Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

(2011) Joris Deelen et al.   AGING CELL

Gene set analysis of SNP data: benefits, challenges, and future directions

(2011) Brooke L Fridley et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Replication of Extended Lifespan Phenotype in Mice with Deletion of Insulin Receptor Substrate 1

(2011) Colin Selman et al.   PLoS One

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

(2010) Mette Soerensen et al.   AGING CELL

Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data

(2010) Lin S. Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide gene and pathway analysis

(2010) Li Luo et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The association of telomere length and genetic variation in telomere biology genesa

(2010) Lisa Mirabello et al.   HUMAN MUTATION

A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

(2010) Anne B. Newman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Common variants near TERC are associated with mean telomere length

(2010) Veryan Codd et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics

(2010) J. A. Blake et al.   NUCLEIC ACIDS RESEARCH

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

(2010) D. Levy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Web-Based, Participant-Driven Studies Yield Novel Genetic Associations for Common Traits

(2010) Nicholas Eriksson et al.   PLoS Genetics

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

(2009) Ludmila Pawlikowska et al.   AGING CELL

The SNP ratio test: pathway analysis of genome-wide association datasets

(2009) Colm O'Dushlaine et al.   BIOINFORMATICS

Asymptotic tests of association with multiple SNPs in linkage disequilibrium

(2009) Wei Pan   GENETIC EPIDEMIOLOGY

A genome-wide association study of acenocoumarol maintenance dosage

(2009) Martina Teichert et al.   HUMAN MOLECULAR GENETICS

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations

(2009) Yang Li et al.   HUMAN MOLECULAR GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians

(2009) G. Atzmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study

(2009) Chiara Viviani Anselmi et al.   REJUVENATION RESEARCH

Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins

(2008) M. Kimura et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Engineered telomere degradation models dyskeratosis congenita

(2008) D. Hockemeyer et al.   GENES & DEVELOPMENT

Analysis of multiple SNPs in a candidate gene or region

(2008) Juliet Chapman et al.   GENETIC EPIDEMIOLOGY

Pathway analysis of seven common diseases assessed by genome-wide association

(2008) Ali Torkamani et al.   GENOMICS

A HapMap harvest of insights into the genetics of common disease

(2008) Teri A. Manolio et al.   JOURNAL OF CLINICAL INVESTIGATION

Pot1b Deletion and Telomerase Haploinsufficiency in Mice Initiate an ATR-Dependent DNA Damage Response and Elicit Phenotypes Resembling Dyskeratosis Congenita

(2008) H. He et al.   MOLECULAR AND CELLULAR BIOLOGY

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA