Article
Computer Science, Artificial Intelligence
Giuseppe Pandolfo, Antonio D'Ambrosio
Summary: A non-parametric procedure based on the concept angular depth function was developed for tackling classification problems of objects in directional statistics. Different notions of depth for directional data were adopted and performances were investigated and compared through simulated and real data sets.
EXPERT SYSTEMS WITH APPLICATIONS
(2021)
Article
Engineering, Manufacturing
Yekai Yang, Chengqing Wu, Zhongxian Liu, Hai Zhang
Summary: This study presents an experimental investigation of the triaxial behavior of 3D-printing ultra-high performance fiber-reinforced concrete (3DP-UHPFRC) and compares it with mold-casting ultra-high performance fiber reinforced concrete (MC-UHPFRC). The results show that 3DP-UHPFRC has similar failure modes, mechanical properties, and failure criteria as MC-UHPFRC. Additionally, the fitting effect of the Mohr-Coulomb failure criterion on 3D-printing specimens without steel fiber is poor, while the Power-law and Willam-Warnke failure criteria are suitable for all 3D-printing specimens.
ADDITIVE MANUFACTURING
(2022)
Article
Immunology
Masoud Mortezazadeh, Saeed Kalantari, Nooshin Abolghasemi, Mitra Ranjbar, Saeedeh Ebrahimi, Abbas Mofidi, Babak Pezeshkpour, Ensieh Sadat Mansouri, Seyed Zia Tabatabaei, Mehdi Kashani
Summary: Participants were divided into two groups, one receiving probiotics treatment and the other receiving a placebo. After 3 months of treatment, the group receiving probiotics showed a significant increase in CD4+ cell count, while the group receiving placebo experienced a decrease. The study suggests that probiotics have a positive effect on improving immune function in HIV patients.
IMMUNITY INFLAMMATION AND DISEASE
(2023)
Article
Public, Environmental & Occupational Health
Qi Yan, Rui Li, YingXiao Qian, Xiao Lin, Hui Zhu, Yue Wang, Xiaoyan Zhao, Xiaohan Zhang, Qigang Sun, Qingfeng Hao, Haohai Tong, Yue Zhu, Zhitong Li, Yan Zhu, Hu Liu, Dan Huang
Summary: This study evaluated two refractive instrument-based vision screening methods, SureSight and PlusoptiX, which effectively detected refractive amblyopia risk factors and significant refractive errors in Chinese preschool children. Both methods showed good correlation with cycloplegic retinoscopy, with advantages in detecting hyperopia using SureSight and myopia using PlusoptiX. The study proposed instrumental referral criteria based on age for preschool children according to the 2021 AAPOS guidelines.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
E. Kastritis, G. Palladini, M. C. Minnema, A. D. Wechalekar, A. Jaccard, H. C. Lee, V Sanchorawala, S. Gibbs, P. Mollee, C. P. Venner, J. Lu, S. Schonland, M. E. Gatt, K. Suzuki, K. Kim, M. T. Cibeira, M. Beksac, E. Libby, J. Valent, V Hungria, S. W. Wong, M. Rosenzweig, N. Bumma, A. Huart, M. A. Dimopoulos, D. Bhutani, A. J. Waxman, S. A. Goodman, J. A. Zonder, S. Lam, K. Song, T. Hansen, S. Manier, W. Roeloffzen, K. Jamroziak, F. Kwok, C. Shimazaki, J-S Kim, E. Crusoe, T. Ahmadi, N. P. Tran, X. Qin, S. Y. Vasey, B. Tromp, J. M. Schecter, B. M. Weiss, S. H. Zhuang, J. Vermeulen, G. Merlini, R. L. Comenzo
Summary: In patients with newly diagnosed AL amyloidosis, adding daratumumab to bortezomib, cyclophosphamide, and dexamethasone resulted in higher rates of hematologic complete response and improved survival outcomes. However, adverse events, including lymphopenia, pneumonia, cardiac failure, and diarrhea, were more common in the daratumumab group. Most deaths were due to amyloidosis-related cardiomyopathy.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Energy & Fuels
Yugal Kishor, R. N. Patel, Lalit Kumar Sahu
Summary: High gain converters are widely accepted for photovoltaic (PV) integration and vehicle electrification. However, existing topologies have limited gain, input variation handling capability, and device utilization factor. This article proposes a new cascaded Z-source switched-capacitor (CZSSC) based high gain topology that overcomes these limitations and accommodates PV voltage dynamics. The study includes reliability assessment, impact analysis of parametric variation, and comparison of device stress and utilization factor. Experimental validation with a 400V/400W laboratory prototype shows the superiority of the proposed converter over similar high gain structures.
