Article
Cardiac & Cardiovascular Systems
Guglielmo Gallone, Jeehoon Kang, Francesco Bruno, Jung-Kyu Han, Ovidio De Filippo, Han-Mo Yang, Mattia Doronzo, Kyung-Woo Park, Gianluca Mittone, Hyun-Jae Kang, Radoslaw Parma, Hyeon-Cheol Gwon, Enrico Cerrato, Woo Jung Chun, Grzegorz Smolka, Seung-Ho Hur, Gerard Helft, Seung Hwan Han, Saverio Muscoli, Young Bin Song, Filippo Figini, Ki Hong Choi, Giacomo Boccuzzi, Soon-Jun Hong, Daniela Trabattoni, Chang-Wook Nam, Massimo Giammaria, Hyo-Soo Kim, Federico Conrotto, Javier Escaned, Carlo Di Mario, Fabrizio D'Ascenzo, Bon-Kwon Koo, Gaetano Maria de Ferrari
Summary: The association between left ventricular ejection fraction (LVEF) and outcomes of percutaneous coronary intervention (PCI) for bifurcation lesions is still uncertain. This study found that reduced LVEF (<40%) is a strong predictor of long-term major adverse cardiac events (MACEs), but does not affect procedural outcomes.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitri Karmpaliotis, Amirali Masoumi, Farouc A. Jaffer, Darshan Doshi, Jaikirshan Khatri, Paul Poommipanit, Sevket Gorgulu, Omer Goktekin, Oleg Krestyaninov, Rhian Davies, Ahmed ElGuindy, Brian K. Jefferson, Taral N. Patel, Mitul Patel, Raj H. Chandwaney, Kambis Mashayekhi, Alfredo R. Galassi, Bavana Rangan, Emmanouil S. Brilakis
Summary: The relationship between left ventricular ejection fraction (LVEF) and the success and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI) was studied. The study found that in patients with reduced LVEF, although percutaneous intervention had a high technical success rate, it was associated with higher in-hospital and post-discharge mortality.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Valentino Bianco, Arman Kilic, Suresh Mulukutla, Thomas G. Gleason, Dustin Kliner, Christopher C. Allen, Andreas Habertheuer, Edgar Aranda-Michel, Rishab Humar, Forozan Navid, Yisi Wang, Ibrahim Sultan
Summary: Comparative outcomes for patients with reduced ejection fraction undergoing CABG vs PCI showed that CABG was associated with improved long-term survival, reduced MACCE events, and fewer repeat revascularization procedures.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Health Care Sciences & Services
Federico Marin, Michele Pighi, Federico Zucchelli, Alessandro Ruzzarin, Giulio Russo, Cristina Aurigemma, Enrico Romagnoli, Valeria Ferrero, Anna Piccoli, Roberto Scarsini, Gabriele Pesarini, Carlo Trani, Francesco Burzotta, Flavio Luciano Ribichini
Summary: This study aims to assess the predictors and prognostic role of left ventricle ejection fraction (LVEF) recovery after Impella-supported PCI in patients with acute myocardial infarction (AMI). The study found that complete functional revascularization is an independent predictor of LVEF recovery, and the recovery of LV function is associated with improved prognosis.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Sebastian Rosch, Karl-Patrik Kresoja, Christian Besler, Karl Fengler, Anne Rebecca Schoeber, Maximilian von Roeder, Christian Luecke, Matthias Gutberlet, Karin Klingel, Holger Thiele, Karl-Philipp Rommel, Philipp Lurz
Summary: In this study, patients with heart failure with preserved ejection fraction (HFpEF) were stratified based on left ventricular ejection fraction (LVEF), resulting in distinct morphologic and pathophysiologic subphenotypes. Patients with LVEF ranging from 50% to 60% demonstrated reduced contractility, impaired ventriculo-arterial coupling, and higher extracellular volume fraction, while patients with LVEF >60% exhibited a hypercontractile state with excessive left ventricular afterload and diminished preload reserve.
Article
Cardiac & Cardiovascular Systems
Xinxin Zhang, Yuxi Sun, Yanli Zhang, Feifei Chen, Shuyuan Zhang, Hongyan He, Shuang Song, Gary Tse, Ying Liu
Summary: This study found that HFmrEF patients are heterogeneous with three different subsets identified, each with different outcomes. The association between change in LVEF and adverse outcomes remained significant even after fully adjusting for all-cause mortality and composite outcome. Strategies for managing HFmrEF should include previously measured LVEF to allow stratification based on direction changes in LVEF for better treatment optimization.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Biology
Diana-Aurora Arnautu, Minodora Andor, Bogdan-Flaviu Buz, Mirela-Cleopatra Tomescu, Cristina Vacarescu, Simina Crisan, Dan Gaita, Constantin-Tudor Luca, Dragos Cozma
Summary: Patients with acute myocardial infarction (AMI) are at risk of heart failure (HF) even after successful revascularization therapy. A study identified early predictors of HF after AMI and found that age, hypertension, smoking, and severe clinical presentations of AMI were associated with HF. The presence of HF at admission and abnormal deformation patterns of the infarct-related myocardial segments detected by echocardiography accurately predicted the occurrence of HF in the next two years.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ping Wu, Xiaoli Zhang, Zhifang Wu, Huanzhen Chen, Xiaoshan Guo, Chunrong Jin, Gang Qin, Ruonan Wang, Hongliang Wang, Qiting Sun, Li Li, Rui Yan, Xiang Li, Marcus Hacker, Sijin Li
Summary: A recent study found a U-shaped hazard ratio curve between resting left ventricular ejection fraction (LVEF) and prognosis in patients with routine clinical echocardiograms. This study aimed to investigate whether a similar U-shaped curve existed between resting LVEF and coronary flow reserve (CFR) in patients without severe cardiovascular disease (CVD). The results showed that patients with supra-normal LVEF (snLVEF) and reduced LVEF (rLVEF) were more likely to have reduced CFR compared to those with normal LVEF (nLVEF). Patients with snLVEF also had a higher incidence of major adverse cardiac events (MACE).
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Medicine, General & Internal
Andrzej Minczykowski, Marcin Zwanzig, Mateusz Dziarmaga, Agnieszka Rutkowska, Marek Balinski, Tomasz Krauze, Przemyslaw Guzik, Andrzej Wykretowicz
Summary: Left ventricular systolic function can be assessed using echocardiography with parameters such as LV ejection fraction (LVEF) or global longitudinal peak systolic strain (GLPSS). Newer indices, including global wasted work (GWW), global work efficiency (GWE), and first-phase ejection fraction (LVEF-1), were examined in healthy individuals and patients with stable coronary artery disease (CAD). The results showed that CAD patients had similar LVEF but higher GLPSS and GWW, and lower GWE and LVEF-1 compared to healthy individuals. LVEF-1 was found to have the highest diagnostic accuracy for detecting CAD.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Yusuke Adachi, Arihiro Kiyosue, Jiro Ando, Takuya Kawahara, Satoshi Kodera, Shun Minatsuki, Hironobu Kikuchi, Toshiro Inaba, Hiroyuki Kiriyama, Kazutoshi Hirose, Hiroki Shinohara, Akihito Saito, Takayuki Fujiwara, Hironori Hara, Kazutaka Ueda, Kenichi Sakakura, Masaru Hatano, Mutsuo Harada, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Shin-Ichi Momomura, Hideo Fujita, Issei Komuro
