RNA-seq of the aging brain in the short-lived fishN. furzeri- conserved pathways and novel genes associated with neurogenesis

Notch1 signaling modulates neuronal progenitor activity in the subventricular zone in response to aging and focal ischemia

(2013) Fen Sun et al.   AGING CELL

Life spanning murine gene expression profiles in relation to chronological and pathological aging in multiple organs

(2013) Martijs J. Jonker et al.   AGING CELL

Parallel evolution of senescence in annual fishes in response to extrinsic mortality

(2013) Eva Terzibasi Tozzini et al.   BMC EVOLUTIONARY BIOLOGY

The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels

(2013) Andreas Petzold et al.   BMC GENOMICS

Real-time in vivo monitoring of circadian E-box enhancer activity: A robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock

(2013) Meltem Weger et al.   DEVELOPMENTAL BIOLOGY

Increased radial glia quiescence, decreased reactivation upon injury and unaltered neuroblast behavior underlie decreased neurogenesis in the aging zebrafish telencephalon

(2013) Kathrin Edelmann et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

Widespread splicing changes in human brain development and aging

(2013) P. Mazin et al.   Molecular Systems Biology

CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness

(2013) Bruno Pereira et al.   NUCLEIC ACIDS RESEARCH

Rapid growth, early maturation and short generation time in African annual fishes

(2013) Radim Blažek et al.   EvoDevo

Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome

(2012) Shona H. Wood et al.   AGE

DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex

(2012) Shusuke Numata et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nonoverlapping Functions of the Polycomb Group Cbx Family of Proteins in Embryonic Stem Cells

(2012) Lluis Morey et al.   Cell Stem Cell

Age-Associated Hyper-Methylated Regions in the Human Brain Overlap with Bivalent Chromatin Domains

(2012) Corey T. Watson et al.   PLoS One

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

Mitochondrial DNA copy number and function decrease with age in the short-lived fishNothobranchius furzeri

(2011) Nils Hartmann et al.   AGING CELL

Adult neurogenesis in the short-lived teleost Nothobranchius furzeri: localization of neurogenic niches, molecular characterization and effects of aging

(2011) Eva Terzibasi Tozzini et al.   AGING CELL

Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri- a new vertebrate model for age research

(2011) Jeanette Kirschner et al.   AGING CELL

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging

(2010) Sebastian Lugert et al.   Cell Stem Cell

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

(2010) Ruth Beckervordersandforth et al.   Cell Stem Cell

The short-lived annual fish Nothobranchius furzeri shows a typical teleost aging process reinforced by high incidence of age-dependent neoplasias

(2010) Emiliano Di Cicco et al.   EXPERIMENTAL GERONTOLOGY

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

(2010) M. Somel et al.   GENOME RESEARCH

Notch Activity Levels Control the Balance between Quiescence and Recruitment of Adult Neural Stem Cells

(2010) P. Chapouton et al.   JOURNAL OF NEUROSCIENCE

Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

(2010) H. Wu et al.   SCIENCE

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

(2009) Rebecca Favaro et al.   NATURE NEUROSCIENCE

Effect of aging on neurogenesis in the canine brain

(2008) Anton Pekcec et al.   AGING CELL

Early age-related changes in adult hippocampal neurogenesis in C57 mice

(2008) Nada M.-B. Ben Abdallah et al.   NEUROBIOLOGY OF AGING

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

(2008) Patrick M. Loerch et al.   PLoS One

Large Differences in Aging Phenotype between Strains of the Short-Lived Annual Fish Nothobranchius furzeri

(2008) Eva Terzibasi et al.   PLoS One