Journal
AICHE JOURNAL
Volume 60, Issue 9, Pages 3101-3106Publisher
WILEY
DOI: 10.1002/aic.14533
Keywords
bubbles; gas-assisted magnetic separation; low field; nanoparticles; permanent magnet
Categories
Funding
- National Natural Science Foundation of China [21106162]
- National Key Natural Science Foundation of China [21136009]
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Bubbles can be used to greatly improve the speed of magnetic separation (MS) and overcome the limitation of magnetic force on the capture distance, making low-field MS highly efficient and easily scalable. This novel method leads to the development of a medium-free continuous gas-assisted magnetic separator on small pilot scale using low-field permanent magnet. This separator is demonstrated highly efficient for recovery of proteins-loaded magnetic nanoparticles from large volume biosuspension. (C) 2014 American Institute of Chemical Engineers
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