Article
Cardiac & Cardiovascular Systems
Carlo Mannina, Zhezhen Jin, Kenji Matsumoto, Kazato Ito, Angelo Biviano, Mitchell S. V. Elkind, Tatjana Rundek, Shunichi Homma, Ralph L. Sacco, Marco R. Di Tullio
Summary: In a study on subclinical atrial fibrillation and risk of ischemic stroke, it was found that elderly individuals have a higher frequency of other arrhythmias, with men and hypertensive patients more prone to certain arrhythmias, and differences in arrhythmia frequencies among ethnic groups such as whites, Blacks, and Hispanics.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Clinical Neurology
Francisco Purroy, Mikel Vicente-Pascual, Gloria Arque, Robert Begue, Joan Farre, Yhovany Gallego, Maria Pilar Gil-Villar, Gerard Mauri, Nuria Montala, Cristina Pereira, Coral Torres-Querol, Daniel Vazquez-Justes
Summary: The risk of NDAF after TIA is clinically significant, with factors such as female sex, age, previous ischemic heart disease, and cortical DWI pattern being associated with NDAF. NT-proBNP levels are related to the risk of NDAF within the first 5 years of follow-up. Patients with NDAF after admission and within 5 years have the highest risk of SIS.
FRONTIERS IN NEUROLOGY
(2022)
Article
Medicine, General & Internal
Benjamin Yong-Qiang Tan, Jamie Sin Ying Ho, Andrew Fu-Wah Ho, Pin Pin Pek, Aloysius Sheng-Ting Leow, Yogeswari Raju, Ching-Hui Sia, Leonard Leong-Litt Yeo, Vijay Kumar Sharma, Marcus Eng-Hock Ong, Joel Aik, Huili Zheng
Summary: Acute ischemic strokes (AIS) are closely associated with air pollution, and atrial fibrillation (AF) exacerbates the risk of AIS as ozone (O-3) and carbon monoxide (CO) concentrations increase, but reduces the risk with sulfur dioxide (SO2) concentration increase.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Stefan van Duijvenboden, Julia Ramirez, Michele Orini, Nay Aung, Steffen E. Petersen, Aiden Doherty, Andrew Tinker, Patricia B. Munroe, Pier D. Lambiase
Summary: This study found that exercise-induced premature ventricular contractions (PVCs) are closely associated with major adverse cardiovascular events, all-cause mortality, and heart failure in asymptomatic individuals. The risk increases as the PVC burden increases, and complex PVC rhythms pose a higher risk compared to PVC count alone. The study also suggests the presence of subclinical cardiomyopathy.
Article
Cardiac & Cardiovascular Systems
Po-Tseng Lee, Mu-Hsian Huang, Ting-Chung Huang, Chi-Hui Hsu, Sheng-Hsian Lin, Ping-Yen Liu
Summary: A large retrospective cohort study found that the burden of premature ventricular complex (PVC) is associated with new-onset atrial fibrillation (AF), and patients with higher PVC burden are at a higher risk of developing AF.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Multidisciplinary Sciences
Taylor Aurelius, Gie Ken-Dror, Sapna D. Sharma, Sageet Amlani, Gunaratnam Gunathilagan, David L. Cohen, Chakravarthi Rajkumar, Stuart Maguire, Sissi Ispoglou, Ibrahim Balogun, Anthea Parry, Lakshmanan Sekaran, Hafiz Syed, Enas Lawrence, Ravneeta Singh, Ahamad Hassan, Chris Wharton, Khalid Javaid, Neetish Goorah, Peter Carr, Eman Abdus Sami, Pankaj Sharma
Summary: South Asian stroke patients have a lower prevalence of atrial fibrillation compared to white British patients, but are more likely to be on antiplatelet treatment.
