An age-related numerical and functional deficit in CD19+CD24hiCD38hiB cells is associated with an increase in systemic autoimmunity

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Unknown

(2012) Matthew Klinker et al.   MOLECULAR MEDICINE

Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age

(2012) M. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly

(2011) Feng Qian et al.   AGING CELL

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

Mice Lacking Endogenous IL-10-Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells

(2011) N. A. Carter et al.   JOURNAL OF IMMUNOLOGY

Preserved ex vivo inflammatory status and cytokine responses in naturally long-lived mice

(2010) Lorena Arranz et al.   AGE

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

Signaling via the MyD88 Adaptor Protein in B Cells Suppresses Protective Immunity during Salmonella typhimurium Infection

(2010) Patricia Neves et al.   IMMUNITY

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

(2010) Alexander Panda et al.   JOURNAL OF IMMUNOLOGY

Rheumatoid Arthritis: A Role for Immunosenescence?

(2010) Tamsin M. Lindstrom et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

(2009) K. Yanaba et al.   JOURNAL OF IMMUNOLOGY

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY

B cells and aging: molecules and mechanisms

(2009) Michael P. Cancro et al.   TRENDS IN IMMUNOLOGY

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

B-lymphocyte contributions to human autoimmune disease

(2008) Koichi Yanaba et al.   IMMUNOLOGICAL REVIEWS

Aged B lymphocytes retain their ability to express surface markers but are dysfunctional in their proliferative capability during early activation events

(2008) Anthony Blaeser et al.   Immunity & Ageing