Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP

Axonal Transport and Mitochondrial Dysfunction in Alzheimer's Disease

(2012) Jan Riemer et al.   Neurodegenerative Diseases

Possible roles of amyloid intracellular domain of amyloid precursor protein

(2011) Keun-A Chang et al.   BMB Reports

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

(2011) Baiyang Sheng et al.   JOURNAL OF NEUROCHEMISTRY

Nuclear Control of Respiratory Chain Expression by Nuclear Respiratory Factors and PGC-1-Related Coactivator

(2010) Richard C. Scarpulla   Annals of the New York Academy of Sciences

The amyloid precursor protein intracellular domain (AICD) disrupts actin dynamics and mitochondrial bioenergetics

(2010) Manus W. Ward et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and/or transcriptional role - relevance for Alzheimer pathology

(2010) Gennaro Schettini et al.   JOURNAL OF NEUROCHEMISTRY

PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

(2009) Weiping Qin et al.   ARCHIVES OF NEUROLOGY

Accumulation of Phosphorylated β-Catenin Enhances ROS-Induced Cell Death in Presenilin-Deficient Cells

(2009) Jung H. Boo et al.   PLoS One

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward Structural Elucidation of the γ-Secretase Complex

(2009) Huilin Li et al.   STRUCTURE

Sequence analyses of presenilin mutations linked to familial Alzheimer’s disease

(2008) Sun Don Kim et al.   CELL STRESS & CHAPERONES

The Catalytic Core of γ-Secretase: Presenilin Revisited

(2008) Harald Steiner   Current Alzheimer Research

Presenilin: RIP and beyond

(2008) Matthew R. Hass et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The FE65 proteins and Alzheimer's disease

(2007) Declan M. McLoughlin et al.   JOURNAL OF NEUROSCIENCE RESEARCH