Article
Cardiac & Cardiovascular Systems
Hooman Kamel, Mary Farrant, J. Donald Easton, Luciano A. Sposato, Jordan J. Elm, Ellen Underwood, S. Claiborne Johnston
Summary: Among patients with cerebral ischemia, the distinction between TIA and minor stroke did not stratify the risk of subsequent AF diagnosis, implying that patients with TIA should undergo similar heart-rhythm monitoring strategies as patients with ischemic stroke.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Engineering, Biomedical
Syed Khairul Bashar, Dong Han, Fearass Zieneddin, Eric Ding, Timothy P. Fitzgibbons, Allan J. Walkey, David D. McManus, Bahram Javidi, Ki H. Chon
Summary: This paper proposes a novel density Poincare plot-based machine learning method for detecting AF from PAC/PVCs with high accuracy. By generating density Poincare plot, extracting features, and using classification algorithms, the method achieved superior performance in segment-wise cross-validation and validation on other databases.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Cardiac & Cardiovascular Systems
Yabing Duan, Haitao Xu, Baotong Li, Xin Yuan, Hansong Sun
Summary: This study evaluated the impact of different surgical methods for left atrial appendage treatment on long-term ischemic cerebrovascular events, and found that left atrial appendage excision can reduce the occurrence of stroke in patients with atrial fibrillation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Review
Cardiac & Cardiovascular Systems
Yirao Tao, Jing Xu, Xin Gong, Jingyi Sun, Donghui Yang
Summary: This study found that premature atrial complexes (PACs) are highly associated with atrial fibrillation occurrence in ischemic stroke patients, with frequent PACs potentially predicting future AF development. The presence of PACs in AF patients was correlated with stroke, and frequent PACs were identified as risk factors for asymptomatic AF and future AF occurrence in stroke patients. The definition of frequent PACs varied, with the cutoff being >70 beats/24 h based on Holter monitoring.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Clinical Neurology
Luciano A. Sposato, Seemant Chaturvedi, Cheng-Yang Hsieh, Carlos A. Morillo, Hooman Kamel
Summary: Atrial fibrillation detected after stroke or transient ischemic attack (AFDAS) may be a distinct clinical entity with lower cardiovascular comorbidity risk and less severe cardiac abnormalities compared to known atrial fibrillation. AFDAS is more frequently associated with insular brain infarction and has a lower associated risk of stroke.
Article
Medicine, General & Internal
Phan Dinh Phong, Bui Nguyen Tung, Pham Manh Hung, Nguyen Ngoc Quang, Nguyen Thi Thu Hoai, Nguyen Viet Dung, Thanh N. Nguyen, Dao Viet Phuong, Mai Duy Ton
Summary: This study found a high prevalence of atrial fibrillation (AF) in patients with transient ischemic attack (TIA) or ischemic stroke in Northern Vietnam, exceeding rates in other Southeast Asian countries. Age, renal dysfunction, valvular heart disease, and low ejection fraction were significantly associated with AF.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Jian Chen, Ying Zhao, Changsheng Ma, Xin Du, Yihua He, Hong Li
Summary: Left atrial (LA) remodeling is closely associated with cerebral stroke. However, the relationship between early-stage impaired deformability of the left atrium and stroke/transient ischemic attack (TIA) remains unclear. This study used speckle tracking echocardiography to evaluate changes in LA deformability and found that LA strain rate during left ventricular early diastole (SRE) was lower in the stroke/TIA group compared to the non-stroke/TIA group. Multiple regression analysis showed that SRE had a linear dependence on E/A ratio, LA volume index (VI), and body mass index, and SRE and sex ratio were independent risk factors for stroke/TIA.
Review
Clinical Neurology
Amit K. Kishore, Mohammad J. Hossain, Alan Cameron, Jesse Dawson, Andy Vail, Craig J. Smith
Summary: The performance of risk scores for predicting NDAF after ischemic stroke/transient ischemic attack varies widely, with uncertainty about their utility in clinical practice. Further studies using larger cohorts and randomized control trials are needed to evaluate the usefulness of these scores for clinical decision making and preventative intervention.
INTERNATIONAL JOURNAL OF STROKE
(2022)
Review
Biochemistry & Molecular Biology
Andrei Alexandru Mircea, Mihaela Rusu, Elisa Anamaria Liehn, Octavian Bucur
Summary: This review focuses on newly developed strategies, such as vernakalant and stereotactic ablative therapy, for the treatment of arrhythmias. These therapies are important for improving the management of atrial fibrillation and ventricular tachycardia, offering higher success rates and lower costs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Limeng Zhao, Hongmiao Tian, Haoran Liu, Weitian Zhang, Fabo Zhao, Xiaowen Song, Jinyou Shao
Summary: Artificial muscles are important for robotic applications. While rigid muscles have strong load-bearing capacity, their deformation is small, while soft muscles can deform extensively but have weak load-bearing capacity. Additionally, artificial muscles are usually controlled in an open loop without deformation-related feedback. Inspired by the coordination of muscles, bones, and nerves in human arms, a soft-rigid hybrid smart artificial muscle (SRH-SAM) is proposed. This SRH-SAM utilizes liquid crystal elastomer (LCE) for reversible deformation and helical metal wire for high bearing capacity and electric heating. It opens new possibilities for designing smart artificial muscles and promoting the development of muscle-based devices.
