Mutations inTERTpromoter andFGFR3and telomere length in bladder cancer

Distinguishing Nested Variants of Urothelial Carcinoma From Benign Mimickers by TERT Promoter Mutation

(2015) Minghao Zhong et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Genomic Profiling of Hepatocellular Adenomas Reveals Recurrent FRK-Activating Mutations and the Mechanisms of Malignant Transformation

(2014) Camilla Pilati et al.   CANCER CELL

BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer With Highest Recurrence

(2014) Mingzhao Xing et al.   JOURNAL OF CLINICAL ONCOLOGY

Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation withPtenloss in mice

(2014) Mona Foth et al.   JOURNAL OF PATHOLOGY

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer

(2014) Carl D. Morrison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma

(2014) Barbara Heidenreich et al.   Nature Communications

Mutational Context and Diverse Clonal Development in Early and Late Bladder Cancer

(2014) Iver Nordentoft et al.   Cell Reports

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

(2013) I. Kinde et al.   CANCER RESEARCH

TERT promoter mutations in cancer development

(2013) Barbara Heidenreich et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Telomerase Reverse Transcriptase Gene Promoter Mutations Help Discern the Origin of Urogenital Tumors: A Genomic and Molecular Study

(2013) Song Wu et al.   EUROPEAN UROLOGY

Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome

(2013) Yves Allory et al.   EUROPEAN UROLOGY

Comprehensive Mutation Analysis of the TERT Promoter in Bladder Cancer and Detection of Mutations in Voided Urine

(2013) Carolyn D. Hurst et al.   EUROPEAN UROLOGY

Prevalence and Co-Occurrence of Actionable Genomic Alterations in High-Grade Bladder Cancer

(2013) Gopa Iyer et al.   JOURNAL OF CLINICAL ONCOLOGY

Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

(2013) Guangwu Guo et al.   NATURE GENETICS

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy

(2013) Cristina Balbás-Martínez et al.   NATURE GENETICS

Overexpression and promoter mutation of the TERT gene in malignant pleural mesothelioma

(2013) A Tallet et al.   ONCOGENE

The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas

(2013) T Liu et al.   ONCOGENE

TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism

(2013) P. S. Rachakonda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

A Cell of Origin Gene Signature Indicates Human Bladder Cancer Has Distinct Cellular Progenitors

(2013) Garrett M. Dancik et al.   STEM CELLS

Telomerase: central regulator of all of the hallmarks of cancer

(2013) Kee Chung Low et al.   TRENDS IN BIOCHEMICAL SCIENCES

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

(2013) Jean Charles Nault et al.   Nature Communications

FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth

(2012) X. Du et al.   CANCER RESEARCH

Novel anticancer therapeutics targeting telomerase

(2012) Maria Ruden et al.   CANCER TREATMENT REVIEWS

Telomeres and Cancer: From Crisis to Stability to Crisis to Stability

(2012) Peter J. Campbell   CELL

Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases

(2012) Zhihu Ding et al.   CELL

Epidemiology and Risk Factors of Urothelial Bladder Cancer

(2012) Maximilian Burger et al.   EUROPEAN UROLOGY

Follow-up procedures for non-muscle-invasive bladder cancer: an update

(2012) Anastasios Anastasiadis et al.   Expert Review of Anticancer Therapy

Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer

(2012) Nuria Juanpere et al.   HUMAN PATHOLOGY

Human telomerase expression regulation

(2011) Marta Gladych et al.   Biochemistry and Cell Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of lung cancer

(2011) Min Shen et al.   LUNG CANCER

It all comes together at the ends: Telomerase structure, function, and biogenesis

(2011) Joshua D. Podlevsky et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Separation of telomerase functions by reverse genetics

(2011) S. Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bladder cancer: translating molecular genetic insights into clinical practice

(2010) Liang Cheng et al.   HUMAN PATHOLOGY

Telomere length measurement by a novel monochrome multiplex quantitative PCR method

(2009) R. M. Cawthon   NUCLEIC ACIDS RESEARCH

Ets2 Maintains hTERT Gene Expression and Breast Cancer Cell Proliferation by Interacting with c-Myc

(2008) Dakang Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY