Review
Plant Sciences
Wei Wu, Wenhua Chen, Shiyu Liu, Jianjun Wu, Yeting Zhu, Luping Qin, Bo Zhu
Summary: Endophytic bacteria play a crucial role in promoting plant growth, enhancing resistance to stresses, and regulating the synthesis of medicinal metabolites. Understanding their relationships with medicinal plants can lead to more effective applications in various industries.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Pharmacology & Pharmacy
A. Y. S. W. A. R. Y. A. Sreenivasan, R. Manikkam, K. Manigundan
Summary: The current study isolated endophytic actinobacteria from medicinal plants and explored their antimicrobial activity. One strain of Streptomyces sp. (named KCA1) exhibited the greatest zone of inhibition and antimicrobial metabolite production. Chromatography and mass spectroscopy analysis revealed the compounds responsible for its antimicrobial activity.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Food Science & Technology
Hakimeh Oloumi, Moj Khaleghi, Ava Dalvand
Summary: Plant biotechnology has facilitated the development of new products with enhanced disease resistance, drought and salt stress tolerance, and nutritional value. This study aimed to isolate endophytic Actinobacteria strains from medicinal plants and evaluate their bioactive potential. Fifteen Actinobacteria strains were isolated from Persian iris and Echium amoenum plants, which showed antioxidant activity. Phylogenetic analysis revealed that two strains belonged to the Streptomyces genus. Furthermore, the supernatant of a selected endophytic strain promoted root and shoot growth and increased chlorophyll content in wheat plants under salinity stress. Overall, symbiotic strains with medicinal plants are valuable sources of bioactive compounds.
FOOD SCIENCE & NUTRITION
(2023)
Review
Integrative & Complementary Medicine
Hao Da-Cheng, Hou Xu-Dong, Gu Xiao-Jie, Xiao Pei-Gen, Ge Guang-Bo
Summary: Cephalotaxus is the only genus of the Cephalotaxaceae family, and its natural resources are declining due to habitat fragmentation, excessive exploitation, and destruction. Traditional applications of Cephalotaxus plants for treating various diseases have been acknowledged, and efforts are being made to develop their phytometabolites into therapeutic drugs, particularly in the field of anticancer reagents. Research on the ethnopharmacology, chemodiversity, and bioactivities of Cephalotaxus medicinal plants is advancing, with a focus on identifying and utilizing their beneficial compounds. Future research directions should involve strengthening the application of advanced technologies and continuous efforts to collect and sort out folk medicinal knowledge related to Cephalotaxus.
CHINESE JOURNAL OF NATURAL MEDICINES
(2021)
Article
Multidisciplinary Sciences
Julia L. Camina, Virginia Usseglio, Victoria Marquez, Carolina Merlo, Jose S. Dambolena, Julio A. Zygadlo, Lorena Ashworth
Summary: Essential oils produced by medicinal plants have valuable bioactive properties. This study found that pollination and herbivory can modify the chemical composition of essential oils and influence their bioactivity. The outcrossed progeny had higher abundance of oxygenated terpenes and stronger bacteriostatic effect on Staphylococcus aureus compared to inbred progeny. The effects of herbivory on bioactivity are still unknown. This study highlights the importance of pollination quality (self vs. cross) in the ecosystem services related to the biological activity of plant essential oils.
SCIENTIFIC REPORTS
(2023)
Article
Plant Sciences
Magdalena Elizabeth Lang, Timothy Sibanda, Stefan Louw, Jean Damascene Uzabakiriho
Summary: This study isolated and characterized endophytic actinobacteria from the Kalahari Desert plant,Harpagophytum procumbens, and evaluated their antimicrobial activity and taxonomic diversity. The ethyl acetate fraction showed broad-spectrum antimicrobial activity, especially against gram-negative bacteria. Genetic analysis and gas chromatography-mass spectrometry revealed the presence of bioactive compounds. These findings suggest that endophytic actinobacteria from H. procumbens are diverse and have the potential to produce antimicrobial compounds.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Agronomy
Q. A. Tuan Vo, Ross A. Ballard, Stephen J. Barnett, Christopher M. M. Franco
Summary: Endophytic actinobacteria isolated from chickpea roots, such as Actinomadura sp. CP84B, Microbispora sp. CP56, and Streptomyces spp. CP21A2 and CP200B, have shown potential in promoting the growth and nodulation of chickpea plants.
Article
Biotechnology & Applied Microbiology
Aram R. Ali, Yadollah Bahrami, Elham Kakaei, Sara Mohammadzadeh, Sasan Bouk, Nastaran Jalilian
Summary: Antibiotic resistance is a global threat to human health, and the discovery of new antibiotics from unexplored habitats is crucial. This study isolated endophytic actinobacteria (EA) from the Citrullus colocynthis plant and investigated their antibacterial properties. Six endophytic actinobacteria were isolated, and they were classified into two families based on morphological features and molecular identification. One of the isolated strains was proposed as a novel species/strain. Five strains showed antagonistic activity against pathogenic bacteria, indicating the potential of Citrullus colocynthis as an untapped source for the discovery of new antibiotics.
MICROBIAL CELL FACTORIES
(2022)
Review
Microbiology
Augustin Ntemafack, Nitika Kapoor, Sabeena Ali, Vijay Lakshmi Jamwal, Qazi Parvaiz Hassan, Sumit G. Gandhi
Summary: Africa is home to a rich variety of medicinal plants, many of which have been scientifically proven for their medicinal values. However, the exploration of endophytes and their bioactive secondary metabolites from these plants is still limited.
CURRENT MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Aiping Yang, Yu Hong, Fengjuan Zhou, Ling Zhang, Youjuan Zhu, Chang Wang, Yang Hu, Li Yu, Lihong Chen, Xiachang Wang
Summary: One of the biggest concerns in global health today is antibiotic resistance, highlighting the need to find alternative solutions. This study focuses on investigating endophytic microorganisms from medicinal plants in Fenghuang Mountain in order to discover new antibiotics. The research demonstrates the potential of these microbes to produce a variety of natural products, making them an important source for new antibiotics.
Article
Environmental Sciences
Mauro Enrique Yarte, Maria Ines Gismondi, Berta Elizabet Llorente, Ezequiel Enrique Larraburu
Summary: Plant interactions with endophytic bacteria, specifically those isolated from Handroanthus impetiginosus, have been found to provide mutual benefits and promote environmental sustainability. In this study, native endophytic bacteria were isolated and characterized from pink lapacho trees. The majority of the isolated strains exhibited plant growth promoting traits, including nitrogen fixation, phosphate and zinc solubilization, and production of indole compounds. Additionally, these bacteria showed salt tolerance, suggesting their potential advantage in saline conditions. This research contributes to the understanding of plant-bacteria associations and has implications for the development of biofertilizers to reduce the dependence on chemical fertilizers and pesticides.
ENVIRONMENTAL TECHNOLOGY
(2022)
Review
Plant Sciences
Arpita Tripathi, Praveen Pandey, Shakti Nath Tripathi, Alok Kalra
Summary: Ensuring food and nutritional security is crucial in agriculture, but excessive use of chemicals has led to harmful effects on the environment. Upgrading farming systems towards the use of biological agents can maintain agricultural and environmental sustainability. Endophytic microorganisms play vital roles in plant growth and adaptability. Medicinal and aromatic plants are important worldwide, but they are vulnerable to pests and diseases. Therefore, harnessing endophytic microorganisms as biostimulants can effectively improve plant yield and health.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Sunithi Gunasekera, Sanjeevan Rajendran, Blazej Slazak, Supun Mohotti, Taj Muhammad, Malgorzata Kapusta, Adam A. Stroemstedt, Emilia Wilmowicz, Ulf Goeransson, Chamari M. Hettiarachchi
Summary: Cyclotides are structurally stable circular miniproteins of plant origin that have potential pharmaceutical and agricultural applications. In this study, new cyclotides were identified in Sri Lankan flora, particularly in Geophila repens, and were found to exhibit cytotoxic and antimicrobial activities. The localization of cyclotides in the epidermis of the leaves and petioles suggests their potential role as plant defense molecules. The presence of similar cytotoxic cyclotides in phylogenetically distant plants supports the idea of coevolution for host defense.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Food Science & Technology
Rafael Mascoloti Sprea, Cristina Caleja, Jose Pinela, Tiane C. Finimundy, Ricardo C. Calhelha, Marina Kostic, Marina Sokovic, Miguel A. Prieto, Eliana Pereira, Joana S. Amaral, Lillian Barros
Summary: Medicinal and aromatic plants (MAP) from the Lamiaceae family were screened for their potential as natural bioactive ingredients. The extracts showed promising antioxidant activity and inhibitory effects against bacteria and fungi associated with food hazards. These plants have the potential to be used in various industries, such as food and cosmetics.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Microbiology
Beatriz M. Assad, Daiani C. Savi, Stellee M. P. Biscaia, Barbara F. Mayrhofer, Jucelia Iantas, Mathias Mews, Jaqueline C. de Oliveira, Edvaldo S. Trindade, Chirlei Glienke
Summary: The study on the endophytic actinobacteria of the native plant Hymenachne amplexicaulis in the Pantanal wetland revealed the potential antibacterial and cytotoxic properties of these microorganisms. The results emphasize the importance of discovering new drugs and the urgent need to conserve ecosystems such as the Brazilian Pantanal.
MICROBIOLOGICAL RESEARCH
(2021)