Shc depletion stimulates brown fat activityin vivoandin vitro

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Yes, even human brown fat is on fire!

(2012) Barbara Cannon et al.   JOURNAL OF CLINICAL INVESTIGATION

Programming human pluripotent stem cells into white and brown adipocytes

(2012) Tim Ahfeldt et al.   NATURE CELL BIOLOGY

SR59230A, a beta-3 adrenoceptor antagonist, inhibits ultradian brown adipose tissue thermogenesis and interrupts associated episodic brain and body heating

(2011) Youichirou Ootsuka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Differential Signaling by Adaptor Molecules LRP1 and ShcA Regulates Adipogenesis by the Insulin-like Growth Factor-1 Receptor

(2011) Estelle Woldt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brown Adipose Tissue in Morbidly Obese Subjects

(2011) Guy H. E. J. Vijgen et al.   PLoS One

The Shc locus regulates insulin signaling and adiposity in mammals

(2010) Alexey A. Tomilov et al.   AGING CELL

Brown adipose tissue in humans

(2010) Kirsi A Virtanen et al.   CURRENT OPINION IN LIPIDOLOGY

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

(2010) S. C. Ranieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Associated Increase in Abdominal Obesity and Insulin Resistance, and Usefulness of AHA/NHLBI Definition of Metabolic Syndrome for Predicting Cardiovascular Disease in Japanese Elderly with Type 2 Diabetes Mellitus

(2009) Takashi Sakurai et al.   GERONTOLOGY

Metabolic Syndrome and Physical Decline in Older Persons: Results from the Health, Aging and Body Composition Study

(2009) B. W. J. H. Penninx et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brown Fat and Skeletal Muscle: Unlikely Cousins?

(2008) Stephen R. Farmer   CELL

p66ShcDeletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice

(2008) Ines Martin-Padura et al.   ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH

p66Shc-generated Oxidative Signal Promotes Fat Accumulation

(2008) Ina Berniakovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Central obesity and increased risk of dementia more than three decades later

(2008) R. A. Whitmer et al.   NEUROLOGY