Review
Cardiac & Cardiovascular Systems
Patrick W. Serruys, Hironori Hara, Scot Garg, Hideyuki Kawashima, Bjarne L. Norgaard, Marc R. Dweck, Jeroen J. Bax, Juhani Knuuti, Koen Nieman, Jonathon A. Leipsic, Saima Mushtaq, Daniele Andreini, Yoshinobu Onuma
Summary: Coronary computed tomography angiography (CTA) has undergone significant technological advancements and is now considered a high-accuracy substitute for conventional invasive coronary angiography in diagnosing and making treatment decisions for patients with suspected coronary artery disease.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yiming Li, Yu Wu, Jingjing He, Weili Jiang, Jianyong Wang, Yong Peng, Yuheng Jia, Tianyuan Xiong, Kaiyu Jia, Zhang Yi, Mao Chen
Summary: In this study, a deep learning algorithm was used to achieve rapid classification and diagnosis of coronary artery disease from CCTA images. The deep learning model can automatically segment the coronary artery quickly and accurately, delivering a diagnosis of >= 50% coronary artery stenosis. Artificial intelligence methods such as deep learning have the potential to significantly improve efficiency in CCTA image analysis.
EUROPEAN RADIOLOGY
(2022)
Article
Urology & Nephrology
Chan-Jung Liu, Wen-Huang Li, Chung-Hao Li, Jin-Shang Wu, Ze-Hong Lu, Yau-Sheng Tsai, Ting-Hsing Chao, Ho-Shiang Huang
Summary: Nephrolithiasis is significantly associated with coronary artery calcification, but not coronary luminal stenosis. However, the relationship between stone disease and CAD remains controversial, and further studies are needed to validate these findings.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jana Taron, Borek Foldyna, Thomas Mayrhofer, Michael T. Osborne, Nandini Meyersohn, Daniel O. Bittner, Stefan B. Puchner, Hamed Emami, Michael T. Lu, Maros Ferencik, Neha J. Pagidipati, Pamela S. Douglas, Udo Hoffmann
Summary: This study developed a risk prediction model for patients with nonobstructive CAD and found that advanced coronary plaque features have incremental value in discriminating clinical events in low-risk stable chest pain patients. ASCVD risk, degree of stenosis, and presence of HRP features independently predicted composite events in patients with nonobstructive CAD, improving model fit significantly. Patients with ASCVD >= 7.5%, any HRP, and mild/moderate stenosis had significantly higher rates of events compared to those who did not meet those criteria.
JACC-CARDIOVASCULAR IMAGING
(2021)
Article
Clinical Neurology
Wu Qiu, Hulin Kuang, Johanna Ospel, Michael D. Hill, Andrew Demchuk, Mayank Goyal, Bijoy Menon
Summary: A machine learning-based mCTA model can accurately predict brain tissue perfusion abnormality and follow-up infarction, comparable to CTP.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu Lan, Jin Shang, Yue Ma, Yanhua Zhen, Yuxue Dang, Dongqing Ren, Ting Liu, Ronghui Ju, Ning Guo, Ximing Wang, Yang Hou
Summary: This study evaluates the incremental predictive value of pericarotid fat density (PFD) on head and neck computed tomography angiography (CTA) for obstructive coronary artery disease (CAD) compared to a clinical risk model (Framingham risk score), carotid artery stenosis, and plaque type in acute ischemic stroke (AIS) or transient ischemic attack (TIA) patients without a known history of CAD. The results show that CTA-derived PFD measurements offer additional predictive value for obstructive CAD beyond the clinical risk model and stenosis, improving risk stratification for TIA or stroke patients without a history of CAD.
EUROPEAN RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Zengfa Huang, Beibei Cao, Xinyu Du, Mei Li, Jiong Huang, Zuoqin Li, Jianwei Xiao, Xiang Wang
Summary: We aimed to predict the risk of major adverse cardiovascular events (MACE) in patients with suspected non-obstructive coronary artery disease (CAD) by exploring classifications based on coronary computed tomography angiography (CTA). We compared these classifications with traditional non-obstructive CAD (NOCAD) classification, Duke prognostic NOCAD index, and Non-obstructive coronary artery disease reporting and data system (NOCAD-RADS). 4378 consecutive non-obstructive CAD patients were assessed, and the SPI classification, which focused on proximal involvement of plaques, provided important prognostic information for MACE prediction.
SCIENTIFIC REPORTS
(2023)
Review
Medicine, General & Internal
Dan L. Li, Marvin W. Kronenberg
Summary: Coronary artery disease is a major global health concern with noninvasive imaging tests playing a crucial role in its diagnosis and management. Myocardial perfusion imaging, along with other noninvasive tests such as stress echocardiography, coronary computed tomography angiography, and cardiac magnetic resonance imaging, have been widely used for evaluating ischemia and myocardial viability. The accuracy and clinical significance of these tests are essential in guiding risk stratification and revascularization decisions.
AMERICAN JOURNAL OF MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Georgios Benetos, Dominik C. Benz, Georgios P. Rampidis, Andreas A. Giannopoulos, Elia von Felten, Adam Bakula, Aleksandra Sustar, Tobias A. Fuchs, Aju P. Pazhenkottil, Catherine Gebhard, Philipp A. Kaufmann, Christoph Grani, Ronny R. Buechel
Summary: CAVi, derived from CCTA, is proposed as an indicator of diffuse atherosclerosis. This study found that CAVi is moderately correlated with stress MBF and MFR, and has incremental value in predicting abnormal stress MBF and ischemia compared to CCTA alone.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Martin Bodtker Mortensen, Sara Gaur, Attila Frimmer, Hans Erik Botker, Henrik Toft Sorensen, Kristian Hay Kragholm, Sand Ronnow Niels Peter, Flemming Hald Steffensen, Rebekka Vibjerg Jensen, Michael Maeng, Helle Kanstrup, Michael J. Blaha, Leslee J. Shaw, Omar Dzaye, Jonathon Leipsic, Bjarne Linde Norgaard, Jesper Moller Jensen
Summary: The diagnostic value of a 0 CAC score may vary with age, with smaller added diagnostic value for younger patients. In symptomatic patients under 60 years old, a significant proportion of obstructive CAD occurred in those without CAC and was associated with an increased risk of myocardial infarction and all-cause death.
Article
Radiology, Nuclear Medicine & Medical Imaging
Mahmoud Mohamed, Maria Bosserdt, Viktoria Wieske, Benjamin Dubourg, Hatem Alkadhi, Mario J. Garcia, Sebastian Leschka, Elke Zimmermann, Abbas A. Shabestari, Bjarne L. Norgaard, Matthijs F. L. Meijs, Kristian A. Ovrehus, Axel C. P. Diederichsen, Juhani Knuuti, Bjrn A. Halvorsen, Vladymir Mendoza-Rodriguez, Yung-Liang Wan, Nuno Bettencourt, Eugenio Martuscelli, Ronny R. Buechel, Hans Mickley, Kai Sun, Simone Muraglia, Philipp A. Kaufmann, Bernhard A. Herzog, Jean-Claude Tardif, Georg M. Schuetz, Michael Laule, David E. Newby, Stephan Achenbach, Matthew Budoff, Robert Haase, Federico Biavati, Aldo Vasquez Mezquita, Peter Schlattmann, Marc Dewey
Summary: Combining coronary computed tomography angiography (CCTA) with coronary artery calcium (CAC) score can significantly improve the diagnosis of coronary artery disease (CAD). The addition of CAC score is particularly beneficial when CCTA alone is inconclusive.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Rami M. M. Abazid, Jonathan G. G. Romsa, James C. C. Warrington, Cigdem Akincioglu, Osama A. A. Smettei, Yves Bureau, Nikolaos Tzemos, William C. C. Vezina
Summary: The study aimed to compare the prognostic value of coronary computed tomography angiography (CCTA) and single-photon emission computed tomography (SPECT) in predicting cardiovascular events. A retrospective analysis of 119 patients post-PCI who underwent hybrid imaging with CTA and SPECT was conducted. The results showed that CCTA could predict major adverse cardiovascular events, while SPECT could only predict cardiovascular events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Cheong-Il Shin, Sang Joon Park, Ji-Hyun Kim, Yeonyee Elizabeth Yoon, Eun-Ah Park, Bon-Kwon Koo, Whal Lee
Summary: The study found that SATM underestimated lumen parameters for computed lumen segmentation in CCTA, while this issue may be overcome by using the LATM method.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaofang Ban, Zhaoyue Li, Yuchen Duan, Ke Xu, Jie Xiong, Yingfeng Tu
Summary: This article reviews advanced techniques for coronary artery calcification imaging and their potential applications in both experimental and clinical settings, which provide the ability for early and accurate assessment of calcium content in atherosclerotic plaques.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qi Han, Feihua Jing, Zhiguo Sun, Fei Liu, Jucai Zhang, Jian Wang, Hongqin Liang
Summary: This study compared the diagnostic performance of a commercial coronary computed tomographic angiography artificial intelligence (CCTA-AI) platform with that of a reader, and found that the CCTA-AI platform has a slightly better performance in diagnosing coronary artery stenosis compared to radiologists with moderate experience.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Soongu Kwak, Seung-Ah Lee, Jaehyun Lim, Seokhun Yang, Hong-Mi Choi, In-Chang Hwang, Sahmin Lee, Yeonyee Elizabeth Yoon, Jun-Bean Park, Hyung-Kwan Kim, Yong-Jin Kim, Jong-Min Song, Goo-Yeong Cho, Kyung-Hwan Kim, Duk-Hyun Kang, Dae-Hee Kim, Seung-Pyo Lee
Summary: This study identified five distinct phenogroups of patients with severe primary mitral regurgitation (MR) and different risk profiles. The findings suggest that this phenogrouping strategy may improve risk stratification and optimize interventions for severe MR.
Article
Cardiac & Cardiovascular Systems
You-Jung Choi, Hyung-Kwan Kim, In-Chang Hwang, Chan Soon Park, Tae-Min Rhee, Hyun-Jung Lee, Jun-Bean Park, Yeonyee Elizabeth Yoon, Seung-Pyo Lee, Goo-Yeong Cho, Yong-Jin Kim
Summary: The study aimed to investigate the association between low-normal left ventricular ejection fraction (LVEF) and adverse outcomes in hypertrophic cardiomyopathy (HCM), as well as evaluate the predictive power of LVEF in the conventional HCM sudden cardiac death (SCD)-risk model. The results showed that low-normal LVEF was an independent predictor of heart failure hospitalization and cardiovascular death in patients with HCM.
Article
Cardiac & Cardiovascular Systems
You-Jung Choi, Darae Kim, Tea-Min Rhee, Hyun-Jung Lee, Jun-Bean Park, Seung-Pyo Lee, Sung-A Chang, Yong-Jin Kim, Eun-Seok Jeon, Jae K. Oh, Jin-Oh Choi, Hyung-Kwan Kim
Summary: The study aimed to investigate whether left arterial reservoir strain (LASr) could predict new-onset atrial fibrillation (NOAF) in patients with light-chain-type cardiac amyloidosis (ALCA). The results showed that LASr was an independent predictor of NOAF in ALCA patients.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Jun-Bean Park, Je-Yeon Yun, Bongsung Kim, Tae-Min Rhee, Hyun-Jung Lee, Heesun Lee, In-Chang Hwang, Yeonyee E. Yoon, Hyo Eun Park, Seung-Pyo Lee, Su-Yeon Choi, Yong-Jin Kim, Goo-Yeong Cho, Kyungdo Han, Hyung-Kwan Kim
Summary: This study found that patients with hypertrophic cardiomyopathy (HCM) have a higher risk of mental disorders compared to those without HCM. The risk is particularly high within the first year after HCM diagnosis, highlighting the importance of screening for mood and anxiety disorders in HCM patients.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hyue Mee Kim, In-Chang Hwang, Yeonyee Elizabeth Yoon, Jun-Bean Park, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim, Yaeji Lim, Goo-Yeong Cho
Summary: This study found that 2D global longitudinal strain (GLS) is associated with cardiovascular outcomes in patients with left bundle-branch block, but the predictive value of 3D speckle-tracking echocardiography has not been investigated in these patients. The study retrospectively analyzed the association between 2D and 3D strains and left ventricular ejection fraction (LVEF) in patients with preserved or reduced LVEF. The results showed that 2D-GLS is predictive of maintaining LVEF in patients with preserved LVEF, while a lower 3D-global circumferential strain is associated with persistently reduced LVEF in patients with reduced LVEF.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hack-Lyoung Kim
KOREAN CIRCULATION JOURNAL
(2023)
Article
Medicine, General & Internal
Jin Young Lee, Jean Kyung Bak, Mina Kim, Ho-Gyun Shin, Kyun-Ik Park, Seung-Pyo Lee, Hee-Sun Lee, Ju-Yeun Lee, Kwang-il Kim, Si-Hyuck Kang, Jang Hoon Lee, Se Yong Jang, Ju-Hee Lee, Kye Hun Kim, Jae Yeong Cho, Jae-Hyeong Park, Sue K. Park, Hae-Young Lee
Summary: This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. The results showed that the cardiovascular event rates were higher among patients with hypertension, even in low-risk populations. Systolic blood pressure levels >= 150 mmHg were significantly associated with the occurrence of cardiovascular events.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Soongu Kwak, Hyun-Jung Lee, Seungyeon Kim, Jun-Bean Park, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim
Summary: This study aimed to explore the differences in the association between cardiovascular risk factors and atherosclerotic cardiovascular disease (ASCVD) risk in men and women using machine learning. A random forest model was developed to predict the 10-year ASCVD probabilities in each sex. The results showed that there were significant sex-specific associations between cardiovascular risk factors and ASCVD events, with higher total cholesterol or LDL cholesterol levels being more strongly associated with the risk of ASCVD in men, while older age and increased waist circumference were more strongly associated with the risk of ASCVD in women.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Soongu Kwak, Seung-Ah Lee, Jaehyun Lim, Seokhun Yang, Doyeon Hwang, Hyun-Jung Lee, Hong-Mi Choi, In-Chang Hwang, Sahmin Lee, Yeonyee E. Yoon, Jun-Bean Park, Hyung-Kwan Kim, Yong-Jin Kim, Jong-Min Song, Goo-Yeong Cho, Duk-Hyun Kang, Dae-Hee Kim, Seung-Pyo Lee
