Phospholipase A2, Oxidative Stress, and Neurodegeneration in Binge Ethanol-Treated Organotypic Slice Cultures of Developing Rat Brain

Effect of repetitive daily ethanol intoxication on adult rat brain: Significant changes in phospholipase A2 enzyme levels in association with increased PARP-1 indicate neuroinflammatory pathway activation

(2012) Nuzhath F. Tajuddin et al.   ALCOHOL

Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates

(2012) Jae Won Chang et al.   CHEMISTRY & BIOLOGY

NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

(2012) Liya Qin et al.   Journal of Neuroinflammation

Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration

(2012) Liya Qin et al.   Journal of Neuroinflammation

Integrating Cytosolic Phospholipase A2 with Oxidative/Nitrosative Signaling Pathways in Neurons: A Novel Therapeutic Strategy for AD

(2012) Grace Y. Sun et al.   MOLECULAR NEUROBIOLOGY

The inflammatory footprints of alcohol-induced oxidative damage in neurovascular components

(2011) Saleena Alikunju et al.   BRAIN BEHAVIOR AND IMMUNITY

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

Alcohol-Induced Interactive Phosphorylation of Src and Toll-like Receptor Regulates the Secretion of Inflammatory Mediators by Human Astrocytes

(2010) Nicholas A. Floreani et al.   Journal of Neuroimmune Pharmacology

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

Linking Binge Alcohol-Induced Neurodamage to Brain Edema and Potential Aquaporin-4 Upregulation: Evidence in Rat Organotypic Brain Slice Cultures and In Vivo

(2009) Kumar Sripathirathan et al.   JOURNAL OF NEUROTRAUMA

Arachidonic acid-induced apoptosis of human neuroblastoma SK-N-SH cells is mediated through mitochondrial alteration elicited by ROS and Ca2+-evoked activation of p38α MAPK and JNK1

(2009) Ku-Chung Chen et al.   TOXICOLOGY

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Alcohol-related dementia: a 21st-century silent epidemic?

(2008) Susham Gupta et al.   BRITISH JOURNAL OF PSYCHIATRY

Group VI Phospholipases A2: Homeostatic Phospholipases with Significant Potential as Targets for Novel Therapeutics

(2008) W. Wilkins III et al.   CURRENT DRUG TARGETS

Neuroinflammation as a neurotoxic mechanism in alcoholism: Commentary on “Increased MCP-1 and microglia in various regions of human alcoholic brain”

(2008) Edith V. Sullivan et al.   EXPERIMENTAL NEUROLOGY

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

(2008) Liya Qin et al.   Journal of Neuroinflammation

Trauma-Induced Cell Swelling in Cultured Astrocytes

(2008) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Binge Ethanol-induced Neurodegeneration in Rat Organotypic Brain Slice Cultures: Effects of PLA2 Inhibitor Mepacrine and Docosahexaenoic Acid (DHA)

(2008) James Brown et al.   NEUROCHEMICAL RESEARCH

Arachidonic acid induces both Na+and Ca2+entry resulting in apoptosis

(2007) Kwang-Ming Fang et al.   JOURNAL OF NEUROCHEMISTRY

Nitration of soluble proteins in organotypic culture models of Parkinson's disease

(2007) Trine R. Larsen et al.   NEUROCHEMISTRY INTERNATIONAL