Anti-allergic action of anti-malarial drug artesunate in experimental mast cell-mediated anaphylactic models

Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma

(2012) Wanxing Eugene Ho et al.   FREE RADICAL BIOLOGY AND MEDICINE

GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1

(2012) Yasushi Ishijima et al.   GENES TO CELLS

Suppression of phospholipase Cγ1 phosphorylation by cinnamaldehyde inhibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells

(2011) Natsuko Kageyama-Yahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

(2011) Carrie A Morris et al.   MALARIA JOURNAL

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

(2011) Chang Cheng et al.   PLoS One

Tyrosine Kinase Syk Non-Enzymatic Inhibitors and Potential Anti-Allergic Drug-Like Compounds Discovered by Virtual and In Vitro Screening

(2011) Bruno O. Villoutreix et al.   PLoS One

Mast cell signaling: The role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants

(2010) Reuben P. Siraganian et al.   FEBS LETTERS

Anaphylaxis

(2010) F. Estelle R. Simons   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice

(2010) Ana Olivera et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-33 Is Produced by Mast Cells and Regulates IgE-Dependent Inflammation

(2010) Chia-Lin Hsu et al.   PLoS One

Pharmacokinetic Profiles of Artesunate After Single Intravenous Doses at 0.5, 1, 2, 4, and 8 mg/kg in Healthy Volunteers: A Phase I Study

(2009) Qigui Li et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Comparison of the anti-allergic activity of Syk inhibitors with optimized Syk siRNAs in FcεRI-activated RBL-2H3 basophilic cells

(2009) Michael P. Sanderson et al.   CELLULAR IMMUNOLOGY

Molecular mechanisms of endothelial hyperpermeability: implications in inflammation

(2009) Puneet Kumar et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell

(2009) Egle Passante et al.   INFLAMMATION RESEARCH

Mechanisms of mast cell signaling in anaphylaxis

(2009) Dean D. Metcalfe et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Analysis of the Mechanism for the Development of Allergic Skin Inflammation and the Application for Its Treatment: Mouse Models for the Development of Remedies for Human Allergic Dermatitis

(2009) Naoki Inagaki et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Advances in mast cell biology: new understanding of heterogeneity and function

(2009) T C Moon et al.   Mucosal Immunology

The Antiviral Activities of Artemisinin and Artesunate

(2008) Thomas Efferth et al.   CLINICAL INFECTIOUS DISEASES

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE

Artesunate for the Treatment of Severe Falciparum Malaria

(2008) Philip J. Rosenthal   NEW ENGLAND JOURNAL OF MEDICINE

Artemisinins: their growing importance in medicine

(2008) Sanjeev Krishna et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes

(2007) Ting-Ting Pan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY