Article
Veterinary Sciences
Lixin Xu, Quanjia Xiang, Mongqi Li, Xiaoting Sun, Mingmin Lu, Ruofeng Yan, Xiaokai Song, Xiangrui Li
Summary: This study evaluated the effects of Eimeria mitis on Eimeria necatrix or Eimeria tenella infection and found that the presence of E. mitis exacerbated the outcome of co-infection with E. tenella. However, it had little impact on the infection outcome of E. necatrix. These results suggest the importance of considering the relationships among different Eimeria species when using mixed infection models.
VETERINARY SCIENCES
(2022)
Article
Mathematics
Marin Marin, Aatef Hobiny, Ibrahim Abbas
Summary: In this work, numerical estimations for a nonlinear hyperbolic bioheat equation were constructed for medicinal treatments of tumor cells. The study considered the experimental temperature-dependent functions of heating source components in the model. The finite element method was used to solve the nonlinear problem, and parametric analysis was conducted to enhance the accuracy of thermal power in hyperthermia treatments.
Article
Immunology
Basile Konmy, Pascal Abiodoun Olounlade, Tomabu Adjobimey, Christian Cocou Dansou, Akouavi Carine Chimene Adoho, Esaie Tchetan, Georcelin Goue Alowanou, Erick Virgile Bertrand Azando, Adolphe Adjanohoun, Sanni-yo Doko Allou, Lamine Baba-Moussa
Summary: The immune response and anticoccidial activity induced by Moringa oleifera and Vernonia amygdalina leaves in rabbits infected with Eimeria magna and Eimeria media were investigated. The results showed that the acetone extract of Moringa oleifera and Vernonia amygdalina at 1000 mg/kg bw had an in vivo efficacy of 95.43% and 96.53% against E. magna and E. media oocysts, respectively. Moreover, the plant extracts increased the production of interleukin (IL) and immunoglobulins (Ig) compared to controls. These findings suggest that Moringa oleifera and Vernonia amygdalina can be used as alternative anticoccidials and improve the immune system resistance of rabbits to Eimeria infestations.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Immunology
Xu Yuan, Xiaofen Hu, Shanshan Yang, Shengwei Zhong, Tingyu Yang, Yunxiao Zhou, Yong Li
Summary: This study investigated the metabolic alterations and pathways in rabbits infected with E. intestinalis and E. magna. The results showed that the infection of these parasites led to changes in the intestinal flora and corresponding metabolites. The dysregulated pathways mainly involved lipid metabolism and the endocrine system.
MICROBIAL PATHOGENESIS
(2022)
Review
Immunology
Rafael Cardoso Maciel Costa Silva, Jhones Sousa Ribeiro, Gustavo Peixoto Duarte da Silva, Luciana Jesus da Costa, Leonardo Holanda Travassos
Summary: This article discusses the interplay between coronaviruses and autophagy, highlighting the mechanisms by which autophagy restrains inflammatory responses involved in coronavirus pathogenesis. It also explores different autophagy modulators and the rationale for drug repurposing as an attractive adjunctive therapy.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Parasitology
Xu Yuan, Jin Liu, Xiaofen Hu, Shanshan Yang, Shengwei Zhong, Tingyu Yang, Yunxiao Zhou, Guotong Zhao, Yijie Jiang, Yong Li
Summary: This study revealed that Eimeria intestinalis infection induced intestinal inflammation and significant changes in the gut microbiota and metabolites in rabbits, disrupting intestinal homeostasis.
PARASITES & VECTORS
(2022)
Article
Emergency Medicine
Jack Silva, Reynold Henry, Matthieu Strickland, Dandan Wang, Kazuhide Matsushima
Summary: Clostridium sordellii infections, particularly in injection drug users, can lead to rapidly fatal necrotizing soft tissue infections. Despite treatment with antibiotics and surgical debridement, the infection may progress quickly and be difficult to manage.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Immunology
Xiao-Di Chen, Jing Xie, Yong Wei, Ji-Feng Yu, Ye Cao, Lu Xiao, Xue-Jing Wu, Cong-Jian Mao, Run-Min Kang, Yong-Gang Ye
Summary: Despite long-term control efforts, hepatic coccidiosis caused by Eimeria stiedai infection remains persistent in rabbits in China. This study provides the first evidence of changes in Th1/Th2/Treg/Th17/Th9/Th21 cells in rabbits infected with E. stiedai, offering insights into immune regulation mechanisms and potential vaccine development.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
Rewaida Abdel-Gaber, Saleh Al Quraishy, Nawal Al-Hoshani, Tahani Al-Otaibi, Sawsan A. Omer, Fatemah Alajmi, Mohamed Dkhil, Esam M. Al-Shaebi, Osama B. Mohammed
Summary: This study established the morphological and molecular characteristics of Eimeria media and Eimeria stiedai infections in rabbits in Saudi Arabia, which had limited information and weak molecular data. The study emphasized the significance of combining taxonomy with morphological and genetic data in the identification of Eimeria species.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Parasitology
Jie Xiao, Wei He, Changming Xiong, Ge Hao, Jiayan Pu, Hao Chen, Liwen Xu, Yuhua Zhu, Yongjun Ren, Guangyou Yang
Summary: The surface proteins rEiIMP1 and rEiAMA1 from Eimeria intestinalis show good immunoreactivity and immunoprotective effects, making them potential candidate vaccine antigens against this pathogen.
VETERINARY PARASITOLOGY
(2023)
Article
Immunology
Svenja Barth, Susanne Kirschnek, Noemi Ortmann, Yakup Tanriver, Georg Haecker
Summary: The study found that ILC1 increased continuously during Chlamydia infection in a mouse model, while the numbers of ILC2 and ILC3 fluctuated significantly. Most ILC3s would transdifferentiate into ILC1s, and both NK cells and ILC1s produced interferon and a small amount of tumor necrosis factor in early infection. Lack of B and T cells increased ILC numbers, while the absence of myeloid cells decreased them.
INFECTION AND IMMUNITY
(2021)
Article
Medicine, General & Internal
Vasiliki Mamali, Christos Koutserimpas, Kassiani Manoloudaki, Olympia Zarkotou, George Samonis, Georgia Vrioni
Summary: This article presents a rare case of fungal necrotizing skin and soft tissue infection, which was successfully treated through surgical debridements and antifungal therapy. The infection occurred in an immunocompetent individual, highlighting the importance of early diagnosis and appropriate treatment.
Review
Immunology
Zhongyu Han, Kuai Ma, Hongxia Tao, Hongli Liu, Jiong Zhang, Xiyalatu Sai, Yunlong Li, Mingxuan Chi, Qing Nian, Linjiang Song, Chi Liu
Summary: Kidney disease has seen a dramatic increase in prevalence over the past few decades. Treg cell metabolism plays a critical role in kidney diseases by regulating the function and proliferation of Treg cells. Targeting metabolic pathways may offer a promising approach for the treatment of kidney disease.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Veterinary Sciences
Baohong Liu, Xueting Ma, Jianping Cai
Summary: In this study, gene coexpression network analysis was used to identify modules associated with Eimeria tenella infection in chickens, revealing diverse functions such as immune response and metabolism. The findings suggest that infections with different Eimeria species elicit similar biological responses in chickens at the system level.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Food Science & Technology
Priyanka Ghosh, Tiyasa Dey, Romit Majumder, Madhuri Datta, Aindrila Chattopadhyay, Debasish Bandyopadhyay
Summary: This study investigated the protective effects of melatonin on liver and kidney tissues against chromium-induced oxidative damage in male Wistar rats. Melatonin preserved body weight, antioxidant enzymes, and tissue morphology, and reduced organ damage markers, oxidative stress-biomarkers, pro-oxidant enzymes, reactive oxygen species, nitric oxide, and collagen content. Melatonin also decreased tissue chromium content through its metal-chelating activity. These findings suggest that melatonin could be a promising therapeutic agent for preventing chromium-induced oxidative stress-mediated tissue damage.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