Article
Mechanics
Xunjian Hu, Yongjie Qi, Haibo Hu, Gang Lei, Ni Xie, Xiaonan Gong
Summary: A temperature-dependent initial damage or crack density parameter is proposed and a micromechanical-based failure criterion incorporating it is developed to characterize the strength properties of rocks after high-temperature treatment under compressive loading. The proposed failure criterion shows good predictive capability and provides a great description of the effect of thermally-induced damage on the strength evolution of rocks. It will be an effective alternative for predicting the nonlinear strength evolution of pre-heated rocks under compressive loading due to its high reliability and easy-to-use.
ENGINEERING FRACTURE MECHANICS
(2023)
Article
Construction & Building Technology
Xiao Jiang, Qinghua Li, Xing Yin, Shilang Xu
Summary: Ultra high toughness cementitious composites (UHTCC) with significant strain capacity and high toughness are expected to improve the performance of engineering structures. This study discusses the triaxial compressive behavior of UHTCC under different confining pressures, showing increased deviatoric strength, peak axial strain, and peak lateral strain with increasing confining pressure. The toughness index reflects the energy absorption capacity of UHTCC. UHTCC is expected to perform well in important civil and military engineering applications.
CEMENT AND CONCRETE RESEARCH
(2023)
Article
Medicine, General & Internal
Maggie Wang, Samson S. Peter, Chi D. Chu, Delphine S. Tuot, Jonathan H. Chen
Summary: The findings of this study suggest that nearly half of patients with CKD at high risk of progressing to kidney failure do not have a nephrologist visit within 1 year of established risk.
Article
Dentistry, Oral Surgery & Medicine
Amita Rai, Sunanda Sundas, Neha Dhakal, Anju Khapung
Summary: This study compared the prevalence of dental caries based on ICDAS II and WHO criteria, and found that the caries prevalence was significantly higher according to ICDAS II than WHO criteria. The presence of noncavitated carious lesions was concerning, and ICDAS II may be a more valuable tool for early/noncavitated caries diagnosis.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Article
Engineering, Biomedical
Cinzia Peruzzi, Rajaprakash Ramachandramoorthy, Alexander Groetsch, Daniele Casari, Philippe Gronquist, Markus Rueggeberg, Johann Michler, Jakob Schwiedrzik
Summary: The study found that the mechanical response of lamellar bone at the micrometer scale is similar to that at the macro scale, indicating that strain rate sensitivity is an intrinsic property of the bone extracellular matrix. Significant shear band thickening was observed at high strain rates, suggesting that the bone material is unable to accommodate the imposed deformation.
ACTA BIOMATERIALIA
(2021)
Article
Mechanics
Donat M. Takacs, Szabolcs Berezvai, Laszlo Kovacs
Summary: Modelling the static failure of fibre-reinforced composite laminates is a challenging problem due to the lack of physical interpretation for the parameters of mechanical models. To improve efficiency in designing mechanical experiments, a general method for quantifying the sensitivity of failure criteria parameters to failure stress states has been developed. This method helps select the most robust fit of model parameters by choosing failure stress states based on a failure model, and demonstrated its practical application on the Tsai-Wu and Puck failure models.
EUROPEAN JOURNAL OF MECHANICS A-SOLIDS
(2023)
Article
Mathematics, Applied
Zhentao Zhang, Jinru Wang
Summary: This paper investigates the perturbation bounds of singular subspaces under the interference of a special heteroscedastic noise matrix, and applies these methods to the heteroskedastic clustering model.
MATHEMATICAL METHODS IN THE APPLIED SCIENCES
(2022)
Review
Immunology
Md Zahidul Alam, Jeffrey R. Maslanka, Michael C. Abt
Summary: The microbiome, a complex network of microscopic organisms on and within humans, produces biologically active molecules that affect our health. Imbalances in the microbiome are associated with diseases, and new microbiome-based therapies are being developed to treat these diseases by resetting the microbiome through transplantation. The success of these therapies depends on interactions with the immune system.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Haiyan Wang, Shasha Li, Qianyu Wang, Zhengshuo Jin, Wei Shao, Yan Gao, Lu Li, Kequan Lin, Lin Zhu, Huili Wang, Xuebin Liao, Dong Wang
Summary: Combination immunotherapy using AKIs has been found to reprogram TIP gene expression, promote T cell infiltration in TNBC, and enhance the efficacy of PD-1, suggesting a novel strategy for discovering combination immunotherapy compounds.
