Randomised clinical trial: the efficacy of a transient receptor potential vanilloid 1 antagonist AZD1386 in human oesophageal pain

The Esophageal Multimodal Pain Model: Normal Values and Degree of Sensitization in Healthy Young Male Volunteers

(2011) Anne L. Krarup et al.   DIGESTIVE DISEASES AND SCIENCES

Increased TRPV1 gene expression in esophageal mucosa of patients with non-erosive and erosive reflux disease

(2010) M. P. L. Guarino et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Analgesic Efficacy of Peripheral κ-Opioid Receptor Agonist CR665 Compared to Oxycodone in a Multi-modal, Multi-tissue Experimental Human Pain Model

(2009) Lars Arendt-Nielsen et al.   ANESTHESIOLOGY

Evoked Human Oesophageal Hyperalgesia: A Potential Tool for Analgesic Evaluation?

(2009) Anne Estrup Olesen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Assessing efficacy of non-opioid analgesics in experimental pain models in healthy volunteers: an updated review

(2009) Camilla Staahl et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

TRP Channels and Pain

(2009) Daniel Cortright et al.   CURRENT PHARMACEUTICAL DESIGN

Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus

(2009) Christina Brock et al.   EUROPEAN JOURNAL OF PAIN

An endoscopic method for thermal and chemical stimulation of the human oesophagus

(2009) s. s. olesen et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats

(2009) r. m. van den wijngaard et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats

(2009) S. Peles et al.   NEUROSCIENCE

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acid hypersensitivity in patients with eosinophilic oesophagitis

(2009) Anne Lund Krarup et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway

(2008) Martin J. Gunthorpe et al.   DRUG DISCOVERY TODAY

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

(2008) Narender R. Gavva et al.   PAIN