Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells
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Title
Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF CANCER
Volume 138, Issue 2, Pages 497-506
Publisher
Wiley
Online
2015-08-11
DOI
10.1002/ijc.29725
References
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Note: Only part of the references are listed.- Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma
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- Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy
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- Current clinical trials with polo-like kinase 1 inhibitors in solid tumors
- (2013) Hyungshin Yim ANTI-CANCER DRUGS
- Initial testing (stage 1) of the polo-like kinase inhibitor volasertib (BI 6727), by the Pediatric Preclinical Testing Program
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- Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation
- (2013) F Rapino et al. Cell Death & Disease
- Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death
- (2013) J M Eichhorn et al. Cell Death & Disease
- Ewing Sarcoma: Clinical State-of-the-Art
- (2012) Jenny Potratz et al. PEDIATRIC HEMATOLOGY AND ONCOLOGY
- Eribulin Mesylate
- (2011) S. Jain et al. CLINICAL CANCER RESEARCH
- Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway
- (2011) I. Naumann et al. CLINICAL CANCER RESEARCH
- Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
- (2011) Ingrid E. Wertz et al. NATURE
- Preclinical Evidence that Use of TRAIL in Ewing's Sarcoma and Osteosarcoma Therapy Inhibits Tumor Growth, Prevents Osteolysis, and Increases Animal Survival
- (2010) G. Picarda et al. CLINICAL CANCER RESEARCH
- Phosphorylation of Mcl-1 by CDK1–cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest
- (2010) Margaret E Harley et al. EMBO JOURNAL
- Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
- (2010) Klaus Strebhardt NATURE REVIEWS DRUG DISCOVERY
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- (2010) Simone Fulda et al. NATURE REVIEWS DRUG DISCOVERY
- Cyclin-Dependent Kinase 1-Mediated Bcl-xL/Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis
- (2009) D. T. Terrano et al. MOLECULAR AND CELLULAR BIOLOGY
- Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas
- (2009) K. Hu et al. MOLECULAR CANCER THERAPEUTICS
- Tumor resistance to apoptosis
- (2008) Simone Fulda INTERNATIONAL JOURNAL OF CANCER
- Apoptosis: controlled demolition at the cellular level
- (2007) Rebecca C. Taylor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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