Effects of the Cyclooxygenase Inhibiting Nitric Oxide Donator Naproxcinod Versus Naproxen on Systemic Blood Pressure in Patients With Osteoarthritis††Conflicts of interest: Dr. White reports receiving research support during the past 12 months from the National Institutes of Health, Bethesda, Maryland; the Catherine and Patrick Donaghue Medical Research Foundation, West Hartford, Connecticut; the American Heart Association, Dallas, Texas; and Novartis Pharmaceuticals Corporation, East Hanover, New Jersey. Dr. White presently serves as a safety consultant to Gilead Sciences, Inc., Foster City, California; Myriad Genetics, Inc., Salt Lake City, Utah; NicOx S.A., Sophia-Antipolis, France; Takeda Research and Development Group, Deerfield, Illinois; and Teva Neuroscience, Inc., Kansas City, Missouri. Dr. Schnitzer reports receiving research support from the National Institutes of Health; Pfizer Laboratories, Inc., New York, New York; Wyeth Laboratories, Madison, New Jersey; Nordic Bioscience, Herlev, Denmark; Novartis Pharmaceuticals Corporation; Genzyme Corporation, Cambridge, Massachusetts; and Pozen, Inc., Chapel Hill, North Carolina. Dr. Schnitzer presently serves as a consultant to Logical Therapeutics, Inc., Waltham, Massachusetts; NicOx, Inc., Warren, New Jersey; Merck & Company, Inc., Whitehouse Station, New Jersey; SantoSolve AS, Oslo, Norway; Solstice Neurosciences, South San Francisco, California; and Horizon Therapeutics, Northbrook, Illinois. Dr. Schnitzer is a noninvested shareholder of NicOx S.A. Mrs. Fleming is an employee of NicOx, Inc. Drs. Duquesroix and Beekman are employees of NicOx, S.A.

Title

Effects of the Cyclooxygenase Inhibiting Nitric Oxide Donator Naproxcinod Versus Naproxen on Systemic Blood Pressure in Patients With Osteoarthritis††Conflicts of interest: Dr. White reports receiving research support during the past 12 months from the National Institutes of Health, Bethesda, Maryland; the Catherine and Patrick Donaghue Medical Research Foundation, West Hartford, Connecticut; the American Heart Association, Dallas, Texas; and Novartis Pharmaceuticals Corporation, East Hanover, New Jersey. Dr. White presently serves as a safety consultant to Gilead Sciences, Inc., Foster City, California; Myriad Genetics, Inc., Salt Lake City, Utah; NicOx S.A., Sophia-Antipolis, France; Takeda Research and Development Group, Deerfield, Illinois; and Teva Neuroscience, Inc., Kansas City, Missouri. Dr. Schnitzer reports receiving research support from the National Institutes of Health; Pfizer Laboratories, Inc., New York, New York; Wyeth Laboratories, Madison, New Jersey; Nordic Bioscience, Herlev, Denmark; Novartis Pharmaceuticals Corporation; Genzyme Corporation, Cambridge, Massachusetts; and Pozen, Inc., Chapel Hill, North Carolina. Dr. Schnitzer presently serves as a consultant to Logical Therapeutics, Inc., Waltham, Massachusetts; NicOx, Inc., Warren, New Jersey; Merck & Company, Inc., Whitehouse Station, New Jersey; SantoSolve AS, Oslo, Norway; Solstice Neurosciences, South San Francisco, California; and Horizon Therapeutics, Northbrook, Illinois. Dr. Schnitzer is a noninvested shareholder of NicOx S.A. Mrs. Fleming is an employee of NicOx, Inc. Drs. Duquesroix and Beekman are employees of NicOx, S.A.

Authors

Keywords

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Journal

AMERICAN JOURNAL OF CARDIOLOGY

Volume 104, Issue 6, Pages 840-845

Publisher

Elsevier BV

Online

2009-09-05

DOI

10.1016/j.amjcard.2009.05.014