A novel bivalent HIV-1 entry inhibitor reveals fundamental differences in CCR5-μ-opioid receptor interactions between human astroglia and microglia

The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial

(2013) P. W. Hunt et al.   BLOOD

HIV and Recent Illicit Drug Use Interact to Affect Verbal Memory in Women

(2013) Vanessa J. Meyer et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

A bivalent ligand targeting the putative mu opioid receptor and chemokine receptor CCR5 heterodimer: binding affinity versus functional activities

(2013) Yunyun Yuan et al.   MedChemComm

Opiate Drug Use and the Pathophysiology of NeuroAIDS

(2012) Kurt F. Hauser et al.   CURRENT HIV RESEARCH

Association of Polymorphisms of the Mu Opioid Receptor Gene with the Severity of HIV Infection and Response to HIV Treatment

(2012) Dmitri Proudnikov et al.   JOURNAL OF INFECTIOUS DISEASES

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

(2012) Seth M. Dever et al.   JOURNAL OF NEUROVIROLOGY

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5

(2012) Yunyun Yuan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue

(2012) Maria P Gonzalez-Perez et al.   Retrovirology

Neurocognitive Impact of Substance Use in HIV Infection

(2011) Desiree A Byrd et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

CNS effects of a CCR5 inhibitor in HIV-infected subjects: a pharmacokinetic and cerebral metabolite study

(2011) L. Garvey et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Protein Kinase Cζ Mediates μ-Opioid Receptor-induced Cross-desensitization of Chemokine Receptor CCR5

(2011) Changcheng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Coinfection and Morphine Coexposure Severely Dysregulate Hepatitis C Virus-Induced Hepatic Proinflammatory Cytokine Release and Free Radical Production: Increased Pathogenesis Coincides with Uncoordinated Host Defenses

(2011) N. El-Hage et al.   JOURNAL OF VIROLOGY

Substance abuse increases the risk of neuropathy in an HIV-infected cohort

(2011) Jessica Robinson-Papp et al.   MUSCLE & NERVE

HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types

(2011) Gretja Schnell et al.   PLoS Pathogens

Methadone maintenance therapy promotes initiation of antiretroviral therapy among injection drug users

(2010) Sasha Uhlmann et al.   ADDICTION

Integrated Opioid Use Disorder and HIV Treatment: Rationale, Clinical Guidelines for Addiction Treatment, and Review of Interactions of Antiretroviral Agents and Opioid Agonist Therapies

(2010) Marcelo F. Batkis et al.   AIDS PATIENT CARE AND STDS

Human immunodeficiency virus-associated neurocognitive disorder

(2010) Avindra Nath   Annals of the New York Academy of Sciences

Synthesis and Evaluation of a Near-Infrared Fluorescent Non-Peptidic Bivalent Integrin αvβ3Antagonist for Cancer Imaging

(2010) Feng Li et al.   BIOCONJUGATE CHEMISTRY

Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers

(2010) Iain C. Anthony et al.   BRAIN

Bivalent β-Carbolines as Potential Multitarget Anti-Alzheimer Agents

(2010) Yvonne Rook et al.   JOURNAL OF MEDICINAL CHEMISTRY

Time to act: a call for comprehensive responses to HIV in people who use drugs

(2010) Chris Beyrer et al.   LANCET

A bivalent ligand (KMN-21) antagonist for μ/κ heterodimeric opioid receptors

(2009) Shijun Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of a bivalent μ opiate and adenosine A1 receptor antagonist

(2009) Smitha C. Mathew et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CCL5/RANTES Gene Deletion Attenuates Opioid-Induced Increases in Glial CCL2/MCP-1 Immunoreactivity and Activation in HIV-1 Tat-Exposed Mice

(2008) Nazira El-Hage et al.   Journal of Neuroimmune Pharmacology

Morphine Exacerbates HIV-1 Tat-Induced Cytokine Production in Astrocytes through Convergent Effects on [Ca2+]i, NF-κB Trafficking and Transcription

(2008) Nazira El-Hage et al.   PLoS One