Review
Immunology
Hanan S. Al-Khalaifah
Summary: Leishmaniasis is a significant global health problem with a high number of new cases and a large population at risk. Understanding the determinants of Leishmania pathogenicity and its survival mechanisms is important for developing effective treatments and vaccines.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Zhenzhen Wang, Yiming Niu, Xuejiao Tian, Na Yu, Xiaoyu Yin, Zhen Xing, Yurong Li, Lei Dong, Chunming Wang
Summary: A coating material has been developed to regulate inflammation around implants, promoting bone-implant integration under osteoporosis, representing a new strategy for designing immunomodulatory biomaterials for tissue regeneration.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Plant Sciences
Yan Liu, Qi-Zhang Li, Liu-Ding-Ji Li, Xuan-Wei Zhou
Summary: The study revealed that the intracellular polysaccharides from O. sinensis have immunomodulatory effects on macrophages by regulating the mRNA expression of pro-inflammatory and anti-inflammatory cytokines, activating macrophages, and improving phagocytosis. This effect is mediated through MAPK and PI3K/Akt signaling pathways.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Immunology
Linus Frick, Linda Hinterland, Kathrin Renner, Marion Vogl, Nathalie Babl, Simon Heckscher, Anna Weigert, Susanne Weiss, Joachim Glaesner, Raffaela Berger, Peter J. Oefner, Katja Dettmer, Marina Kreutz, Valentin Schatz, Jonathan Jantsch
Summary: This study indicates that local tissue acidosis can impair the anti-leishmanic activity of macrophages by reducing NO production. Normalization of intracellular pH can restore the activity of macrophages even in an acidic microenvironment.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Cell Biology
Juliana Ines Weber, Armanda Viana Rodrigues, Ana Valerio-Bolas, Telmo Nunes, Manuela Carvalheiro, Wilson Antunes, Graca Alexandre-Pires, Isabel Pereira da Fonseca, Gabriela Santos-Gomes
Summary: Leishmaniasis is a parasitic disease transmitted through the bite of sand flies. Macrophages are the target cells of the parasite and play a crucial role in the immune response. This study explored the communication between the parasite and host and its potential for developing therapeutic tools.
Review
Microbiology
Dan Zilberstein
Summary: Leishmania parasites reside in phagolysosomes of macrophages where they sense the lysosome-specific environment for differentiation initiation. Protein kinase A plays a crucial role as the gatekeeper in this process.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Microbiology
Eleanor C. Saunders, Marijke F. Sernee, Julie E. Ralton, Malcolm J. McConville
Summary: Leishmania parasites can survive long-term in the mature phagolysosome compartment of host cells by switching to a slow growth state and activating a stringent metabolic response. The heterogeneous expression of this response in vivo reflects temporal and spatial differences in lesion tissues, including dormant stages.
CURRENT OPINION IN MICROBIOLOGY
(2021)
Article
Immunology
Xin Yang, Shiwei Zhou, Hong Li, Jiangwen An, Chengheng Li, Ruigang Zhou, Ling Teng, Yongjian Zhu, Suya Liao, Yuhui Yang, Huricha Chen, Yun Chen
Summary: The polysaccharides from Alpiniae oxyphyllae fructus increased the phagocytic activity of macrophages and promoted the secretion of immune response-related factors, enhancing the Th2 immune response through macrophage activation. The structural characterization of these polysaccharides revealed they were composed of glucose units and exhibited a molecular weight of 44.3 kDa.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Gyu Hwan Hyun, Da-Hye Jeong, Yoon Young Yang, In Ho Cho, Yu-Jin Ha, Xiaohui Xing, D. Wade Abbott, Yves S. Y. Hsieh, Yun Pyo Kang, Jong-Ho Cha, Soon-Sun Hong, Seul Ji Lee, You-Sun Kim, Sung Won Kwon
Summary: Current cancer immunotherapeutic strategies mainly focus on remodeling the tumor microenvironment (TME) to make it favorable for antitumor immunity. A galactan-enriched nanocomposite (Gal-NC) has been developed as a carbohydrate nanoadjuvant with a macrophage-targeting feature, which can effectively restore and enhance the weakened antitumor immunity. Gal-NC mediates Toll-like receptor 4 (TLR4) activation, inducing the repolarization of tumor-associated macrophages (TAMs) towards immunostimulatory/tumoricidal M1-like phenotypes, leading to increased intratumoral population of cytotoxic T cells and synergistically enhancing T-cell-mediated antitumor response.