Summary: Determinants of left ventricular reverse remodelling (LVRR) following PCI in CAD patients with reduced LVEF include factors such as unprotected left main coronary artery (LMCA) intervention, prior PCI, presence of in-stent restenosis, and presence of de-novo stenosis. These data indicate the potential prognostic benefit of unprotected LMCA intervention for LVRR and the importance of angiographic follow-up in patients with CAD and LV systolic dysfunction.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Hyun Sung Joh, Doosup Shin, Joo Myung Lee, Seung Hun Lee, David Hong, Ki Hong Choi, Doyeon Hwang, Coen K. M. Boerhout, Guus A. de Waard, Ji-Hyun Jung, Hernan Mejia-Renteria, Masahiro Hoshino, Mauro Echavarria-Pinto, Martijn Meuwissen, Hitoshi Matsuo, Maribel Madera-Cambero, Ashkan Eftekhari, Mohamed A. Effat, Tadashi Murai, Koen Marques, Joon-Hyung Doh, Evald H. Christiansen, Rupak Banerjee, Hyun Kuk Kim, Chang-Wook Nam, Giampaolo Niccoli, Masafumi Nakayama, Nobuhiro Tanaka, Eun-Seok Shin, Steven A. J. Chamuleau, Niels van Royen, Paul Knaapen, Bon Kwon Koo, Tsunekazu Kakuta, Javier Escaned, Jan J. Piek, Tim P. van de Hoef
Summary: This study evaluated the association and prognostic implications of intracoronary physiologic indexes and left ventricular ejection fraction (LVEF) in patients with coronary artery disease. The results showed that reduced coronary flow reserve (CFR) increased the risk of target vessel failure regardless of LVEF.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Lulu Yang, Huan Li, Guangli Guo, Jiaqi Du, Zhengyang Hao, Lingyao Kong, Huiting Shi, Xiaofang Wang, Yanzhou Zhang
Summary: This study aimed to develop a simple and easy-to-use model for predicting the occurrence of heart failure with improved left ventricular ejection fraction (HFiEF) in patients who underwent percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). The researchers identified age, previous myocardial infarction, left ventricular end-diastolic dimension, and sodium glucose cotransporter two inhibitors as predictors of HFiEF. A reliable nomogram was established to predict the incidence of HFiEF.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Brian P. Halliday, Roxy Senior, Dudley J. Pennell
Summary: The measurement of left ventricular ejection fraction (LVEF) has been a key component in imaging studies for cardiac patients, but its utility as a prognostic indicator has diminished in certain populations such as heart failure patients with preserved ejection fraction (HF-PEF) and those with valvular heart disease. Assessing myocardial strain, particularly global longitudinal strain (GLS), holds promise in improving risk stratification and therapy selection for these patients. Additional studies are needed to fully integrate GLS into routine clinical practice and improve patient outcomes.
EUROPEAN HEART JOURNAL
(2021)
Review
Cardiac & Cardiovascular Systems
Brian P. Halliday, Roxy Senior, Dudley J. Pennell
Summary: Traditional methods of assessing cardiac function like LVEF are no longer accurate in predicting prognosis for heart failure patients, highlighting the need for better indicators such as GLS to improve risk stratification and accuracy of disease assessment. For patients with heart failure and valvular heart disease, GLS may be a superior option to consider.
