HIV protease inhibitors induce senescence and alter osteoblastic potential of human bone marrow mesenchymal stem cells: beneficial effect of pravastatin

Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects

(2012) MiJung Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Sp1 Transcription Factor Interaction with Accumulated Prelamin A Impairs Adipose Lineage Differentiation in Human Mesenchymal Stem Cells: Essential Role of Sp1 in the Integrity of Lipid Vesicles

(2012) Garbiñe Ruiz de Eguino et al.   Stem Cells Translational Medicine

Osteoporosis and Bone Health in HIV

(2012) William G. Powderly   Current HIV/AIDS Reports

Peripheral and Central Fat Changes in Subjects Randomized to Abacavir-Lamivudine or Tenofovir-Emtricitabine With Atazanavir-Ritonavir or Efavirenz: ACTG Study A5224s

(2011) G. A. McComsey et al.   CLINICAL INFECTIOUS DISEASES

Premature Aging and Premature Age-Related Comorbidities in HIV-Infected Patients: Facts and Hypotheses

(2011) J. Capeau   CLINICAL INFECTIOUS DISEASES

Suppression of lamin A/C by short hairpin RNAs promotes adipocyte lineage commitment in mesenchymal progenitor cell line, ROB-C26

(2011) Masako Naito et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Stable Bone Density in HAART-Treated Individuals with HIV: A Meta-Analysis

(2011) Mark J. Bolland et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Treatment With Pravastatin Attenuates Oxidative Stress and Protects Osteoblast Cell Viability From Indoxyl Sulfate

(2011) Yoshiko Iwasaki et al.   THERAPEUTIC APHERESIS AND DIALYSIS

HIV Type 1 Alters Mesenchymal Stem Cell Differentiation Potential and Cell Phenotype ex Vivo

(2010) Eoin J. Cotter et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Drug-induced Osteoporosis: Mechanisms and Clinical Implications

(2010) Gherardo Mazziotti et al.   AMERICAN JOURNAL OF MEDICINE

HIV and bone disease

(2010) Benjamin Stone et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Premature Senescence of Vascular Cells Is Induced by HIV Protease Inhibitors

(2010) Chloé Lefèvre et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bone mineral density changes in protease inhibitor-sparing vs. nucleoside reverse transcriptase inhibitor-sparing highly active antiretroviral therapy: data from a randomized trial*

(2010) AB Hansen et al.   HIV MEDICINE

Dynamics of Lamin-A Processing Following Precursor Accumulation

(2010) Qian Liu et al.   PLoS One

HIV-associated lipodystrophy: from fat injury to premature aging

(2010) Martine Caron-Debarle et al.   TRENDS IN MOLECULAR MEDICINE

Greater decrease in bone mineral density with protease inhibitor regimens compared with nonnucleoside reverse transcriptase inhibitor regimens in HIV-1 infected naive patients

(2009) Claudine Duvivier et al.   AIDS

Continuous antiretroviral therapy decreases bone mineral density

(2009) Birgit Grund et al.   AIDS

Accelerated Features of Age-Related Bone Loss in Zmpste24 Metalloproteinase-Deficient Mice

(2009) D. Rivas et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts

(2008) Shuanhu Zhou et al.   AGING CELL

Effects of boosted tipranavir and lopinavir on body composition, insulin sensitivity and adipocytokines in antiretroviral-naive adults

(2008) Andrew Carr et al.   AIDS

Statins: under investigation for increasing bone mineral density and augmenting fracture healing

(2008) Quen Oak Tang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effect of Lamin A/C Knockdown on Osteoblast Differentiation and Function

(2008) Rahima Akter et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Fracture Prevalence among Human Immunodeficiency Virus (HIV)-InfectedVersusNon-HIV-Infected Patients in a Large U.S. Healthcare System

(2008) Virginia A. Triant et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

(2008) Ignacio Varela et al.   NATURE MEDICINE