HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127

Differential Regulation of Human IL-7 Receptor   Expression by IL-7 and TCR Signaling

(2014) N. L. Alves et al.   JOURNAL OF IMMUNOLOGY

Cytokine production and dysregulation in HIV pathogenesis: Lessons for development of therapeutics and vaccines

(2012) Morgan A. Reuter et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The role of cytokines in the establishment, persistence and eradication of the HIV reservoir

(2012) Claire Vandergeeten et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The CD8+HLA-DR+T cells expanded in HIV-1 infection are qualitatively identical to those from healthy controls

(2012) Hiromi Imamichi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammation, Coagulation and Cardiovascular Disease in HIV-Infected Individuals

(2012) Daniel A. Duprez et al.   PLoS One

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

(2012) M. A. Paley et al.   SCIENCE

HIV infection perturbs interleukin-7 signaling at the step of STAT5 nuclear relocalization

(2011) Ivan Landires et al.   AIDS

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

(2011) A. R. Hersperger et al.   BLOOD

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

(2011) Margalida Rotger et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 and CD8 T Cell Immune Activation during Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7

(2011) M. Catalfamo et al.   JOURNAL OF IMMUNOLOGY

Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines

(2011) L. Flatz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

Early events governing memory CD8+ T-cell differentiation

(2010) J. J. Obar et al.   INTERNATIONAL IMMUNOLOGY

Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation

(2010) Kirsten M.L. Hertoghs et al.   JOURNAL OF CLINICAL INVESTIGATION

Soluble IL-7R  (sCD127) Inhibits IL-7 Activity and Is Increased in HIV Infection

(2010) A. M. Crawley et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche

(2010) A. Banerjee et al.   JOURNAL OF IMMUNOLOGY

IL-7-dependent STAT-5 activation and CD8+ T cell proliferation are impaired in HIV infection

(2010) A. Vranjkovic et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

Antiretroviral therapy initiation during primary HIV infection enhances both CD127 expression and the proliferative capacity of HIV-specific CD8+ T cells

(2009) Camille Lécuroux et al.   AIDS

Soluble IL-7Ralpha (sCD127) and Measurement of IL-7 in the Plasma of HIV Patients

(2009) Marie-Christine Blom-Potar et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory

(2009) P. Agarwal et al.   JOURNAL OF IMMUNOLOGY

Identification and Biochemical Characterization of Human Plasma Soluble IL-7R: Lower Concentrations in HIV-1-Infected Patients

(2009) T. Rose et al.   JOURNAL OF IMMUNOLOGY

Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

(2009) S. A. Migueles et al.   JOURNAL OF VIROLOGY

The cunning little vixen: Foxo and the cycle of life and death

(2009) Stephen M Hedrick   NATURE IMMUNOLOGY

Disruption of the γc cytokine network in T cells during HIV infection

(2008) Danylo Sirskyj et al.   CYTOKINE

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

CD8+ T-Cell Interleukin-7 Receptor Alpha Expression as a Potential Indicator of Disease Status in HIV-Infected Children

(2008) Tanvi S. Sharma et al.   PLoS One

HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells

(2008) M. Catalfamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

(2008) Lewis H Kuller et al.   PLOS MEDICINE

T-cell exhaustion in HIV infection

(2008) Mohamed El-Far et al.   Current HIV/AIDS Reports

Chronic innate immune activation as a cause of HIV-1 immunopathogenesis

(2007) Adriano Boasso et al.   CLINICAL IMMUNOLOGY