The multi-faceted role of allergen exposure to the local airway mucosa

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

(2012) Marsha Wills-Karp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hematopoietic progenitor cells are innate Th2 cytokine-producing cells

(2011) Z. Allakhverdi et al.   ALLERGY

Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

(2011) H. Hammad et al.   ALLERGY

Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides

(2011) R. Vinhas et al.   ALLERGY

Persistent Activation of Dendritic Cells after Resolution of Allergic Airway Inflammation Breaks Tolerance to Inhaled Allergens in Mice

(2011) Leonie S. van Rijt et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of basophils in the pathogenesis of allergic disease

(2011) F. H. Falcone et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Purified Timothy grass pollen major allergen Phl p 1 may contribute to the modulation of allergic responses through a pleiotropic induction of cytokines and chemokines from airway epithelial cells

(2011) K. I. L. Röschmann et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Lung dendritic cell–epithelial cell crosstalk in Th2 responses to allergens

(2011) Monique Willart et al.   CURRENT OPINION IN IMMUNOLOGY

Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation

(2011) Jennifer Louten et al.   INTERNATIONAL IMMUNOLOGY

Defective epithelial barrier function in asthma

(2011) Chang Xiao et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

(2011) Chris J. Corrigan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation

(2011) Kentaro Takahashi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy

(2011) Sara J. Brown et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

One Remarkable Molecule: Filaggrin

(2011) Sara J. Brown et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mite allergen decreases DC-SIGN expression and modulates human dendritic cell differentiation and function in allergic asthma

(2011) H-J Huang et al.   Mucosal Immunology

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

Solution Structure of a Repeated Unit of the ABA-1 Nematode Polyprotein Allergen of Ascaris Reveals a Novel Fold and Two Discrete Lipid-Binding Sites

(2011) Nicola A. G. Meenan et al.   PLoS Neglected Tropical Diseases

Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation

(2010) W. Huvenne et al.   ALLERGY

Regulation of epithelial cell proliferation by bronchial fibroblasts obtained from mild asthmatic subjects

(2010) A. Semlali et al.   ALLERGY

Staphylococcus aureus invades the epithelium in nasal polyposis and induces IL-6 in nasal epithelial cells in vitro

(2010) F. Sachse et al.   ALLERGY

Allergen interactions with epithelium

(2010) Sanna Toppila-Salmi et al.   Current Opinion in Allergy and Clinical Immunology

Importance of disrupted intestinal barrier in inflammatory bowel diseases

(2010) Saʼad Y. Salim et al.   INFLAMMATORY BOWEL DISEASES

Common Filaggrin Null Alleles Are Not Associated with Hymenoptera Venom Allergy in Europeans

(2010) A. Aslam et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Increased IL-33 expression by epithelial cells in bronchial asthma

(2010) David Préfontaine et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins

(2010) Geoffrey A. Mueller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

Birch pollen allergen Bet v 1 binds to and is transported through conjunctival epithelium in allergic patients

(2009) J. Renkonen et al.   ALLERGY

Time-series nasal epithelial transcriptomics during natural pollen exposure in healthy subjects and allergic patients

(2009) P. Mattila et al.   ALLERGY

Dendritic Cell-Nerve Clusters Are Sites of T Cell Proliferation in Allergic Airway Inflammation

(2009) Tibor Z. Veres et al.   AMERICAN JOURNAL OF PATHOLOGY

Timothy grass pollen major allergen Phl p 1 activates respiratory epithelial cells by a non-protease mechanism

(2009) K. Röschmann et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Pattern recognition: recent insights from Dectin-1

(2009) Delyth M Reid et al.   CURRENT OPINION IN IMMUNOLOGY

Allergens are transported through the respiratory epithelium

(2009) Risto Renkonen et al.   Expert Review of Clinical Immunology

Par j 1 and Par j 2, the two major allergens in Parietaria judaica, bind preferentially to monoacylated negative lipids

(2009) Roberto González-Rioja et al.   FEBS Journal

Inflammation in Chronic Rhinosinusitis and Nasal Polyposis

(2009) Cornelis M. van Drunen et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Innate immune responses of airway epithelium to house dust mite are mediated through β-glucan–dependent pathways

(2009) Amy T. Nathan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Caveolar transport through nasal epithelium of birch pollen allergen Bet v 1 in allergic patients

(2009) Sakari Joenväärä et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations

(2009) Gaston De Serres et al.   JOURNAL OF CLINICAL VIROLOGY

IL-33 Induces IL-13-Dependent Cutaneous Fibrosis

(2009) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Human Epithelial Cells of the Respiratory Tract and the Skin Differentially Internalize Grass Pollen Allergens

(2009) Cornelia Blume et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Genetic Association Analysis of the Functional c.714T>G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease

(2009) Hilbert S. de Vries et al.   PLoS One

Modelling of Bet v 1 Binding to Lipids

(2009) K. Mattila et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway

(2008) A. B. Vroling et al.   ALLERGY

Cigarette smoke facilitates allergen penetration across respiratory epithelium

(2008) K. Gangl et al.   ALLERGY

Rhinovirus Disrupts the Barrier Function of Polarized Airway Epithelial Cells

(2008) Umadevi Sajjan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rhinovirus and the initiation of asthma

(2008) James E Gern   Current Opinion in Allergy and Clinical Immunology

Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis

(2008) Masanori Miyata et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+Foxp3+ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cells

(2008) A M Westendorf et al.   GUT

The role of respiratory viruses in cystic fibrosis

(2008) Dennis Wat et al.   Journal of Cystic Fibrosis

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

(2008) Aurelien Trompette et al.   NATURE

Protease Activity of Allergenic Pollen of Cedar, Cypress, Juniper, Birch and Ragweed

(2008) Hendra Gunawan et al.   ALLERGOLOGY INTERNATIONAL

Primary Nasal Epithelium Exposed to House Dust Mite Extract Shows Activated Expression in Allergic Individuals

(2007) Aram B. Vroling et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY