Modulation of methuselah expression targeted toDrosophilainsulin-producing cells extends life and enhances oxidative stress resistance

Interplay between FOXO, TOR, and Akt

(2011) Nissim Hay   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SH2B Regulation of Growth, Metabolism, and Longevity in Both Insects and Mammals

(2010) Wei Song et al.   Cell Metabolism

BlockingO-Linked GlcNAc Cycling inDrosophilaInsulin-producing Cells Perturbs Glucose-Insulin Homeostasis

(2010) Osamu Sekine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila

(2009) Jason Karpac et al.   AGING CELL

Insulin/IGF-like signalling, the central nervous system and aging

(2009) Susan Broughton et al.   BIOCHEMICAL JOURNAL

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

TheDrosophilaG protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides

(2009) William W. Ja et al.   PROTEIN SCIENCE

Insulin and JNK: optimizing metabolic homeostasis and lifespan

(2009) Jason Karpac et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

Reduction of DILP2 in Drosophila Triages a Metabolic Phenotype from Lifespan Revealing Redundancy and Compensation among DILPs

(2008) Susan Broughton et al.   PLoS One

Drosophila germ-line modulation of insulin signaling and lifespan

(2008) T. Flatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA