Article
Obstetrics & Gynecology
Laura A. Wijs, Dorota A. Doherty, Jeffrey A. Keelan, Blagica Penova-Veselinovic, Peter Burton, John L. Yovich, Graham L. Hall, Peter D. Sly, Patrick G. Holt, Roger J. Hart
Summary: Adolescents conceived with assisted reproductive technologies (ART) show no difference in asthma prevalence compared to those conceived without, but have slightly altered lung function, increased rates of allergic rhinoconjunctivitis, food allergies, and positive skin prick testing.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Pediatrics
Salvatore Fasola, Giuliana Ferrante, Giovanna Cilluffo, Velia Malizia, Pietro Alfano, Laura Montalbano, Giuseppina Cuttitta, Stefania La Grutta
Summary: Identifying comorbidities in children with asthma is crucial for disease management. This study investigated the frequency of allergy-related comorbidities in asthmatic children and adolescents, and identified associated risk factors. It was found that several personal and environmental factors were significantly associated with the presence of comorbidities, potentially worsening the disease burden.
Article
Allergy
Marta Vazquez-Ortiz, Claudia Gore, Cherry Alviani, Elizabeth Angier, Katharina Blumchen, Pasquale Comberiati, Bettina Duca, Audrey DunnGalvin, Teresa Garriga-Baraut, M. Hazel Gowland, Britt Egmose, Rebecca Knibb, Ekaterina Khaleva, Charlotte G. Mortz, Oliver Pfaar, Helena Pite, Marcia Podesta, Alexandra F. Santos, Silvia Sanchez-Garcia, Frans Timmermans, Graham Roberts
Summary: This article summarizes practical resources to support the implementation of guidelines for adolescents and young adults with asthma and allergies in clinical practice. The study found that the identified resources cover various topics and target different stakeholders such as healthcare professionals, adolescents and young adults, parents/caregivers, schools, workplaces, and communities. However, most of the resources are web-based and in English, with limited evidence basis.
Article
Respiratory System
Reratilwe Mphahlele, Maia Lesosky, Refiloe Masekela
Summary: This study investigated the prevalence, severity, and risk factors for asthma in adolescents in Durban, South Africa. The results showed a higher prevalence of asthma compared to the global average, and severe symptoms were often underdiagnosed. Severe asthma symptoms were associated with allergies, environmental factors, and lifestyle choices. Equitable access to affordable controller inhalers is needed to address the burden of asthma in this setting.
BMJ OPEN RESPIRATORY RESEARCH
(2023)
Article
Immunology
Wei-Hsuan Sung, Kuo-Wei Yeh, Jing-Long Huang, Kuan-Wen Su, Kuan-Fu Chen, Chin-Chieh Wu, Ming-Han Tsai, Man-Chin Hua, Sui-Ling Liao, Shen-Hao Lai, Chih-Yung Chiu
Summary: The dynamic changes in BMI Z-scores during infancy are associated with atopic diseases, with a decreasing trend increasing the risk of IgE sensitization at age 1 and subsequent development of rhinitis at age 4. Exclusive formula feeding for over 6 months is significantly associated with mite sensitization at age 1.5 and risks asthma development at age 4.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Environmental Sciences
Christoph Muysers, Fabrizio Messina, Thomas Keil, Stephanie Roll
Summary: The subscreen package successfully identified significant subgrouping factors like younger mothers in the low SES group being associated with higher risk of asthma in their children, and teenagers in the low SES group having increased risks. Additionally, factors such as (parental) smoking or lack of contact with farm animals were identified as strong risk factors for rhinitis. The subscreen tool allows for comprehensive overview of odds ratios and disease proportions per subgroup in exploring the association between SES and respiratory allergies in childhood and youth.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Review
Immunology
Bianca Sampaio Dotto Fiuza, Hellen Freitas Fonseca, Pedro Milet Meirelles, Cintia Rodrigues Marques, Thiago Magalhaes da Silva, Camila Alexandrina Figueiredo
Summary: Exposure to different organisms can induce epigenetic changes affecting immune responses, potentially increasing susceptibility to inflammatory diseases. These changes, related to allergic diseases, may differ based on genetic backgrounds and influence different asthma or allergy phenotypes.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Nutrition & Dietetics
Anna Debinska, Barbara Sozanska
Summary: The global prevalence of allergic diseases and asthma has significantly increased in the last few decades. Diet has been hypothesized to be an important immunomodulatory factor influencing susceptibility to these diseases. Fermented food, as a natural source of living microorganisms and bioactive compounds, has been shown to have health-promoting potentials and is considered a promising strategy to reduce the risk of immune-related diseases such as allergic diseases and asthma.
Review
Pediatrics
Erik Melen, Gerard H. Koppelman, Ana Maria Vicedo-Cabrera, Zorana Jovanovic Andersen, Supinda Bunyavanich
Summary: This review discusses the impact of allergic diseases on children and adolescents globally, specifically focusing on allergies to food and airborne allergens, and provides examples of prevalence trends in the context of increasing climate change concerns. The profound environmental changes, such as loss of biodiversity, air pollution, and climate change, have been affecting natural systems. The potential links between these changes and allergic diseases in children are explored, along with their clinical implications. The review also discusses the correlation between relevant exposures for allergic diseases and epigenetic changes like DNA methylation, proposing that epigenetics could be a promising tool for capturing exposures and hazards related to a changing environment. Furthermore, it suggests that epigenetics might also provide promising biomarkers and help in understanding the mechanisms of allergic disease initiation and progression.
LANCET CHILD & ADOLESCENT HEALTH
(2022)
Article
Multidisciplinary Sciences
Ahmad Almatroudi, Ayman M. Mousa, Divya Vinnakota, Adil Abalkhail, Ameen S. S. Alwashmi, Saleh A. Almatroodi, Fahad A. Alhumaydhi, Russell Kabir, Ilias Mahmud
Summary: This study investigated the prevalence and factors associated with respiratory allergies in the Qassim region of Saudi Arabia. The prevalence of respiratory allergies was 28.8%, with family history, gender, and nationality being significant factors. Most patients received treatment, but a small percentage required hospitalization or emergency nebulization.
Article
Pediatrics
Turki S. Alahmadi, Moustafa A. Hegazi, Hani Alsaedi, Hanaa Hamadallah, Ali F. Atwah, Abdulrahman A. Alghamdi, Haya M. Altherwi, Majd S. Alghamdi, Ebtihal M. Albeshri, Moud I. Alzanbaqi, Abubaker M. Bamakhish, Mohamed S. El-Baz
Summary: This study aimed to identify the prevalence and risk factors of asthma in children/adolescents in Rabigh, Saudi Arabia. A cross-sectional epidemiological survey was conducted using a validated questionnaire, and data on sociodemographic characteristics and asthma risk factors were collected. The results showed a significant increase in the prevalence rates of physician-diagnosed asthma, any wheezing, and wheezing in the last 12 months among children/adolescents in Rabigh. These findings can be useful for future preventive plans and measures, particularly in improving air quality and limiting the increase in asthma prevalence in similar industrial communities.
Article
Allergy
Ali H. Ziyab, John W. Holloway, Yaser M. Ali, Hongmei Zhang, Wilfried Karmaus
Summary: This study aimed to estimate the prevalence of eczema symptoms and severity among adolescents in Kuwait, and assess the frequency of eczema-related nocturnal sleep disturbance and its relation to antihistamine use. The results showed that the prevalence of current eczema was 10.2%, and 12.7% of participants experienced sleep disturbance due to eczema more than once a week. Factors associated with eczema prevalence included underweight body mass index, Cesarean section delivery, and parental history of eczema.
WORLD ALLERGY ORGANIZATION JOURNAL
(2023)
Review
Nutrition & Dietetics
Alexandru Cosmin Pantazi, Cristina Maria Mihai, Adriana Luminita Balasa, Tatiana Chisnoiu, Ancuta Lupu, Corina Elena Frecus, Larisia Mihai, Adina Ungureanu, Mustafa Ali Kassim Kassim, Antonio Andrusca, Maria Nicolae, Viviana Cuzic, Vasile Valeriu Lupu, Simona Claudia Cambrea
Summary: The intestinal microbiota is a diverse and complex microecosystem that stabilizes by the age of three and plays a crucial role in human health, particularly in early childhood. Dysbiosis has been linked to the development of allergic diseases, such as atopic dermatitis, asthma, and food allergies. Next-generation sequencing methods have improved our understanding of the relationship between dysbiosis and allergic diseases. This review paper aims to synthesize the current knowledge on the development of the intestinal microbiota, its long-term impact on health, and the connection between dysbiosis and allergic diseases, as well as interventions for prevention and treatment.
Article
Respiratory System
Bronwyn Brew, Alison Gibberd, Guy B. Marks, Natalie Strobel, Clare Wendy Allen, Louisa Jorm, Georgina Chambers, Sandra Eades, Bridgette McNamara
Summary: This study identified potentially preventable risk factors for hospitalised asthma in Australian Aboriginal children, with risk factors including hospitalisation for acute respiratory tract infection, area-level disadvantage, prematurity, and low birth weight. Improving care for pregnant Aboriginal women and Aboriginal infants with ARTI may help reduce the burden of asthma in the Indigenous population.
Article
Psychology, Multidisciplinary
Inmaculada Mendez, Cecilia Ruiz-Esteban, Gloria Soto, Lucia Granados Alos, Mercedes Matas-Castillo
Summary: The study identified different adaptation profiles among adolescents, including maladjusted, at-risk, and adjusted groups. Significant differences in interpersonal risk factors were found depending on the adaptation profile. The results provide valuable insights for school and mental health programs to prevent misbehaving or risky behaviors.
FRONTIERS IN PSYCHOLOGY
(2021)