Article
Immunology
Divanshu Shukla, Ashok Patidar, Uddipan Sarma, Prashant Chauhan, Surya Prakash Pandey, Himanshu Singh Chandel, Neelam Bodhale, Soumya Kanti Ghosh, Carlos Alberto Guzman, Thomas Ebensen, Ricardo Silvestre, Arup Sarkar, Bhaskar Saha, Surajit Bhattacharjee
Summary: TLRs on host cells recognize PAMPs on pathogens and trigger immune responses. Leishmania infection alters TLR interdependency, revealing a unique immune evasive mechanism. Targeting TLR interdependency can induce a host-protective immune response against intracellular pathogens.
Article
Chemistry, Medicinal
Thitikan Summat, Sutee Wangtueai, Sangguan You, Weerawan Rod-in, Woo Jung Park, Supatra Karnjanapratum, Phisit Seesuriyachan, Utoomporn Surayot, Elena Talero, Javier avila-Roman, Kazuo Umezawa
Summary: Crude polysaccharides extracted from white jellyfish showed good anti-inflammatory activity, especially JF3. JF3 was able to inhibit NF-kappa B and MAPK-related inflammatory pathways, and also had an impact on the expression of CD11b and CD40.
Article
Pharmacology & Pharmacy
Carlos F. M. Silva, Teresa Leao, Filipa Dias, Ana M. Tomas, Diana C. G. A. Pinto, Eduardo F. T. Oliveira, Ana Oliveira, Pedro A. Fernandes, Artur M. S. Silva
Summary: Leishmaniasis is a neglected disease mainly affecting people in developing countries, with approximately 350 million people at risk. The lack of vaccines and chemotherapy has led to an increase in the incidence of the disease. A computational study focusing on a specific enzyme of the parasite has identified potential inhibitors, indicating the promise of using these compounds for developing novel antileishmanial drugs.
Article
Cell Biology
Yasmin Luz, Amanda Reboucas, Carla Polyana O. S. Bernardes, Erik A. Rossi, Taise S. Machado, Bruno S. F. Souza, Claudia Ida Brodskyn, Patricia S. T. Veras, Washington L. C. dos Santos, Juliana P. B. de Menezes
Summary: This study aimed to investigate the effects of Leishmania infection on the migration of macrophages and dendritic cells in a 3D environment and shed light on the underlying mechanisms. The results showed that Leishmania infection inhibited 3D migration of macrophages, while enhancing 3D migration of dendritic cells, and these effects were associated with changes in tumor necrosis factor expression and cell adhesion.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Microbiology
Hamlet Acevedo Ospina, Marie-Michele Guay-Vincent, Albert Descoteaux
Summary: Leishmania parasites colonize host phagocytes by altering host cell metabolism and mitochondrial biogenesis, through the action of lipophosphoglycan and type I interferon receptor signaling. These changes create a metabolically adapted environment conducive to parasite replication.
Article
Multidisciplinary Sciences
Aretha Chan, Jose-Mauricio Ayala, Fernando Alvarez, Ciriaco Piccirillo, George Dong, David Langlais, Martin Olivier
Summary: This study analyzed the early innate inflammatory events during L. major infection, confirming the significant role of the virulence factor GP63 in providing favorable conditions for host cell infection. The data suggest that GP63 does not greatly influence pathogen-induced inflammatory cell recruitment, but rather affects their activation status and effector function, as well as potentially influencing the internalization of promastigotes during early infection.