Summary: In this study, a risk prediction model for post-mitral valve replacement mortality in severe degenerative mitral regurgitation patients was developed using machine learning. The model considered multiple risk factors such as age, hemoglobin, valve replacement, glomerular filtration rate, left atrial dimension, and left ventricular end-systolic diameter, and a simple scoring system was constructed for risk stratification.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Multidisciplinary Sciences
Sung-Hyuk Sunwoo, Myung-Jin Cha, Sang Ihn Han, Hyejeong Kang, Ye Seul Cho, Da-Hae Yeom, Chan Soon Park, Na Kyeong Park, Seong Woo Choi, Sung Joon Kim, Gi Doo Cha, Dongjun Jung, Suji Choi, Seil Oh, Gi-Byoung Nam, Taeghwan Hyeon, Dae-Hyeong Kim, Seung-Pyo Lee
Summary: The study proposed a method for treating ventricular tachyarrhythmia (VTA) using subthreshold electrical stimulations with a stretchable epicardial multi-channel electrode array. This method reduces pain, myocardial damage, and recurrence of arrhythmia, providing opportunities for painless ICD therapy.
Article
Cardiac & Cardiovascular Systems
You-Jung Choi, Hyun-Jung Lee, Ji-Suck Park, Chan Soon Park, Tae-Min Rhee, Jah Yeon Choi, Hong-Mi Choi, Jun-Bean Park, Yeonyee E. Yoon, Seung-Pyo Lee, Jin Oh Na, Goo-Yeong Cho, Yong-Jin Kim, In-Chang Hwang, Hyung-Kwan Kim
Summary: The aim of this study was to investigate the prognostic utility of left ventricular global longitudinal strain (LV-GLS) in patients with hypertrophic cardiomyopathy (HCM) and a left ventricular ejection fraction (LVEF) of 50-60%. The study included 349 HCM patients with an LVEF of 50-60%, and the results showed that LV-GLS was an independent predictor of a composite outcome including cardiovascular death in these patients. Therefore, LV-GLS can aid in risk stratification in HCM patients with an LVEF of 50-60%.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Biochemistry & Molecular Biology
Hack-Lyoung Kim, Hyun Sung Joh, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim
Summary: The study examined the associations of BMI and WC with ePWV. The results showed a stronger correlation between WC and ePWV, highlighting the significance of abdominal obesity in assessing cardiovascular risk.
Review
Peripheral Vascular Disease
Hack-Lyoung Kim, Sang Min Park, In Jeong Cho, Yu-Mi Kim, Dae-Hee Kim, Sung Hye Kim, Kwang-Il Kim, Ki-Chul Sung, Sang-Hyun Ihm, Jinho Shin, Yoonjung Kim, Kyungwon Oh, Eun Mi Lee
Summary: This article describes the blood pressure measurement protocol and quality control program in the Korea National Health and Nutrition Examination Survey (KNHANES). KNHANES transitioned to mercury-free auscultatory devices for blood pressure measurement in 2020 and will adopt Microlife as the unified device from 2023. Under the new protocol, blood pressure measurements are conducted three times with specific conditions, and the average of the second and third readings is used as the representative value. The quality control program ensures the competence of examiners and involves weekly calibration and on-site evaluations.
CLINICAL HYPERTENSION
(2023)
Review
Peripheral Vascular Disease
Hack-Lyoung Kim
Summary: Arterial stiffness and hypertension are closely related in pathophysiology and can lead to arterial wall damage and cardiovascular events. Early detection and treatment of arterial stiffness aid in preventing progression of vascular damage.
CLINICAL HYPERTENSION
(2023)