Article
Economics
Aino Vesikansa, Olli Halminen, Juha Mehtala, Iiris Horhammer, Teija Mikkola, Tero Ylisaukko-Oja, Miika Linna
Summary: Early start of anti-dementia medication is associated with lower healthcare and social care costs for Alzheimer's disease patients.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Clinical Neurology
Amir Abbas Tahami Monfared, Weicheng Ye, Aditya Sardesai, Henri Folse, Ameya Chavan, Elena Aruffo, Quanwu Zhang
Summary: This study used an evidence-based patient-level disease simulation model to estimate the long-term health outcomes of Lecanemab plus standard of care compared to standard of care alone in patients with early Alzheimer's disease. The findings showed that Lecanemab treatment can slow down disease progression, prolong the time spent in the early stages of the disease, and significantly improve patients' health outcomes.
NEUROLOGY AND THERAPY
(2023)
Article
Clinical Neurology
Amir Abbas Tahami Monfared, Ali Tafazzoli, Weicheng Ye, Ameya Chavan, Quanwu Zhang
Summary: This study used a disease simulation model to predict the long-term clinical outcomes of Lecanemab for patients with early AD. The results demonstrate that Lecanemab can slow disease progression, extend the duration of mild AD dementia, and reduce the lifetime probability of institutional care. Additionally, Lecanemab is associated with incremental life years and quality-adjusted life years, and a decrease in caregiver QALYs lost.
NEUROLOGY AND THERAPY
(2022)
Article
Cardiac & Cardiovascular Systems
Sarah Crook, Kacie Dragan, Joyce L. Woo, Matthew Neidell, Pengfei Jiang, Stephen Cook, Edward L. Hannan, Jane W. Newburger, Marshall L. Jacobs, Emile A. Bacha, Christopher J. Petit, Robert Vincent, Kathleen Walsh-Spoonhower, Ralph Mosca, T. K. Susheel Kumar, Neil Devejian, Steven A. Kamenir, George M. Alfieris, Michael F. Swartz, David Meyer, Erin A. Paul, John Billings, Brett R. Anderson
Summary: This study describes and identifies predictors of health care expenditures and utilization for Medicaid-insured pediatric cardiac surgical patients in New York State. The health care expenditures and utilization for cardiac surgical patients were significantly higher compared to non-cardiac surgical patients. Hispanic children had higher emergency department visits, inpatient admissions, and subspecialist visits, but fewer primary care visits and higher 5-year mortality.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Clinical Neurology
Norma B. Coe, Lindsay White, Melissa Oney, Anirban Basu, Eric B. Larson
Summary: This study estimated the spending attributable to Alzheimer's disease and related dementias (ADRD) by the United States government in the first 5 years post-diagnosis. The results revealed that the costs for traditional Medicare and Medicaid per dementia case over the first 5 years after diagnosis are $15,632 and $8,833 respectively. The majority of Medicare costs occur within the first 2 years, while Medicaid costs are concentrated among longer-lived beneficiaries who require long-term care.
ALZHEIMERS & DEMENTIA
(2023)
Article
Clinical Neurology
Ingrid S. S. Van Maurik, Hana M. M. Broulikova, Arenda Mank, Els D. D. Bakker, Arno De Wilde, Femke H. H. Bouwman, Andrew W. W. Stephens, Bart N. M. Van Berckel, Philip Scheltens, Wiesje M. M. Van Dser Flier
Summary: This study aimed to investigate the impact of a more precise diagnosis through amyloid PET on institutionalization, mortality, and healthcare costs. Results showed that patients who underwent amyloid PET had a lower risk of institutionalization and mortality, as well as lower healthcare costs, compared to those who did not undergo PET.
ALZHEIMERS & DEMENTIA
(2023)
Article
Multidisciplinary Sciences
Kathryn L. Humphreys, Lucy S. King, Katherine L. Guyon-Harris, Margaret A. Sheridan, Katie A. McLaughlin, Anca Radulescu, Charles A. Nelson, Nathan A. Fox, Charles H. Zeanah
Summary: This study examined the long-term effects of foster care as an alternative to institutional care on cognitive abilities. The results showed that individuals who received high-quality foster care had significantly higher IQ scores compared to those who received care as usual. The findings suggest that early investment in family care can lead to sustained gains in cognitive abilities, and fostering caregiving relationships is an important mechanism for intervention.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Geriatrics & Gerontology
Jasmine L. Travers, Grace F. Wittenberg, David R. Gifford, Ann Reddy, Marguerite M. McLaughlin, Rosa R. Baier
Summary: Understanding the experiences of persons living with dementia is crucial for providing high-quality care. The study highlights the importance of focusing on resident preferences and the need for experiential education for families and staff. However, there are barriers to implementing person-centered care in long-term care settings.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Economics
Wei Sun, Anthony Webb
Summary: Long-term care is a significant financial risk for elderly Americans, but only a small percentage purchase insurance, relying instead on Medicaid. To reduce Medicaid spending, states introduced long-term care partnership programs, but these programs only have a modest impact on insurance coverage and the majority of benefits go to those who would have purchased non-partnership policies, resulting in potential costs exceeding savings.
Article
Critical Care Medicine
Zachary D. W. Dezman, Paul Thurman, Ian Stockwell
Summary: Intentional injury, both self-harm and interpersonal, incurs significant long-term costs, with the median per-person healthcare cost for intentional injury in Maryland Medicaid recipients being $183 over a two-year period. However, the costs are highly skewed, ranging from a minimum of $2.56 to a maximum of $332,394.20. The top 5% of patients accounted for 55% of the overall costs.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2022)
Article
Food Science & Technology
Yufeng Du, Lin Song, Xiufang Dong, Hongyan Li, Wancui Xie, Yuming Wang, Hongxia Che
Summary: This study investigated the protective effects of long-term krill oil consumption on early cognitive impairment and found that krill oil can alleviate mild cognitive impairment by regulating the gut microbiome-short-chain fatty acid-brain axis.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Health Care Sciences & Services
Andrew J. Potter, John R. Bowblis
Summary: The study found that the implementation of MLTSS did not have a significant impact on nursing home quality, occupancy, or the percentage of low-care residents in NHs.
HEALTH SERVICES RESEARCH
(2021)
Article
Geriatrics & Gerontology
Lee A. Lindquist, Amber P. Miller-Winder, Allison Schierer, Alaine Murawski, Lauren Opsasnick, Laura M. Curtis, Kwang-Youn Kim, Vanessa Ramirez-Zohfeld
Summary: This study aims to investigate the cognitive aspects that impact older adults' AIP-LTC planning. The results show that adequate inductive reasoning and working memory are critical to AIP-LTC decision-making, while verbal abilities, long-term memory, and processing speed do not have an impact.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Neurosciences
Olli Halminen, Aino Vesikansa, Juha Mehtala, Iiris Horhammer, Teija Mikkola, Lauri J. Virta, Tero Ylisaukko-oja, Miika Linna
Summary: This study found that early initiation of anti-dementia medication can reduce the risk of AD patients transitioning to 24-hour care, while being unmarried, having an informal caregiver, having an additional neurological disorder diagnosis, or hip fracture are associated with a higher risk of needing 24-hour care when living independently at home.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Psychology, Multidisciplinary
Patricia Lannen, Clara Bombach, Fabio Sticca, Heidi Simoni, Oskar G. Jenni
Summary: This study assesses a protocol designed to mitigate risks in a population-based cohort of vulnerable individuals. The findings suggest that harm can be managed with a rigorous ethics protocol, enabling the voices of survivors to be heard.
FRONTIERS IN PSYCHOLOGY
(2022)