NF-κB and stat3 transcription factor signatures differentiate HPV-positive and HPV-negative head and neck squamous cell carcinoma

Using theRPackagecrlmmfor Genotyping and Copy Number Estimation

(2015) Robert B. Scharpf et al.   Journal of Statistical Software

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Correcting Transcription Factor Gene Sets for Copy Number and Promoter Methylation Variations

(2014) Komal S. Rathi et al.   DRUG DEVELOPMENT RESEARCH

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(2014) Malabika Sen et al.   MOLECULAR MEDICINE

Novel Insight into Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2014) Daria A. Gaykalova et al.   PLoS One

Activation of the NOTCH Pathway in Head and Neck Cancer

(2013) W. Sun et al.   CANCER RESEARCH

Targeting transcription factors

(2013) Jennifer E. Yeh et al.   CURRENT OPINION IN ONCOLOGY

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

(2013) L K Nottingham et al.   ONCOGENE

Preferential Activation of the Hedgehog Pathway by Epigenetic Modulations in HPV Negative HNSCC Identified with Meta-Pathway Analysis

(2013) Elana J. Fertig et al.   PLoS One

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

(2013) Sina Haftchenary et al.   ACS Medicinal Chemistry Letters

Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive Biomarkers

(2013) V. W. Y. Lui et al.   Cancer Discovery

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

NF-κΒ inhibition is ineffective in blocking cytokine-induced IL-8 production but P38 and STAT1 inhibitors are effective

(2012) Quan Wang et al.   INFLAMMATION RESEARCH

Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and immortalization

(2012) Erik R. Vandermark et al.   VIROLOGY

First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy

(2012) Malabika Sen et al.   Cancer Discovery

Human papillomavirus in head and neck cancers

(2011) Amanda Psyrri et al.   ANTI-CANCER DRUGS

Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma Surveillance

(2011) A. L. Carvalho et al.   CLINICAL CANCER RESEARCH

High-risk human papillomavirus in nasopharyngeal carcinoma

(2011) Aatur D. Singhi et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

(2011) Anil K. Chaturvedi et al.   JOURNAL OF CLINICAL ONCOLOGY

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

Regulation of Heparin-Binding EGF-Like Growth Factor by miR-212 and Acquired Cetuximab-Resistance in Head and Neck Squamous Cell Carcinoma

(2010) Hiromitsu Hatakeyama et al.   PLoS One

The tspair package for finding top scoring pair classifiers in R

(2009) J. T. Leek   BIOINFORMATICS

E6 and E7 Gene Silencing and Transformed Phenotype of Human Papillomavirus 16-Positive Oropharyngeal Cancer Cells

(2009) T. Rampias et al.   JNCI-Journal of the National Cancer Institute

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

(2009) James A Bonner et al.   LANCET ONCOLOGY

Defining and targeting transcription factors in cancer

(2009) Aisling M Redmond et al.   GENOME BIOLOGY

Bortezomib-Induced Apoptosis with Limited Clinical Response Is Accompanied by Inhibition of Canonical but not Alternative Nuclear Factor- B Subunits in Head and Neck Cancer

(2008) C. Allen et al.   CLINICAL CANCER RESEARCH

A signal network involving coactivated NF-κB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas

(2008) Tin Lap Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status

(2008) Bin Yan et al.   GENOME BIOLOGY