Article
Biochemistry & Molecular Biology
Edson Hipolito Junior, Alan G. Goncalves, Miguel D. Noseda, Maria Eugenia R. Duarte, Fabio S. Murakami, Diogo R. B. Ducatti
Summary: This article discusses the semisynthesis of N-alkyl-kappa-carrageenan derivatives and their antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. It was found that derivatives with longer alkyl chains exhibited higher antibacterial activity.
CARBOHYDRATE RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Rafaela Aparecida Pereira, Amanda do Rocio Andrade Pires, Aurea Echevarria, Danilo Sousa-Pereira, Guilhermina Rodrigues Noleto, Silvia Maria Suter Correia Cadena
Summary: Mesoionic compounds MI-J and MI-D show significant antitumor effects on hepatocellular carcinoma cells, exhibiting stronger cytotoxicity in cells grown in galactose medium. Both compounds depress mitochondrial respiration and reduce ATP levels, leading to cytotoxicity in cancer cells.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Biology
Alexandre de Fatima Cobre, Dile Pontarolo Stremel, Guilhermina Rodrigues Noleto, Mariana Millan Fachi, Monica Surek, Astrid Wiens, Fernanda Stumpf Tonin, Roberto Pontarolo
Summary: This study implemented machine learning models to predict COVID-19 diagnosis and disease severity, showing that the models were able to classify negative and positive samples, as well as severe and non-severe disease, with key predictive factors including blood indicators and physiological measures.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Review
Biotechnology & Applied Microbiology
Guilherme Augusto Colusse, Jaqueline Carneiro, Maria Eugenia Rabello Duarte, Julio Cesar de Carvalho, Miguel Daniel Noseda
Summary: Microalgae are valuable resources for polysaccharide production, with great potential in various industries. Despite the importance of polysaccharides in different sectors, further research is needed on microalgal polysaccharide production, biological activity, and chemical structure. Future advancements hinge on addressing challenges in microalgal cultivation techniques and polysaccharide production to drive innovative technological developments.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ester Mazepa, Miguel D. Noseda, Luciana G. Ferreira, Mariana M. de Carvalho, Alan G. Goncalves, Diogo R. B. Ducatti, Daniel de L. Bellan, Rafaela P. Gomes, Edvaldo da S. Trindade, Celia R. C. Franco, Franciane M. Pellizzari, Sheila M. B. Winnischofer, Maria E. R. Duarte
Summary: A water-soluble sulfated heterorhamnan (Gb1) was isolated from the green seaweed Gayralia brasiliensis and its purified form (Gb1r) showed potent inhibitory effects on U87MG human glioblastoma cells. Gb1 and Gb1-OS had different effects on cell viability, with Gb1 causing cell cycle arrest and Gb1-OS inducing apoptosis. These differences in effects may be related to variations in sulfate content and position along the polysaccharide chains.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Plant Sciences
Roberta Paulert, Roberta Ascrizzi, Silvia Malatesta, Paolo Berni, Miguel Daniel Noseda, Mariana Mazetto de Carvalho, Ilaria Marchioni, Luisa Pistelli, Maria Eugenia Rabello Duarte, Lorenzo Mariotti, Laura Pistelli
Summary: This study investigated the eliciting effect of an aqueous extract from Ulva intestinalis, mainly composed of ulvan, on basil and parsley plants. The results showed an increase in salicylic acid in parsley and accumulation of jasmonic and abscisic acids in basil, indicating a priming effect. Additionally, the elicitation caused changes in essential oil chemotypes and accumulation of specific compounds, suggesting a defensive response to the extract.
