How pleiotropic genetics of the musculoskeletal system can inform genomics and phenomics of aging

Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture

(2013) J. Brent Richards   ANNALS OF INTERNAL MEDICINE

A Physiologic Index of Comorbidity: Relationship to Mortality and Disability

(2011) A. B. Newman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

(2010) Anne B. Newman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

Skeletal Muscle and Mortality Results From the InCHIANTI Study

(2009) M. Cesari et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Human genetic variations: Beacons on the pathways to successful ageing

(2009) Christie Cluett et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

Phenomics: the systematic study of phenotypes on a genome-wide scale

(2009) R.M. Bilder et al.   NEUROSCIENCE

Genetic Variation in Healthy Oldest-Old

(2009) Julius Halaschek-Wiener et al.   PLoS One

Powerful Bivariate Genome-Wide Association Analyses Suggest the SOX6 Gene Influencing Both Obesity and Osteoporosis Phenotypes in Males

(2009) Yao-Zhong Liu et al.   PLoS One

RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans

(2009) Paola Sebastiani et al.   PLoS One

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee

(2009) A. J. MacGregor et al.   RHEUMATOLOGY

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size

(2009) Nicole Soranzo et al.   PLoS Genetics

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2009) Cecilia M. Lindgren et al.   PLoS Genetics

Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis

(2008) C S Zipitis et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation

(2008) Andrew M Ho et al.   BMC DEVELOPMENTAL BIOLOGY

Activation of Sirt1 Decreases Adipocyte Formation during Osteoblast Differentiation of Mesenchymal Stem Cells

(2008) Carl-Magnus Bäckesjö et al.   CELLS TISSUES ORGANS

Vitamin D Deficiency and Risk of Cardiovascular Disease

(2008) Thomas J. Wang et al.   CIRCULATION

Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men

(2008) Karri Silventoinen et al.   GENETIC EPIDEMIOLOGY

Osteoporosis: an evolutionary perspective

(2008) David Karasik   HUMAN GENETICS

Genetics of the Musculoskeletal System: A Pleiotropic Approach

(2008) David Karasik et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Functional Adaptation to Loading of a Single Bone Is Neuronally Regulated and Involves Multiple Bones

(2008) Janet Rubin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Successful Skeletal Aging: A Marker of Low Fracture Risk and Longevity. The Study of Osteoporotic Fractures (SOF)

(2008) Jane A Cauley et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bivariate Genome-Wide Linkage Analysis of Femoral Bone Traits and Leg Lean Mass: Framingham Study

(2008) David Karasik et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Serum Osteocalcin Level Is Associated with Glucose Metabolism and Atherosclerosis Parameters in Type 2 Diabetes Mellitus

(2008) Ippei Kanazawa et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

(2008) Y. Rolland et al.   Journal of Nutrition Health & Aging

CHIP Deficiency Decreases Longevity, with Accelerated Aging Phenotypes Accompanied by Altered Protein Quality Control

(2008) J.-N. Min et al.   MOLECULAR AND CELLULAR BIOLOGY

Endocrine alterations in response to calorie restriction in humans

(2008) Leanne M. Redman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Common variants in the GDF5-UQCC region are associated with variation in human height

(2008) Serena Sanna et al.   NATURE GENETICS

Genome-wide association analysis identifies 20 loci that influence adult height

(2008) Michael N Weedon et al.   NATURE GENETICS

Quantitative Trait Loci for Bone Lengths on Chromosome 5 Using Dual Energy X-Ray Absorptiometry Imaging in the Twins UK Cohort

(2008) Usha Chinappen-Horsley et al.   PLoS One

Genetics of Maximal Walking Speed and Skeletal Muscle Characteristics in Older Women

(2008) Kristina M. Tiainen et al.   Twin Research and Human Genetics

The androgen receptor and prostate cancer: A role for sexual selection and sexual conflict?

(2007) Kyle Summers et al.   MEDICAL HYPOTHESES