Review
Nutrition & Dietetics
Jose M. Comeche, Ana Gutierrez-Hervas, Jose Tuells, Cesare Altavilla, Pablo Caballero
Summary: Predefined diets have shown partial efficacy in treating inflammatory bowel disease, although doubts exist regarding specific indicators. Further research is needed to evaluate the influence of predefined diets on IBD patients.
Review
Immunology
Susanna Esposito, Giulia Antoniol, Marialuisa Labate, Lucrezia Passadore, Patrizia Alvisi, Valeria Dacco, Chiara Ghizzi, Carla Colombo, Nicola Principi
Summary: The incidence of inflammatory bowel diseases (IBDs) is rising globally, leading to a higher risk of infections in children with dysfunctional immune systems. Vaccines are essential for preventing these infections, and should be administered according to specific immunization guidelines for IBD patients. Compliance with vaccination recommendations is generally low, highlighting the need for multidisciplinary educational programs to improve vaccination coverage and protect children with IBD from vaccine-preventable diseases.
Review
Biochemistry & Molecular Biology
Maria Jose Sanchez-Quintero, Cristina Rodriguez-Diaz, Francisco J. Rodriguez-Gonzalez, Alejandra Fernandez-Castaner, Eduardo Garcia-Fuentes, Carlos Lopez-Gomez
Summary: Mitochondria play a crucial role in maintaining cellular functions and are involved in various cellular processes. Dysfunction of mitochondria has been linked to complex disorders, including inflammatory bowel diseases (IBD). The impact of mitochondrial dysfunction on IBD, including its role in intestinal mucosa, immune cell populations, mucosal repair, microbiota-brain-gut axes, and the development of colitis-associated colorectal cancer, is discussed in this review.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Clinical Neurology
Xuan Wang, Jian Wan, Min Wang, Yujie Zhang, Kaichun Wu, Fang Yang
Summary: This study demonstrates an association between multiple sclerosis (MS) and inflammatory bowel disease (IBD), with patients with MS having a higher risk of developing IBD and patients with IBD having a higher risk of developing MS.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2022)
Review
Medicine, General & Internal
Zsuzsanna Domokos, Eszter Uhrin, Bence Szabo, Mark Laszlo Czumbel, Fanni Dembrovszky, Beata Keremi, Gabor Varga, Peter Hegyi, Peter Hermann, Orsolya Nemeth
Summary: This study investigates the specific relationship between inflammatory bowel disease (IBD) and periodontitis and finds that IBD patients have a higher chance of developing periodontitis, making them a higher risk population in dentistry.
FRONTIERS IN MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Vincent Joustra, Ishtu L. Hageman, Jack Satsangi, Alex Adams, Nicholas T. Ventham, Wouter J. de Jonge, Peter Henneman, Geert R. D'Haens, Andrew Y. F. Li Yim
Summary: This article systematically reviewed and meta-analyzed DNA methylation studies related to inflammatory bowel disease (IBD). The results showed differential methylation in peripheral blood and confirmed previous observations. The study highlights the need for methodological homogenization and provides a basis for future research on epigenetic biomarkers of IBD in peripheral blood leukocytes.
JOURNAL OF CROHNS & COLITIS
(2023)
Review
Medicine, General & Internal
Hao Wu, Meihua Xu, Hong Hao, Michael A. Hill, Canxia Xu, Zhenguo Liu
Summary: Patients with inflammatory bowel disease (IBD) exhibit significant endothelial dysfunction, increased arterial stiffness, and carotid intima-media thickness (cIMT). Thus, patients with IBD may benefit from aggressive risk stratification for cardiovascular diseases.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Andrea Ballesio, Andrea Zagaria, Flavia Baccini, Federica Micheli, Giovanni Di Nardo, Caterina Lombardo
Summary: This study found that patients with inflammatory bowel disease have poorer subjective sleep quality compared to controls, with even worse sleep quality in those with active IBD. However, there were no differences within IBD subtypes. These results highlight the importance of considering sleep quality as a relevant comorbidity in IBD.
