Anti-HIV-1 antibodies 2F5 and 4E10 interact differently with lipids to bind their epitopes

Ablation of the Complementarity-Determining Region H3 Apex of the Anti-HIV-1 Broadly Neutralizing Antibody 2F5 Abrogates Neutralizing Capacity without Affecting Core Epitope Binding

(2010) J. P. Julien et al.   JOURNAL OF VIROLOGY

Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution

(2010) X. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

(2010) E. M. Scherer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

4E10 and 2F5 monoclonal antibodies: binding specificities to phospholipids, tolerance, and clinical safety issues

(2009) Carl R Alving   AIDS

Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid epitopes

(2009) Gary R Matyas et al.   AIDS

Accurate Determination of Membrane Dynamics with Line-Scan FCS

(2009) Jonas Ries et al.   BIOPHYSICAL JOURNAL

Interactions of HIV-1 Antibodies 2F5 and 4E10 with a gp41 Epitope Prebound to Host and Viral Membrane Model Systems

(2009) Ana S. Veiga et al.   CHEMBIOCHEM

Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity

(2009) H. Xu et al.   JOURNAL OF VIROLOGY

Stable Docking of Neutralizing Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Monoclonal Antibodies 2F5 and 4E10 Is Dependent on the Membrane Immersion Depth of Their Epitope Regions

(2009) S. M. Dennison et al.   JOURNAL OF VIROLOGY

A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

(2009) R. Pejchal et al.   JOURNAL OF VIROLOGY

Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface

(2009) L. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of HIV membrane in neutralization by two broadly neutralizing antibodies

(2009) S. M. Alam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission

(2008) Maier Lorizate et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Fluorescence correlation spectroscopy in membrane structure elucidation

(2008) Salvatore Chiantia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1

(2008) Gary R. Matyas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipid modulation of membrane-bound epitope recognition and blocking by HIV-1 neutralizing antibodies

(2008) Nerea Huarte et al.   FEBS LETTERS

HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane

(2008) Zhen-Yu J. Sun et al.   IMMUNITY

Membrane-specific antibodies induced by liposomes can simultaneously bind to HIV-1 protein, peptide, and membrane lipid epitopes

(2008) Zoltan Beck et al.   JOURNAL OF DRUG TARGETING

Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site

(2008) Jean-Philippe Julien et al.   JOURNAL OF MOLECULAR BIOLOGY

The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 4E10 Monoclonal Antibody Is Better Adapted to Membrane-Bound Epitope Recognition and Blocking than 2F5

(2008) N. Huarte et al.   JOURNAL OF VIROLOGY

The Membrane-Proximal External Region of the Human Immunodeficiency Virus Type 1 Envelope: Dominant Site of Antibody Neutralization and Target for Vaccine Design

(2008) M. Montero et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS