β1-Adrenergic receptor blockade extends the life span of Drosophila and long-lived mice

Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity

(2012) Ling Zhao et al.   AGING CELL

Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

(2012) Stephen R. Spindler et al.   PLoS One

Statin Treatment Increases Lifespan and Improves Cardiac Health in Drosophila by Decreasing Specific Protein Prenylation

(2012) Stephen R. Spindler et al.   PLoS One

Expression of β-adrenergic-like Octopamine Receptors duringDrosophilaDevelopment

(2012) Yuya Ohhara et al.   ZOOLOGICAL SCIENCE

Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span

(2011) Stephen Richard Spindler   AGE

Pharmacogenetics of β2 adrenergic receptor gene polymorphisms, long-acting β-agonists and asthma

(2011) L. P. Chung et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Nebivolol Exerts Beneficial Effects on Endothelial Function, Early Endothelial Progenitor Cells, Myocardial Neovascularization, and Left Ventricular Dysfunction Early After Myocardial Infarction Beyond Conventional β1-Blockade

(2011) Sajoscha A. Sorrentino et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Previously unsuspected widespread cellular and tissue distribution of β-adrenoceptors and its relevance to drug action

(2011) C.J. Daly et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Modulation of β-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5

(2010) David Ho et al.   HEART FAILURE REVIEWS

Expression of β2-adrenergic receptor in oral squamous cell carcinoma

(2010) Zheng Jun Shang et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Intracellular mechanisms of specific β-adrenoceptor antagonists involved in improved cardiac function and survival in a genetic model of heart failure

(2008) Jan B. Bartholomeu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nebivolol, but Not Metoprolol, Improves Endothelial Function of the Corpus Cavernosum in Apolipoprotein E-Knockout Mice

(2008) M. Baumhakel et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL