Article
Multidisciplinary Sciences
Peerapat Kaveevorayan, Nithi Tokavanich, Veraprapas Kittipibul, Thana Lertsuttimetta, Seri Singhatanadgige, Pat Ongcharit, Supanee Sinphurmsukskul, Aekarach Ariyachaipanich, Sarawut Siwamogsatham, Kanokwan Thammanatsakul, Supaporn Sritangsirikul, Sarinya Puwanant
Summary: This study aimed to determine the prevalence, characteristics, and outcomes of primary isolated right ventricular failure (PI-RVF) after heart transplant (HTX). PI-RVF can be diagnosed within 24-72 hours after completion of heart transplantation. The study found that 59% of patients developed PI-RVF, with 48% meeting the criteria for PGD-RV. Severe RV failure was associated with increased rates of 30-day mortality and post-operative dialysis, while moderate RV failure was associated with post-operative dialysis.
SCIENTIFIC REPORTS
(2023)
Review
Cardiac & Cardiovascular Systems
Alessio Gasperetti, Cynthia A. James, Marina Cerrone, Mario Delmar, Hugh Calkins, Firat Duru
Summary: Physical exercise can influence the progression and arrhythmia risk of arrhythmogenic right ventricular cardiomyopathy (ARVC), guidelines currently recommend individuals with ARVC to avoid competitive or high-intensity endurance exercise, as exercise-induced physiological changes may mimic classic features of ARVC.
EUROPEAN HEART JOURNAL
(2021)
Article
Pediatrics
Tao Qian, Zhong-Shi Wu, Jian-Guo Hu, Yi-Feng Yang, Qin Wu, Ting Lu, Can Huang, Jia Li
Summary: DP-BJVC provides satisfactory durability and functionality for RVOT reconstruction for children, with low morbidity of stenosis and endocarditis, as well as a mild increase in diameter with age in midterm follow-ups.
FRONTIERS IN PEDIATRICS
(2021)
Article
Cardiac & Cardiovascular Systems
Catherine G. Ireland, Rachel L. Damico, Todd M. Kolb, Stephen C. Mathai, Monica Mukherjee, Stefan L. Zimmerman, Ami A. Shah, Fredrick M. Wigley, Brian A. Houston, Paul M. Hassoun, David A. Kass, Ryan J. Tedford, Steven Hsu
Summary: The study found that measuring RV contractile reserve during exercise by changes in RV Ees and dilation can better predict occult RV dysfunction, with RV ejection fraction during exercise proving to be a robust surrogate. This parameter was found to predict clinical outcomes more effectively than resting measures of RV function.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2021)
Article
Cardiac & Cardiovascular Systems
Alexander C. Egbe, William R. Miranda, Patricia A. Pellikka, Christopher DeSimone, Heidi M. Connolly
Summary: The study aimed to determine the prevalence, risk factors, and prognostic implications of left ventricular systolic dysfunction (LVSD) in adults with congenital heart disease (CHD). The results showed that 12% of patients had LVSD, which was more common in right-sided lesions compared to left-sided lesions. Cardiovascular events occurred in 7% of patients and were associated with left ventricular ejection fraction (LVEF). Guideline-directed medical therapy (GDMT) and cardiac resynchronization therapy (CRT) were found to improve LVEF.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Garrett N. Coyan, Luciana Da Fonseca Da Silva, Jose P. Da Silva, Melita Viegas, Victor O. Morell, Mario Castro-Medina
Summary: This study presents a technique for constructing a handmade tricuspid valved polytetrafluoroethylene conduit for patients of all ages requiring right ventricular outflow tract reconstruction. The conduit provides an economically advantageous and readily available option globally, without sacrificing surgical results.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Julia Cadrin-Tourigny, Laurens P. Bosman, Anna Nozza, Weijia Wang, Rafik Tadros, Aditya Bhonsale, Mimount Bourfiss, Annik Fortier, Oyvind H. Lie, Ardan M. Saguner, Anneli Svensson, Antoine Andorin, Crystal Tichnell, Brittney Murray, Katja Zeppenfeld, Maarten P. van den Berg, Folkert W. Asselbergs, Arthur A. M. Wilde, Andrew D. Krahn, Mario Talajic, Lena Rivard, Stephen Chelko, Stefan L. Zimmerman, Ihab R. Kamel, Jane E. Crosson, Daniel P. Judge, Sing-Chien Yap, Jeroen F. van der Heijden, Harikrishna Tandri, Jan D. H. Jongbloed, Marie-Claude Guertin, J. Peter van Tintelen, Pyotr G. Platonov, Firat Duru, Kristina H. Haugaa, Paul Khairy, Richard N. W. Hauer, Hugh Calkins, Anneline S. J. M. te Riele, Cynthia A. James
Summary: We developed a prediction model for incident VA/SCD in ARVC patients using readily available clinical parameters, which accurately distinguished patients with and without events and showed superior clinical benefit compared to current ICD placement algorithms.
EUROPEAN HEART JOURNAL
(2022)
Review
Biotechnology & Applied Microbiology
Chenggang Li, Bo Xie, Ruizhe Tan, Lijin Liang, Zhaoxiang Peng, Qi Chen
Summary: This review discusses the complications associated with bovine jugular vein conduit (BJVC) in right ventricular outflow tract (RVOT) reconstruction surgery and summarizes the current technological advancements. Novel crosslinking agents, decellularization techniques, conduit coatings, and physical reinforcement materials have improved the performance of BJVCs. The authors believe that breakthroughs in BJVC's clinical application may come from new genetic research findings and advanced characterization apparatuses and bioreactors, and they are optimistic about BJVC's potential in providing sophisticated therapies for next-generation RVOT reconstruction.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Paloma Jorda, Laurens P. Bosman, Alessio Gasperetti, Andrea Mazzanti, Jean-Baptiste Gourraud, Brianna Davies, Tanja Charlotte Frederiksen, Zoraida Moreno Weidmann, Andrea Di Marco, Jason D. Roberts, Ciorsti MacIntyre, Colette Seifer, Antoine Deliniere, Wael Alqarawi, Deni Kukavica, Damien Minois, Alessandro Trancuccio, Marine Arnaud, Mattia Targetti, Annamaria Martino, Giada Oliviero, Daniel C. Pipilas, Corrado Carbucicchio, Paolo Compagnucci, Antonio Dello Russo, Iacopo Olivotto, Leonardo Calo, Steven A. Lubitz, Michael J. Cutler, Philippe Chevalier, Elena Arbelo, Silvia Giuliana Priori, Jeffrey S. Healey, Hugh Calkins, Michela Casella, Henrik Kjaerulf Jensen, Claudio Tondo, Rafik Tadros, Cynthia A. James, Andrew D. Krahn, Julia Cadrin-Tourigny
Summary: This study validated a 5-year risk prediction model for ARVC patients, demonstrating its superior performance in guiding ICD implantation decisions compared to other published guidelines and consensus statements. The findings support the use of this model for shared decision making in the primary prevention of SCD in ARVC patients.
EUROPEAN HEART JOURNAL
(2022)
Review
Cardiac & Cardiovascular Systems
Sayed Al-Aidarous, Alexandros Protonotarios, Perry M. Elliott, Pier D. Lambiase
Summary: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease characterized by myocardial fibrofatty replacement due to specific mutations, resulting in ventricular arrhythmias and sudden cardiac death. Treating this condition is challenging due to fibrosis progression, phenotypic variations, and limited clinical trials. While beta-blockers are theoretically effective, their efficacy in reducing arrhythmic risk is not strong. Emerging evidence suggests that combining flecainide and bisoprolol may be effective. Radiofrequency ablation and stereotactic radiotherapy show potential in disrupting ventricular circuits and modifying myocardial fibrosis. Future therapies, such as adenoviruses and GSk3b modulation, are still in early-stage research. Implantable cardioverter-defibrillator implantation reduces arrhythmic death but comes with risks.
Article
Cardiac & Cardiovascular Systems
Hiroto Utsunomiya, Kanako Izumi, Akane Tsuchiya, Atsuo Mogami, Kosuke Takahari, Hajime Takemoto, Erasta Ramandika, Yusuke Ueda, Kiho Itakura, Yukiko Nakano
Summary: This study proposed a novel risk stratification system for severe tricuspid regurgitation and validated its prognostic significance. The findings showed that a large 3D-AROA and reduced right ventricular contractile reserve during exercise were independently associated with poor prognosis.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tilman Emrich, Veronica Bordonaro, U. Joseph Schoepf, Aniela Petrescu, Gabrielle Young, Moritz Halfmann, Theresia Schoeler, Josua Decker, Ibukun Abidoye, Anna Lena Emrich, Karl-Friedrich Kreitner, Kai Helge Schmidt, Akos Varga-Szemes, Aurelio Secinaro
Summary: The study aimed to test the feasibility of T2 mapping for detecting left-to-right shunts. Results indicated that the T2 ratio can serve as an imaging biomarker capable of detecting or ruling out left-to-right shunts.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Gherardo Finocchiaro, Barbara Barra, Silvia Molaro, Mattia Zampieri, Laura Monje-Garcia, Colin Evans, Andrea Ermolao, Georgios Georgiopoulos, Nabeel Sheikh, Rachel Bastiaenen, Leema Roberts, Pier-Giorgio Masci, Dan Sado, Amedeo Chiribiri, Gerald Carr-White
Summary: The study found that ARVC patients are prone to exercise-induced arrhythmias, with those with more significant right ventricular remodeling and left ventricular involvement being more susceptible to exercise-induced arrhythmias.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Review
Multidisciplinary Sciences
Christophe Dongmo Fokoua-Maxime, Armel Jackson Seukep, Yahia Bellouche, Takeude Erwan Cheuffa-Karel, Dickson Shey Nsagha, Francois Folefack Kaze
Summary: This study aims to fill the gap in knowledge regarding the global prevalence of silent myocardial ischemia (SMI) in CKD patients. Eligible studies will be identified through systematic literature search and rigorous screening process, followed by robust meta-analysis tools to provide reliable estimates of the global prevalence of SMI in CKD patients.
Editorial Material
Cardiac & Cardiovascular Systems
Yosuke Kugo, Masaki Taira, Takuji Watanabe, Yuji Tominaga, Moyu Hasegawa, Takayoshi Ueno, Shigeru Miyagawa
Summary: This article reports a case of a 14-year-old boy with prolonged right ventricular dysfunction due to postmyocarditis cardiomyopathy, while left ventricular function recovered with conservative treatment. Despite one-and-a-half ventricle repair, RV dilation continued to worsen, so RV exclusion and extracardiac total cavopulmonary connection were performed 3 years after the operation. Postoperatively, left ventricular function was maintained and no further RV dilation was observed. Univentricular conversion may be an effective procedure for the treatment of acquired severe isolated right-sided heart failure.
ANNALS OF THORACIC SURGERY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)