Article
Fisheries
Mawalle Kankanamge Hasitha Madhawa Dias, E. H. T. Thulshan Jayathilaka, Shan Lakmal Edirisinghe, Jae-Woong Lim, Chamilani Nikapitiya, So Young Kang, Ilson Whang, Mahanama De Zoysa
Summary: In this study, octominin, an antimicrobial peptide derived from Octopus minor, was preliminarily tested for its antiviral activity and immune response in fish cells. The results suggest that octominin has potential as an antiviral agent, but further research is needed to understand its mechanism of action.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Maria Marinescu, Claudia-Valentina Popa
Summary: In the face of the COVID-19 pandemic, finding new compounds with antiviral and antimicrobial properties is crucial. Pyridine compounds, known for their therapeutic properties, play a significant role in defining the selectivity and interactions with target molecules. Furthermore, pyridine helps improve water solubility in medicinal chemistry. This article reviews the synthesis methods, antimicrobial and antiviral activities, pharmaceutical properties, and binding modes of pyridine compounds through Molecular Docking Studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Medicinal
Hiba Sanad, Zahira Belattmania, Ahmed Nafis, Meryem Hassouani, Noureddine Mazoir, Abdeltif Reani, Lahcen Hassani, Vitor Vasconcelos, Brahim Sabour
Summary: Volatile compounds from the marine cyanolichen Lichina pygmaea collected from the Moroccan Atlantic coast were mainly composed of sesquiterpenes compounds, with gamma-himachalene, beta-himachalene, (2E,4E)-2,4 decadienal, and alpha-himachalene as the most abundant constituents. These compounds exhibited significant antimicrobial activity against various strains and showed strong antioxidant effects.
Article
Materials Science, Multidisciplinary
Nur Ameera Rosli, Yeit Haan Teow, Ebrahim Mahmoudi
Summary: Infectious diseases caused by bacterial and viral infections are a major cause of mortality worldwide. Nanoparticles show promise as antimicrobial agents due to their multiple mechanisms of action against pathogens and low likelihood of microbial resistance development. Their utilization in various industrial applications highlights the potential for combating microbial growth and infections.
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Zehui Fang, Yuyuan Zhang, Chris Ying Cao, Quan Li Li, Hai Ming Wong
Summary: A multi-functional membrane formed by the combination of lysozyme and polyphemusin I demonstrates superior abilities in inhibiting the growth of S. mutans and inducing tooth remineralization, offering a promising strategy for preventing dental caries.
MATERIALS & DESIGN
(2022)
Article
Microbiology
Yitayal S. Anteneh, Qi Yang, Melissa H. Brown, Christopher M. M. Franco
Summary: Bacteria from marine sponges in South Australia are a rich source of diverse metabolites with antimicrobial activities against human pathogenic bacteria and fungi. A potential novel active compound with inhibitory activity against Staphylococcus aureus has been identified from one of the bacterial isolates.
Article
Engineering, Biomedical
Qiaohua Qiu, Chuan Yang, Yanming Wang, Cherylette Anne Alexander, Guangshun Yi, Yugen Zhang, Xiaohong Qin, Yi Yan Yang
Summary: This study reports on silane-functionalized polyionenes-coated cotton textiles with durable potent antimicrobial and antiviral activities. The polymers demonstrated broad-spectrum antimicrobial activity against various types of pathogenic microbes and remained effective even after multiple washings.
Article
Medicine, Research & Experimental
Milena Mattes Cerveira, Helena Silveira Vianna, Edila Maria Kickhofel Ferrer, Bruno Nunes da Rosa, Claudio Martin Pereira de Pereira, Matheus Dellamea Baldissera, Leonardo Quintana Soares Lopes, Virginia Cielo Rech, Janice Luehring Giongo, Rodrigo de Almeida Vaucher
Summary: The study found that monocurcuminoids (CNs) are a safe and effective alternative for treating microbial infections. In experiments, CNs showed growth-inhibiting effects on various strains of microbes and demonstrated non-toxicity.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Pharmacology & Pharmacy
Hatem A. Abuelizz, Rashad Al-Salahi
Summary: This review article summarizes the pharmacological activities of benzoquinazoline derivatives, including their roles as anticancer, antimicrobial, anti-depressant agents, and many others. It highlights the importance of benzoquinazolines as versatile pharmacophores for the synthesis of various pharmaceutical compounds.
PHARMACOLOGICAL REPORTS
(2023)
Review
Chemistry, Inorganic & Nuclear
Manuel Aureliano, Nadiia Gumerova, Giuseppe Sciortino, Eugenio Garribba, Annette Rompel, Debbie C. Crans
Summary: Polyoxovanadates (POVs) are a subclass of polyoxometalates (POMs) with various medicinal applications, including anticancer, antimicrobial, and antiviral activities. Studies have identified multiple mechanisms by which POVs target cancer, bacteria, and viruses.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Hanaa S. S. Gazwi, Maha O. A. Omar, Magda E. Mahmoud
Summary: This study aimed to investigate the phytoconstituents and biological activities of seed coat pea (SCP) extract. The results showed that SCP extract contains bioactive compounds such as carbohydrates, proteins, phenolics, and flavonoids. The extract exhibited antioxidant, antibacterial, anticancer, and antiviral activities. These findings are important for understanding the chemical components and antioxidant activities of pea by-products in various applications.
Article
Biophysics
Amr Hosny Hashem, Mohamed Hasanin, Samir Kamel, Sawsan Dacrory
Summary: This study prepared biocompatible, antimicrobial, and antiviral nanocomposites with promising activity against various microorganisms and HSV-1. DAC/GO/Cys and DAC/GO/Meth showed the most potential antimicrobial activity, while DAC/GO/Cys/Meth exhibited the lowest. Computational procedures and molecular docking demonstrated that DAC incorporation with amino acids enhanced their reactivity and interaction.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Fisheries
Jhonatas Teixeira Viana, Rafael dos Santos Rocha, Rodrigo Maggioni
Summary: Lectins are important pattern recognition receptors in the immune system of L. vannamei, involved in multiple immune response pathways.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Pharmacology & Pharmacy
Mary Zoepfl, Rohini Dwivedi, Maggie C. Taylor, Vitor H. Pomin, Michael A. McVoy
Summary: The need for broad-spectrum antivirals is increasing, especially for novel emerging viruses and those with limited treatment options or resistance. Research has shown that specific marine sulfated glycans can inhibit viral attachment and entry, potentially through interactions with virions, suggesting unique opportunities for exploring relationships between glycan structure and antiviral activities.
ANTIVIRAL RESEARCH
(2021)
Article
Chemistry, Medicinal
Loredana Stabili, Lucia Rizzo, Rosa Caprioli, Antonella Leone, Stefano Piraino
Summary: The study focused on investigating the antioxidant and lysozyme antibacterial activities associated with extracts from different parts of A. coerulea. Extracts from the oral arms of A. coerulea showed significant antioxidant activity and the highest lysozyme-like activity, suggesting their potential as a source of novel cytolytic and cytotoxic products against marine bacteria. The wide geographic distribution and seasonal abundance of A. coerulea populations in coastal waters support the exploration of biotechnological applications of jellyfish biomasses in pharmaceutical, nutritional, and nutraceutical sectors.
