Article
Multidisciplinary Sciences
Mateusz Niedzielski, Marlena Broncel, Paulina Gorzelak-Pabis, Ewelina Wozniak
Summary: The study compared the direct pleiotropic effects of different statins (atorvastatin, rosuvastatin), ezetimibe, and their combinations on endothelial cells damaged by oxidized cholesterol. Results showed that both rosuvastatin and atorvastatin can improve endothelial integrity, but only rosuvastatin can completely abolish the effects of oxidized cholesterol. The combination of statins with ezetimibe has less direct effect on the endothelial barrier than statins alone.
Review
Nutrition & Dietetics
In-Seon Lee, Seok-Jae Ko, Yu Na Lee, Gahyun Lee, Hasanur Rahman, Bonglee Kim
Summary: Metabolic syndrome is a medical condition characterized by abdominal obesity, insulin resistance, high blood pressure, and hyperlipidemia. The brown seaweed Laminaria japonica may have therapeutic effects on metabolic syndrome due to its anti-inflammatory and antioxidant properties.
Review
Pharmacology & Pharmacy
Min Li, Wingyan Yun, Guibin Wang, Anqi Li, Jing Gao, Qingyong He
Summary: The prevention and treatment of cardiovascular diseases (CVDs) have made initial progress, but the number of CVDs patients will rise rapidly in the future. Garlic plays a remarkable role in preventing and treating atherosclerosis (AS), with mechanisms involving lipid-lowering, antioxidant, anti-thrombotic effects, etc. Therefore, the clinical application and mechanistic study of garlic are of great significance.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Maya R. Chilbert, Dylan VanDuyn, Sara Salah, Collin M. Clark, Qing Ma
Summary: Cardiovascular disease is a leading cause of death worldwide. Managing cholesterol, particularly low-density lipoprotein, is an important method for preventing complications. Combination therapy with high-intensity rosuvastatin and ezetimibe has shown potential benefits in reducing cholesterol levels and preventing atherosclerosis.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Medicine, Research & Experimental
Basma S. Mansour, Noha A. Salem, Ghada Abdel Kader, Gamal Abdel-Alrahman, Omayma M. Mahmoud
Summary: The study demonstrated that Rosuvastatin significantly ameliorates the toxic effects of Azithromycin on the heart, including ECG changes, biochemical markers, and oxidative stress. The histological and immunohistochemical results from the Rosuvastatin treated group showed restoration of cardiac muscle fibers, indicating a potential protective effect against Azithromycin-induced cardiotoxicity.
Review
Medicine, General & Internal
Priyal Mehta, Sawsan Tawfeeq, Smitesh Padte, Rayyan Sunasra, Heet Desai, Salim Surani, Rahul Kashyap
Summary: Coronary artery disease (CAD) is a major component of cardiovascular diseases and a leading cause of global mortality. Plant-based diets (PBDs), which promote higher intake of plant foods and lower consumption of animal-based foods, have been shown to reduce the risk of CAD by up to 29% compared to non-vegetarian diets. This article summarizes the different types of PBDs and compares them to conventional Western diets that include meat. It also reviews the proposed mechanisms by which bioactive nutrients in PBDs contribute to the prevention of atherosclerosis and CAD events.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Review
Chemistry, Medicinal
Xiaoning Sun, Bo Jia, Jingran Sun, Jianguo Lin, Bingjiu Lu, Jinlong Duan, Cheng Li, Qingqing Wang, Xin Zhang, Meng Tan, Dongsheng Zhong, Xiaoxiao Zhang, Ziyi Sun, Yan Zhang, Kuiwu Yao
Summary: Gastrodia elata Blume (Tianma) is a valuable herbal Traditional Chinese Medicine commonly used to treat various disorders. Modern pharmacological studies have shown that it possesses diverse pharmacological effects and can be beneficial in cardiovascular diseases.
Review
Automation & Control Systems
Syed Qutaba, Mebrahitom Asmelash, Kushendarsyah Saptaji, Azmir Azhari
Summary: The effects of peening processes on material performance and surface integrity are studied, and the advantages, disadvantages and technological barriers are discussed. The results show that peening processes can improve material performance with potential for industrial applications.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Ali Ahmadi, Tannaz Jamialahmadi, Amirhossein Sahebkar
Summary: This review examines the role of polyphenols in reducing oxidized low-density lipoprotein (oxLDL) and their potential impact on atherosclerosis. While polyphenols show promise as antioxidants, further high-quality studies are needed to fill the gaps in our knowledge.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Pharmacology & Pharmacy
Wenfei Yu, Wei Jiang, Wenjing Wu, Guangyu Wang, Dandan Zhao, Chuanzhu Yan, Pengfei Lin
Summary: This study aimed to investigate the anti-atherosclerotic effect of the combination of idebenone and statins. The results showed that both idebenone and statins reduced plaque burden and increased plaque stability, with the combined treatment showing even better effects. Additionally, the combination therapy also reduced oxidative stress and cell apoptosis. In conclusion, combining idebenone and statins appears to be a promising strategy for further preventing atherosclerosis.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Yuqing Sun, Bo Zhang, Lianghua Xia
Summary: This study aimed to explore the morphological changes of endothelial cells under different levels of shear stress and find effective evaluation indicators through in vivo and in vitro experiments. The results showed that the size and duration of shear stress can affect the morphology and arrangement of endothelial cells. Traditional cell morphological indicators did not show significant statistical significance, while intercellular space characteristics could be used as effective indicators.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Review
Medicine, General & Internal
Tannaz Jamialahmadi, Zeljko Reiner, Mona Alidadi, Wael Almahmeed, Prashant Kesharwani, Khalid Al-Rasadi, Ali H. Eid, Manfredi Rizzo, Amirhossein Sahebkar
Summary: This meta-analysis study showed that bariatric surgery significantly reduced IMT, with the reduction remaining robust in sensitivity analysis. The study did not find a relationship between changes in IMT and changes in BMI or duration of follow-up after bariatric surgery, but subgroup analysis indicated a greater reduction in IMT after laparoscopic sleeve gastrectomy (LSG) compared to Roux-en-Y gastric bypass (RYGB).
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Janine M. Trevillyan, Anthony Dart, Eldho Paul, Matthias Cavassini, Jan Fehr, Cornelia Staehelin, Elizabeth M. Dewar, Jennifer F. Hoy, Alexandra Calmy
Summary: Prescribing statins at a lower threshold than guidelines in PLHIV did not lead to improvements in CIMT but was associated with significant adverse events.
Article
Engineering, Chemical
Ai Wang, Geoffrey Evans, Subhasish Mitra
Summary: In mineral flotation, understanding the dynamics of bubble surface loading (BSL) due to particle attachment and detachment is crucial for the separation kinetics of valuable minerals. This review provides an overview of current techniques for measuring BSL in both quiescent liquid and typical flotation environments. The acoustic emission method shows promise for online measurement in industrial systems, although its implementation has not been satisfactory yet. Challenges remain in estimating the BSL parameter and understanding its impact on the flow field around particle-laden bubbles and the drag coefficient. Coalescence behavior is delayed in the presence of surface loading, leading to the loss of surface energy. Future research should focus on addressing these challenges and finding solutions.
MINERALS ENGINEERING
(2023)
Article
Clinical Neurology
Huaguang Zheng, Hongwei Li, Yilong Wang, Zhanquan Li, Bo Hu, Xiaogang Li, Lu Fu, Hongtao Hu, Zhiyu Nie, Bilian Zhao, Di Wei, Bjorn W. Karlson, Michiel L. Bots, XiangWen Meng, Yundai Chen, Yongjun Wang
Summary: This study demonstrates that rosuvastatin significantly reduces the progression of CIMT in Chinese adults with subclinical atherosclerosis and is well tolerated. The findings contribute to a deeper understanding of atherosclerosis and provide guidance for clinical practice.
Editorial Material
Clinical Neurology
Paul L. McCormack, Dean M. Robinson
Article
Pharmacology & Pharmacy
Monique P. Curran, Dean M. Robinson
Article
Pharmacology & Pharmacy
Greg L. Plosker, Dean M. Robinson
Article
Pharmacology & Pharmacy
Greg L. Plosker, Dean M. Robinson
Review
Pharmacology & Pharmacy
Monique P. Curran, Dean M. Robinson
Article
Physiology
S. P. Cairns, D. M. Robinson, D. S. Loiselle
EXPERIMENTAL PHYSIOLOGY
(2008)
Article
Neurosciences
G. D. Funk, J. D. Zwicker, R. Selvaratnam, D. M. Robinson
ARCHIVES ITALIENNES DE BIOLOGIE
(2011)
Article
Neurosciences
Amanda R. Lorier, Adrianne G. Huxtable, Dean M. Robinson, Janusz Lipski, Gary D. Housley, Gregory D. Funk
JOURNAL OF NEUROSCIENCE
(2007)
Correction
Pharmacology & Pharmacy
M. P. Curran, D. M. Robinson
Review
Cardiac & Cardiovascular Systems
Dean M. Robinson, Gillian M. Keating
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
(2007)
Correction
Clinical Neurology
D. M. Robinson, G. M. Keating
Article
Clinical Neurology
Dean M. Robinson, Gillian M. Keating
Review
Pharmacology & Pharmacy
Dean M. Robinson, Monigue P. Curran, Katherine A. Lyseng-Williamson
Article
Pharmacology & Pharmacy
Paul L. McCormack, Dean M. Robinson, Caroline M. Perry