Naïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirus

Thymic function failure and C-reactive protein levels are independent predictors of all-cause mortality in healthy elderly humans

(2011) Sara Ferrando-Martínez et al.   AGE

Relationship between cytomegalovirus (CMV) IgG serology, detectable CMV DNA in peripheral monocytes, and CMV pp65495–503-specific CD8+ T cells in older adults

(2011) Sean X. Leng et al.   AGE

Cytomegalovirus: pathogen, paradigm, and puzzle

(2011) Michael Boeckh et al.   JOURNAL OF CLINICAL INVESTIGATION

Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans

(2011) E. Derhovanessian et al.   JOURNAL OF GENERAL VIROLOGY

Functional CD8 T Cell Memory Responding to Persistent Latent Infection Is Maintained for Life

(2011) A. Lang et al.   JOURNAL OF IMMUNOLOGY

Cytomegalovirus-Specific T Cell Immunity Is Maintained in Immunosenescent Rhesus Macaques

(2011) L. Cicin-Sain et al.   JOURNAL OF IMMUNOLOGY

Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

(2011) R. Lachmann et al.   JOURNAL OF VIROLOGY

Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets

(2011) Nicolle HR Litjens et al.   Immunity & Ageing

Age-related deregulation of naive T cell homeostasis in elderly humans

(2010) Sara Ferrando-Martínez et al.   AGE

Latent Cytomegalovirus infection amplifies CD8 T-lymphocyte mobilisation and egress in response to exercise

(2010) James E. Turner et al.   BRAIN BEHAVIOR AND IMMUNITY

Cytomegalovirus gN Genotypes Distribution among Congenitally Infected Newborns and Their Relationship with Symptoms at Birth and Sequelae

(2010) Sara Pignatelli et al.   CLINICAL INFECTIOUS DISEASES

The emerging role of cytomegalovirus in driving immune senescence: a novel therapeutic opportunity for improving health in the elderly

(2010) Paul Moss   CURRENT OPINION IN IMMUNOLOGY

Human cytomegalovirus-specific CD8+ T-cell expansions contain long-lived cells that retain functional capacity in both young and elderly subjects

(2010) Diana L. Wallace et al.   IMMUNOLOGY

Intense Antiextracellular Adaptive Immune Response to Human Cytomegalovirus in Very Old Subjects with Impaired Health and Cognitive and Functional Status

(2010) R. Vescovini et al.   JOURNAL OF IMMUNOLOGY

Hallmark Features of Immunosenescence Are Absent in Familial Longevity

(2010) E. Derhovanessian et al.   JOURNAL OF IMMUNOLOGY

Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool

(2010) P. J. E. J. van de Berg et al.   JOURNAL OF IMMUNOLOGY

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

(2010) Graham Pawelec et al.   Immunity & Ageing

Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals

(2009) S. Chidrawar et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunosenescence: what does it mean to health outcomes in older adults?

(2009) Janet E McElhaney et al.   CURRENT OPINION IN IMMUNOLOGY

Reduced thymus activity and infection prematurely age the immune system

(2009) Ronald E. Gress et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence of premature immune aging in patients thymectomized during early childhood

(2009) Delphine Sauce et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflation and Long-Term Maintenance of CD8 T Cells Responding to a Latent Herpesvirus Depend upon Establishment of Latency and Presence of Viral Antigens

(2009) A. Lang et al.   JOURNAL OF IMMUNOLOGY

Clonotype Selection and Composition of Human CD8 T Cells Specific for Persistent Herpes Viruses Varies with Differentiation but Is Stable Over Time

(2009) E. M. Iancu et al.   JOURNAL OF IMMUNOLOGY

CD28− T cells: their role in the age-associated decline of immune function

(2009) Nan-ping Weng et al.   TRENDS IN IMMUNOLOGY

Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors

(2009) María Pita-Lopez et al.   Immunity & Ageing

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

(2008) Christopher M. Snyder et al.   IMMUNITY

Maintenance of Large Subpopulations of Differentiated CD8 T-Cells Two Years after Cytomegalovirus Infection in Gambian Infants

(2008) David J. C. Miles et al.   PLoS One

A fingerprint left by cytomegalovirus infection in the human T cell compartment

(2007) Pablo J.E.J. van de Berg et al.   JOURNAL OF CLINICAL VIROLOGY