4.0 Article

Fumaric acid, an antibacterial component of Aloe vera L.

Journal

AFRICAN JOURNAL OF BIOTECHNOLOGY
Volume 10, Issue 15, Pages 2973-2977

Publisher

ACADEMIC JOURNALS
DOI: 10.5897/ajb10.1497

Keywords

Fumaric acid; Aloe vera; antibacterial activity

Funding

  1. Jilin University
  2. National Key Technology R & D Program in the People's Republic of China [2008BADB4B04]

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The acetoacetate fraction partitioned from Aloe vera L. showed an effective antibacterial activity against four clinically frequent pathogenic bacteria. Through a series of chromatographic methods and activity assays, one compound was obtained and it has potent antibacterial activity. Based on the data of mass spectrometry, H-1-NMR, C-13-NMR and IR spectra, this compound was determined to be fumaric acid. This study concluded that fumaric acid is one of the antibacterial components in A. vera.

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