EUROPEAN HEART JOURNAL
(2021)
Article
Medicine, General & Internal
Jason Stencel, Hamid R. Alai, Aneesh Dhore-patil, Daniela Urina-Jassir, Thierry H. Le Jemtel
Summary: Preserved ejection fraction heart failure in obese individuals has become common in clinical practice due to the obesity epidemic. It is challenging to determine if obesity enables the development of preserved ejection fraction heart failure or if it is a convergence of two prevalent conditions. However, the obese phenotype of preserved ejection fraction heart failure provides an opportunity to study the effects of bariatric surgery on reversing left ventricular remodeling.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Nobuaki Kobayashi, Akiko Maehara, Sorin J. Brener, Philippe Genereux, Bernhard Witzenbichler, Giulio Guagliumi, Jan Z. Peruga, Roxana Mehran, Gary S. Mintz, Gregg W. Stone
AMERICAN JOURNAL OF CARDIOLOGY
(2015)
Article
Cardiac & Cardiovascular Systems
Peiren Shan, Gary S. Mintz, Bernhard Witzenbichler, D. Christopher Metzger, Michael J. Rinaldi, Peter L. Duffy, Giora Weisz, Thomas D. Stuckey, Bruce R. Brodie, Philippe Genereux, Aaron Crowley, Ajay J. Kirtane, Gregg W. Stone, Akiko Maehara
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2017)
Article
Cardiac & Cardiovascular Systems
Philippe Genereux, Bjorn Redfors, Bernhard Witzenbichler, Marie-Pier Arsenault, Giora Weisz, Thomas D. Stuckey, Michael J. Rinaldi, Franz-Josef Neumann, D. Christopher Metzger, Timothy D. Henry, David A. Cox, Peter L. Duffy, Ernest L. Mazzaferri, Dominic P. Francese, Guillaume Marquis-Gravel, Gary S. Mintz, Ajay J. Kirtane, Akiko Maehara, Roxana Mehran, Gregg W. Stone
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2017)
Article
Cardiac & Cardiovascular Systems
Mahesh V. Madhavan, Philippe Genereux, Ajay J. Kirtane, Ke Xu, Bernhard Witzenbichler, Roxana Mehran, Gregg W. Stone
AMERICAN JOURNAL OF CARDIOLOGY
(2014)
Article
Cardiac & Cardiovascular Systems
Sorin J. Brener, Keith G. Oldroyd, Akiko Maehara, Magdi El-Omar, Bernhard Witzenbichler, Ke Xu, Roxana Mehran, Michael Gibson, Gregg W. Stone
AMERICAN JOURNAL OF CARDIOLOGY
(2014)
Article
Cardiac & Cardiovascular Systems
Elias A. Sanidas, Sorin J. Brener, Akiko Maehara, Philippe Genereux, Bernhard Witzenbichler, Magdi El-Omar, Martin Fahy, Roxana Mehran, C. Michael Gibson, Gregg W. Stone
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2014)
Article
Cardiac & Cardiovascular Systems
Bernhard Witzenbichler, Akiko Maehara, Giora Weisz, Franz-Josef Neumann, Michael J. Rinaldi, D. Christopher Metzger, Timothy D. Henry, David A. Cox, Peter L. Duffy, Bruce R. Brodie, Thomas D. Stuckey, Ernest L. Mazzaferri, Ke Xu, Helen Parise, Roxana Mehran, Gary S. Mintz, Gregg W. Stone
Article
Cardiac & Cardiovascular Systems
David Planer, Bernhard Witzenbichler, Giulio Guagliumi, Jan Z. Peruga, Bruce R. Brodie, Ke Xu, Martin Fahy, Roxana Mehran, Gregg W. Stone
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2013)
Article
Cardiac & Cardiovascular Systems
Wouter J. Kikkert, Bimmer E. Claessen, Gregg W. Stone, Roxana Mehran, Bernhard Witzenbichler, Bruce R. Brodie, Jochen Woehrle, Adam Witkowski, Giulio Guagliumi, Krzysztof Zmudka, Jose P. S. Henriques, Jan G. P. Tijssen, Elias A. Sanidas, Vasiliki Chantziara, Ke Xu, George D. Dangas
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2014)
Article
Cardiac & Cardiovascular Systems
Ralph Toelg, Bela Merkely, Andrejs Erglis, Stefan Hoffman, Huret Bruno, Ran Kornowski, Ton Slagboom, Christoph Naber, Bernhard Witzenbichler, Kristof Graf, Gert Richardt, Christoph Hehrlein
Article
Cardiac & Cardiovascular Systems