Article
Biochemistry & Molecular Biology
Ingrid Fatima Zattoni, Thales Kronenberger, Diogo Henrique Kita, Lais Danciguer Guanaes, Matheus Murmel Guimaraes, Larissa de Oliveira Prado, Melanie Ziasch, Luis C. Vesga, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Marcos Brown Goncalves, Miguel D. Noseda, Diogo R. B. Ducatti, Antti Poso, Robert W. Robey, Suresh Ambudkar, Vivian Rotuno Moure, Alan Guilherme Goncalves, Glaucio Valdameri
Summary: A newly discovered porphyrin derivative (4B) was identified as an inhibitor of the ABCG2 transporter, capable of overcoming multidrug resistance in vitro and showing selective inhibition towards ABCG2 without being transported by it.
CHEMICO-BIOLOGICAL INTERACTIONS
(2022)
Article
Cell Biology
Marilia Locatelli Correa-Ferreira, Amanda do Rocio Andrade Pires, Igor Resendes Barbosa, Aurea Echevarria, Guilherme Henrique Pedrassoli, Sheila Maria Brochado Winnischofer, Guilhermina Rodrigues Noleto, Silvia Maria Suter Correia Cadena
Summary: This study evaluated the cytotoxic effect of MI-D on T98G glioblastoma cells and found that MI-D exerts cytotoxicity by impairing mitochondrial oxidative phosphorylation.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Paloma Kalegari, Daniela Morais Leme, Geonildo Rodrigo Disner, Marta Margarete Cestari, Daniel de Lima Bellan, Willian Vanderlei Meira, Ester Mazepa, Glaucia Regina Martinez
Summary: The presence of higher amounts of melanin in melanoma cells may affect the levels of DNA damage when subjected to RBAc-PDT treatment.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Gabriela Araujo Moreira, Andre Ivan Bradley dos Santos Dias, Silvia Maria Suter Correia Cadena, Marilia Locatelli Correa-Ferreira, Sergio Ossamu Ioshii, Camila Girardi Fachin
Summary: This study aimed to evaluate the effects of sildenafil and l-arginine in the prevention of necrotizing enterocolitis. The results showed that these drugs were not effective in reducing intestinal injury.
SCIENTIFIC REPORTS
(2022)
Review
Energy & Fuels
Michelle Dias Hornes da Rosa, Cristina Jansen Alves, Felipe Nardo dos Santos, Alexander Ossanes de Souza, Elessandra da Rosa Zavareze, Ernani Pinto, Miguel Daniel Noseda, Daniela Ramos, Claudio Martin Pereira de Pereira
Summary: This article provides a brief and critical review of algae production in the food and energy industries. It summarizes the reasons for interest in algae cultivation, including the valuable phytochemicals in the food market, bioenergetic potential, and uses of algal waste biomass. The study also highlights the emergence of algae biorefineries. It concludes that despite the need for further research, algae biorefineries offer solutions for the food, chemical, and energy markets.
Article
Cell Biology
Ester Mazepa, Ana Luiza Dorigan de Matos Furlanetto, Hulyana Brum, Lia Sumie Nakao, Pierina Alexandra Martinez, Silvia Maria Suter Correia Cadena, Maria Eliane Merlin Rocha, Elizabeth Sousa Cunha, Glaucia Regina Martinez
Summary: In this study, we found that the activity of secreted QSOX is higher in melanoma cells and is further increased after stimulation of melanogenesis. Depleting intracellular GSH disrupts the redox homeostasis and increases oxidative stress in the cells. These findings suggest that QSOX and GSH play important roles in melanogenesis and cellular adaptive response.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2023)
Article
Thermodynamics
Jaqueline Carneiro, Juliana C. C. Dallagnol, Andressa Veiga, Miguel D. Noseda, Maria Eugenia R. Duarte, Marco A. Carvalho Filho, Diogo R. B. Ducatti, Alan G. Goncalves, Fabio S. Murakami
Summary: The research investigated the thermal properties of porphyrins containing pyridyl, aminophenyl, and nitrophenyl groups, with tetrapyridylporphyrin being the most thermally stable and β-nitrotetraphenylporphyrin being the least stable upon heating. Thermal analysis showed different behaviors during heating for various porphyrins.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