SLEEP MEDICINE REVIEWS
(2021)
Review
Biochemistry & Molecular Biology
HyunTaek Jung, Jae Seok Kim, Keum Hwa Lee, Kalthoum Tizaoui, Salvatore Terrazzino, Sarah Cargnin, Lee Smith, Ai Koyanagi, Louis Jacob, Han Li, Sung Hwi Hong, Dong Keon Yon, Seung Won Lee, Min Seo Kim, Paul Wasuwanich, Wikrom Karnsakul, Jae Il Shin, Andreas Kronbichler
Summary: Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that mainly affects young people. Recent studies have shown that microRNAs (miRNAs) play an important role in the pathogenesis, diagnosis, and treatment of IBD.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Review
Gastroenterology & Hepatology
Daniele Piovani, Alessandro Armuzzi, Stefanos Bonovas
Summary: A study found that individuals with a history of depression/depressive symptoms may be more susceptible to developing inflammatory bowel diseases (IBDs). In 13 studies, depression was significantly associated with the incidence of Crohn's disease and ulcerative colitis.
INFLAMMATORY BOWEL DISEASES
(2023)
Review
Gastroenterology & Hepatology
Kate Gallagher, Alexandra Catesson, Julian L. Griffin, Elaine Holmes, Horace R. T. Williams
Summary: This review summarizes metabolomic research in inflammatory bowel diseases, highlighting consistent metabolic perturbations such as increased levels of branched chain amino acids and lipid classes. It also emphasizes the underlying themes of perturbed gut microbial metabolism and mammalian-microbial co-metabolism associated with disease status.
JOURNAL OF CROHNS & COLITIS
(2021)
Review
Biochemistry & Molecular Biology
Federica Ghelli, Marco Panizzolo, Giacomo Garzaro, Giulia Squillacioti, Valeria Bellisario, Nicoletta Colombi, Enrico Bergamaschi, Irina Guseva Canu, Roberto Bono
Summary: This systematic review compares baseline values of pro/anti-inflammatory biomarkers in Exhaled Breath Condensate (EBC) in healthy, non-smoking adults, aiming to summarize the concentrations reported in the literature. The adherence to guidelines is crucial due to differences in methodologies employed in the included articles concerning EBC sampling, storage, and analyses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Cardiac & Cardiovascular Systems
A. S. Giordani, A. Candelora, M. Fiacca, C. Cheng, B. Barberio, A. Baritussio, R. Marcolongo, S. Iliceto, E. Carturan, M. De Gaspari, S. Rizzo, C. Basso, G. Tarantini, E. V. Savarino, A. L. P. Caforio
Summary: This study retrospectively analyzed data and conducted a literature review on myocarditis associated with inflammatory bowel diseases (IBD). It found that myocarditis in association with IBD is more common in young males and generally has a benign clinical course, but a subset of patients may develop giant cell myocarditis and require immunosuppression.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Katarzyna Dziabowska-Grabias, Malgorzata Sztanke, Przemyslaw Zajac, Michal Celejewski, Katarzyna Kurek, Stanislaw Szkutnicki, Patryk Korga, Wlodzimierz Bulikowski, Krzysztof Sztanke
Summary: Inflammatory bowel diseases (IBD) are chronic, incurable diseases of the digestive tract with unclear etiology, resulting in significant impact on patients' quality of life. The incidence and prevalence of IBD are continuously increasing worldwide, becoming a significant public health burden. Current pharmaceutical management options often have side effects and may not provide sufficient disease control, leading to research on antioxidant and anti-inflammatory substances as potential treatment options.
Article
Nutrition & Dietetics
Olga Maria Nardone, Francesco Manfellotto, Caterina D'Onofrio, Alba Rocco, Giovanni Annona, Francesca Sasso, Pasquale De Luca, Nicola Imperatore, Anna Testa, Roberto de Sire, Elio Biffali, Fabiana Castiglione
Summary: This study investigated the prevalence of lactose intolerance and its correlation with genetic analysis and H-BT in IBD patients. The results showed no significant difference in lactose intolerance prevalence between IBD patients and controls, and a significant association between wild-type genotype and lactose intolerance.