M. Yee, Lia Benes, Emily S. Miller
Summary: This study aimed to assess the impact of social vulnerability on viral control among foreign-born pregnant women living with HIV. It found that socially-vulnerable women had worse virologic control during pregnancy, with an increased risk of needing more time to achieve viral suppression. However, there was no association with missing doses of antiretroviral therapy or median time to viral suppression.
AMERICAN JOURNAL OF PERINATOLOGY
(2021)