Article
Acoustics
Hui Wang, Xin-wu Yang, Fei Chen, Yuan-yuan Qin, Xuan-bo Li, Su-mei Ma, Jun-qiang Lei, Cai-ling Nan, Wei -yang Zhang, Wei Chen, Shun-lin Guo
Summary: The aim of this study was to develop a non-invasive tool based on radiomics and ultrasound features to evaluate axillary lymph node metastasis in patients with early invasive breast cancer. A total of 179 ABVS images were retrospectively analyzed and used to establish a radiomics nomogram model, which showed moderate predictive performance. This model can help clinicians choose diagnostic and therapeutic protocols for axillary lymph node metastasis.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
Article
Engineering, Environmental
Liping Xiao, Zhemeng Wang, Dongxue Wang, Yunlong Lan, Qiaoping Kong
Summary: A calcined CaMgAl-layered double hydroxide nanocomposite, CaMgAl-LDH (CCMA-0.83-600), was synthesized and employed for the removal of phosphate from wastewater. The adsorption process of phosphate by CCMA-0.83-600 was studied in detail, including the effects of initial pH, adsorbent dosage, and co-existing anions. The results suggested that CCMA-0.83-600 showed promising adsorption performance for phosphate removal with a pseudo-second-order kinetics and Langmuir isotherm behavior.
WATER SCIENCE AND TECHNOLOGY
(2023)
Review
Medicine, General & Internal
Ying-Jun Huo, Xiao-Ying Li, Meng Zhang, Chang Gao, Qian Xiao, Yu-Hong Zhao, Song Gao, Ting-Ting Gong, Qi-Jun Wu
Summary: This umbrella review comprehensively and quantitatively evaluated the associations between single nucleotide polymorphisms (SNPs) and ovarian cancer (OC) risk. The results revealed associations between SNPs and OC risk, with strong cumulative evidence for six SNPs (eight genetic models).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Jinglei Qu, Xin He, Ying Luo, Ping Yu, Ying Chen, Jing Liu, Xin Wang, Chang Wang, Tingting Liang, Yuxian Bai, Yu Han, Li Man, Chuanchun Leng, Caiyun Zhou, Lijie He, Yunpeng Liu, Xiujuan Qu
Summary: This study aimed to evaluate the efficacy and safety of second-line apatinib plus irinotecan for the treatment of advanced gastric adenocarcinoma and gastroesophageal junction adenocarcinoma. The results showed that apatinib plus irinotecan achieved a good treatment response and satisfactory survival with tolerable side effects.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Xiaoqiang Wang, Yi-ran Li, Yumiao Shi, Xiaoying Li, Jiamei Luo, Yiqi Zhang, Bo Qi, Feixiang Wu, Yuming Sun, Zhiying Pan, Jie Tian
Summary: This study aimed to explore the effects of dexmedetomidine on liver function and inflammation in patients with hepatocellular carcinoma after hepatectomy. The results showed that dexmedetomidine can effectively protect liver function, but has little effect on inflammation-related biomarkers.
FRONTIERS IN ONCOLOGY
(2023)
Review
Pharmacology & Pharmacy
Xintong Zhang, Yanhong Liu, Congcong Xiao, Youyan Guan, Zhonggao Gao, Wei Huang
Summary: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects approximately 1% of the global population. Gene therapy may hold potential as a treatment option for RA, as many existing therapeutic drugs have severe side effects. The use of nanoparticle delivery systems can improve the stability of nucleic acids and enhance transfection efficiency in vivo, thereby making gene therapy for RA safer and more effective. This review provides an overview of current nanomaterials and targeting ligands used in RA gene therapy, as well as various gene delivery systems that may inform future research.
Article
Radiology, Nuclear Medicine & Medical Imaging
Tong Pan, Yang Liu, Yang Yu, Dan Zhang, Yu-Han Sun, Hao-Wen Zhang, Cai-Ying Li
Summary: This study used 256-slice spiral CT to evaluate the role of morphological parameters of the right atrial appendage (RAA) and right atrium (RA) in the recurrence of atrial fibrillation (AF) after radiofrequency ablation (RFA). The results showed that an increase in diameter and volume of the RAA and RA, as well as tricuspid annulus diameter, may be correlated with AF recurrence. The short diameter of the RAA base had the highest predictive value for recurrence.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Agronomy
Weiyi Mu, Xiaoxian Duan, Quanjiu Wang, Xuesong Wei, Kai Wei, Yuanxin Li, Xin Guo
Summary: This study investigates the impact of irrigation amount (W), nitrogen (N), potassium (K), and zinc (Zn) on the net photosynthetic rate (Pn) of closely planted apple trees in an arid area. The results suggest that W, N, K, and Zn all significantly influence Pn, with W having the greatest relative importance. Additionally, the combination of W, N, and Zn is found to be the most effective, reducing W by 9.2% and 6.3% compared to other combinations.
Article
Chemistry, Physical
Yue-lun Wang, Xue-chun Zhang, Gui-gui Zhan, Mao-mao Wang, Wen-Qi Li, Jing-pei Cao
Summary: A comparison was made between hollow and mesoporous structures over ZSM-5 zeolites in methanol aromatization. Hollow zeolites with larger voids, more Bronsted acid sites and increased framework Al resulted in higher BTX selectivity. ZLC desorption of cyclohexane showed higher diffusion rate over mesoporous and hollow zeolites. However, lower Deff and higher activation energy of hollow zeolite indicated that surface barriers and pore blockage played a role in the limitation of mass transfer.
MOLECULAR CATALYSIS
(2023)
Correction
Biotechnology & Applied Microbiology
Xuyang Zhang, Minglu Xu, Qin Xue, Yao He
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Optics
Hao Li, Baolai Yang, Meng Wang, Chenhui Gao, Baiyi Wu, Lingfa Zeng, Xiaoming Xi, Zilun Chen, Xiaolin Wang, Zefeng Wang, Jinbao Chen
Summary: In this paper, a fs-laser phase mask inscription system based on a galvanometer scanning strategy is designed to fabricate large-core fiber Bragg gratings (FBGs). The performance of the fabricated FBGs is investigated using a high-power all-fiber oscillator, achieving a maximum output power of 7920 W and an optical-optical conversion efficiency of 77.3%. This work provides a flexible, stable, and economic scanning strategy for large-core FBG inscription and exhibits excellent performance for high-power fiber lasers.
Article
Food Science & Technology
Hao Hu, Mingming Qiu, Zhuzhu Qiu, Shipeng Li, Lintao Lan, Xingquan Liu
Summary: Wheat, as a globally distributed cereal, plays a vital role in the human diet. Long-term storage of wheat can lead to deterioration of its quality, reflected by changes in nutrient composition and starch structure. This study found that the quality of wheat significantly declined after two years of storage, with increased fatty acid content, malondialdehyde content, conductivity, and other indexes related to starch properties. SEM images showed damage on the surface of starch granules, while XRD analysis revealed a specific type of crystalline starch. FTIR spectra suggested a decrease in the amylose to amylopectin ratio, which affects wheat processing characteristics. To maintain reasonable quality, wheat should be stored at an average temperature of 20 degrees Celsius with safe water content for less than two years.
Article
Plant Sciences
Yang Li, Xiao Ma, Luo-Dan Xiao, Ya-Nan Yu, Hui-Ling Yan, Zhen-Hui Gong
Summary: The expression of CaWRKY50 is induced by Colletotrichum scovillei infection and salicylic acid (SA) treatments. CaWRKY50-silencing enhances pepper resistance to C. scovillei, while overexpression of CaWRKY50 increases susceptibility. CaWRKY50 suppresses the expression of two SA-related genes through binding to their promoters.
Article
Chemistry, Multidisciplinary
Guiqian Sun, Xingbin Zhao, Lu Chen, Yubo Fu, Wei Zhao, Meiyan Ye, Fei Wang, Qiang Tao, Shushan Dong, Pinwen Zhu
Summary: Nickel borides are promising materials with high hardness and excellent properties in catalysis and magnetism. The crystallization of Ni-B compounds with micro-size is still a challenge, and this study successfully synthesized single phases of various Ni-B compounds using high pressure and high temperature. The growth process of Ni-B compounds was found to involve Ni covering B to form Ni-B compounds. The findings of this work are significant for guiding the synthesis of highly crystalline transition metal borides in the future.
