Hypoxia disrupts proteostasis inCaenorhabditis elegans

Novel Polyglutamine Model Uncouples Proteotoxicity from Aging

(2014) Nakeirah T. M. Christie et al.   PLoS One

A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity

(2013) Tayir El-Ami et al.   AGING CELL

XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity

(2013) Rebecca C. Taylor et al.   CELL

Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1

(2013) Scott F. Leiser et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease

(2012) Cora O'Neill et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dual effects of hydrogen sulphide on focal cerebral ischaemic injury via modulation of oxidative stress-induced apoptosis

(2012) Guo-Feng Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Heat Shock and Caloric Restriction Have a Synergistic Effect on the Heat Shock Response in asir2.1-dependent Manner inCaenorhabditis elegans

(2012) Rachel Raynes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

(2012) David Vilchez et al.   NATURE

CYSL-1 Interacts with the O2-Sensing Hydroxylase EGL-9 to Promote H2S-Modulated Hypoxia-Induced Behavioral Plasticity in C. elegans

(2012) Dengke K. Ma et al.   NEURON

Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning

(2012) K. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress and aging induce distinct polyQ protein aggregation states

(2012) L. E. Moronetti Mazzeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

(2011) Louis R. Lapierre et al.   CURRENT BIOLOGY

Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury

(2011) Adrienne L. King et al.   EXPERIMENTAL PHYSIOLOGY

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Long term changes in phospho-APP and tau aggregation in the 3xTg-AD mice following cerebral ischemia

(2011) M.A. Koike et al.   NEUROSCIENCE LETTERS

HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans

(2011) Dana L. Miller et al.   PLoS One

Aging as an Event of Proteostasis Collapse

(2011) R. C. Taylor et al.   Cold Spring Harbor Perspectives in Biology

A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network

(2011) M. Catarina Silva et al.   PLoS Genetics

Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning

(2010) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hypoxia-Inducible Factor-1α Is Involved in the Pro-angiogenic Effect of Hydrogen Sulfide under Hypoxic Stress

(2010) XinHua Liu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Protein homeostasis and aging in neurodegeneration

(2010) Peter M. Douglas et al.   JOURNAL OF CELL BIOLOGY

Alpha-Synuclein Aggregation Induced by Brief Ischemia Negatively Impacts Neuronal Survival in vivo: A Study in [A30P]alpha-Synuclein Transgenic Mouse

(2010) Isin Unal-Cevik et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lifespan and oxidative stress show a non-linear response to atmospheric oxygen in Drosophila

(2010) B. Rascon et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery

(2010) X. R. Mao et al.   MOLECULAR AND CELLULAR BIOLOGY

Hydrogen sulfide and ischemia–reperfusion injury

(2010) Chad K. Nicholson et al.   PHARMACOLOGICAL RESEARCH

Hypoxia signaling and resistance in C. elegans

(2010) Jo Anne Powell-Coffman   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hydrogen sulfide-mediated myocardial pre- and post-conditioning

(2010) Benjamin L Predmore et al.   Expert Review of Clinical Pharmacology

C. Elegans Are Protected from Lethal Hypoxia by an Embryonic Diapause

(2009) Dana L. Miller et al.   CURRENT BIOLOGY

Metabolic function in Drosophila melanogaster in response to hypoxia and pure oxygen

(2009) W. A. Van Voorhies   JOURNAL OF EXPERIMENTAL BIOLOGY

Hydrogen Sulfide Increases Hypoxia-inducible Factor-1 Activity Independently of von Hippel–Lindau Tumor Suppressor-1 in C. elegans

(2009) Mark W. Budde et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

Proteasomal Regulation of the Hypoxic Response Modulates Aging in C. elegans

(2009) R. Mehta et al.   SCIENCE