Gjin Ndrepepa, Franz-Josef Neumann, Maurizio Menichelli, Isabell Bernlochner, Gert Richardt, Jochen Woehrle, Bernhard Witzenbichler, Katharina Mayer, Salvatore Cassese, Senta Gewalt, Erion Xhepa, Sebastian Kufner, Hendrik B. Sager, Michael Joner, Tareq Ibrahim, Karl-Ludwig Laugwitz, Heribert Schunkert, Stefanie Schuepke, Adnan Kastrati
Summary: Patients recruited in a low recruitment center (LRC) for acute coronary syndrome appear to have more favorable cardiovascular risk profiles and lower 1-year mortality rates compared with those recruited in a high recruitment center (HRC). The recruitment volume did not interact with the treatment effect of ticagrelor versus prasugrel.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Shqipdona Lahu, Gjin Ndrepepa, Franz-Josef Neumann, Maurizio Menichelli, Isabell Bernlochner, Gert Richardt, Jochen Wohrle, Bernhard Witzenbichler, Rayyan Hemetsberger, Katharina Mayer, Ibrahim Akin, Salvatore Cassese, Senta Gewalt, Erion Xhepa, Sebastian Kufner, Christian Valina, Hendrik B. Sager, Michael Joner, Tareq Ibrahim, Karl-Ludwig Laugwitz, Heribert Schunkert, Stefanie Schupke, Adnan Kastrati
Summary: Pre-admission treatment with aspirin and/or clopidogrel does not affect the efficacy and safety of ticagrelor and prasugrel in patients with acute coronary syndromes.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2022)
Article
Cardiac & Cardiovascular Systems
Shqipdona Lahu, Antonia Presch, Gjin Ndrepepa, Maurizio Menichelli, Christian Valina, Rayyan Hemetsberger, Bernhard Witzenbichler, Isabell Bernlochner, Michael Joner, Erion Xhepa, Alexander Hapfelmeier, Sebastian Kufner, Nonglag Rifatov, Hendrik B. Sager, Katharina Mayer, Thorsten Kessler, Karl-Ludwig Laugwitz, Gert Richardt, Heribert Schunkert, Franz-Josef Neumann, Dirk Sibbing, Dominick J. Angiolillo, Adnan Kastrati, Salvatore Cassese
Summary: This study aimed to compare the efficacy and safety of ticagrelor and prasugrel in acute coronary syndrome patients with high bleeding risk undergoing percutaneous coronary intervention. The results showed that HBR status increased the risk of ischemic and bleeding events in these patients, but there was no significant difference in the treatment effect between ticagrelor and prasugrel. Further studies are needed for confirmation.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Shqipdona Lahu, Maria Scalamogna, Gjin Ndrepepa, Maurizio Menichelli, Christian Valina, Rayyan Hemetsberger, Bernhard Witzenbichler, Isabell Bernlochner, Michael Joner, Erion Xhepa, Alexander Hapfelmeier, Sebastian Kufner, Hendrik B. Sager, Katharina Mayer, Thorsten Kessler, Karl-Ludwig Laugwitz, Gert Richardt, Heribert Schunkert, Franz-Josef Neumann, Adnan Kastrati, Salvatore Cassese
Summary: This study compares the efficacy and safety of ticagrelor and prasugrel in patients with acute coronary syndrome and prior myocardial infarction (MI). The results show that prasugrel is superior to ticagrelor in reducing the risk of recurrent ischemic events without increasing the risk of bleeding.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Bahira Shahim, Bjorn Redfors, Thomas D. Stuckey, Mengdan Liu, Zhipeng Zhou, Bernhard Witzenbichler, Giora Weisz, Michael J. Rinaldi, Franz-Josef Neumann, D. Christopher Metzger, Timothy D. Henry, David A. Cox, Peter L. Duffy, Bruce R. Brodie, Iva Srdanovic, Mahesh Madhavan, Ernest L. Mazzaferri, Roxana Mehran, Ori Ben-Yehuda, Ajay J. Kirtane, Gregg W. Stone
Summary: Diabetes mellitus and high platelet reactivity (HPR) are both associated with increased risk of ischemic events after percutaneous coronary intervention. However, it is unknown whether the HPR-related risk of adverse ischemic events differs according to diabetes mellitus status.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)