Article
Chemistry, Organic
Amreen Chouhan, Kusum Ucheniya, Lalit Yadav, Pooja Kumari Jat, Asha Gurjar, Satpal Singh Badsara
Summary: A sustainable electrochemical approach for site-selective C-H mono and bis-chalcogenation (sulfenylation or selenylation) of indolizine frameworks is described. Diversely functionalized disulfides and diselenides possessing EDGs and EWGs were successfully reacted with a variety of indolizines to directly access sulfenylated/selenylated indolizines in 40-96% yields. A mechanistic radical pathway was also validated with control experiments and cyclic voltammogram data.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Narendra R. Chaubey, Anant R. Kapdi
Summary: A new reaction methodology has been developed for the thio(hetero)arylation of imidazoheterocycles under metal and base-free conditions. This reaction allows for the synthesis of compounds with significant biological properties, by linking imidazopyridines with electron-deficient heteroarenes through a sulfur atom. The reaction conditions are well tolerated by a wide range of 2-chloroheteroarenes and imidazoheterocycles.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Tao Guo, Lei Bi, Lu Shen, Quanhong Wei, Congjun Zhu, Panke Zhang, Yunhui Zhao
Summary: This article presents a convenient and efficient method for oxidative sulfenylation at the beta-position of tetrahydroisoquinolines under KIO3 catalysis, followed by aromatization in the presence of elemental S-8 to produce a wide range of structurally diverse 4-sulfenylisoquinolines/3-sulfenylpiperidine with excellent functional group tolerance and high efficiency.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Organic
Shanping Chen, Zhuoqin Li, Kai Hu, Wei Feng, Guojiang Mao, Fuhong Xiao, Guo-Jun Deng
Summary: A three-component method using an iodine-containing reagent has been developed for the selective synthesis of phenothiazines and bis-phenothiazines. Starting from easily available cyclohexanones, elemental sulfur, and inorganic ammonium salts, this protocol selectively produces the desired compounds under aerobic conditions with satisfactory yields. This method offers a practical approach for the preparation of phenothiazines and bis-phenothiazines, utilizing readily available starting materials and metal-free conditions.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Engineering, Environmental
Jiahui Zou, Yan-Ying Qiu, Hao Li, Feng Jiang
Summary: This study proposed a novel chemoautotrophic elemental sulfur disproportionation (SD) process as an alternative to conventional biological sulfidogenic processes (BSPs) for the treatment of organic-deficit acid mine drainage (AMD). The SD process achieved a stable high-rate sulfide production without the need for exogenous organic substrates, and it effectively removed over 99% of the influent metals from AMD.
Review
Chemistry, Organic
Gabriel M. F. Batista, Pedro P. de Castro, Juliana A. dos Santos, Troels Skrydstrup, Giovanni W. Amarante
Summary: Thiols are known for their strong odor and high toxicity, making it highly desirable to develop thiol-free alternatives for constructing sulfur-containing derivatives, especially sulfides. In recent years, various approaches utilizing alternative sources have been described for the preparation of these compounds. This critical review provides an in-depth analysis of the preparation of these derivatives, including selected examples and mechanistic pathways.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Organic
Yong Yuan, Zhilin Zhou, Lin Zhang, Liang-Sen Li, Aiwen Lei
Summary: The electrochemical oxidative C3 acyloxylation of imidazo[1,2-alpha]pyridines was demonstrated for the first time, showing that it can be carried out under mild conditions and is applicable to alkyl carboxylic acids as well as aromatic carboxylic acids.
Article
Chemistry, Organic
Li-Sheng Wang, You Zhou, Shuang-Gui Lei, Xiao-Xiao Yu, Chun Huang, Yan-Dong Wu, An-Xin Wu
Summary: A novel multicomponent cascade reaction has been reported for the synthesis of imidazo[2,1-a]isoquinoline derivatives in one-pot via the construction of two C-N bonds and one C-S/C-Se bond. The reaction achieves simultaneous C(sp3)-H amination and sulfenylation/selenation, avoiding complicated substrate preparation. It has simple operating conditions and good substrate compatibility.
Article
Chemistry, Multidisciplinary
Jingwei Zhou, Songping Wang, Yaoming Lu, Lamei Li, Wentao Duan, Qi Wang, Hong Wang, Wentao Wei
Summary: A simple, practical, and environmentally friendly C(sp(3))-H thiocarbonylation method for benzylamine substrates has been developed without the need for a catalyst, enabling the facile synthesis of thioamides, with a diverse array of benzylamine derivatives being tolerated. The reaction mechanism involves specific solvents driving intermolecular hydrogen atom transfer (HAT) followed by single electron transfer (SET) to catalyze C-S bond formation and intramolecular HAT to establish the C=S bond.
Article
Engineering, Environmental
Junyuan Li, Kaisong Xiang, Cao Liu, Shudan He, Fenghua Shen, Hui Liu
Summary: Metal sulfides are promising sorbents for removing H-g(0) from flue gas, but they require regeneration. This study developed a CoS2 loaded porous carbon for H-g(0) capture and investigated the regeneration using elemental sulfur. Elemental sulfur effectively recovered the H-g(0) capture ability of the sorbent and showed similar regeneration stability compared to toxic H2S. The regenerated sorbent had higher S-2(2-) sites but less Co3+ and S-n(2-) (n >2) sites compared to the fresh sample.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Shanshan Wang, Yuemin Zhou, Yuqi Wang, Fuhao Dong, He Liu, Xu Xu
Summary: By using reverse vulcanization, the polyTA was stabilized with natural turpentine monomers (beta-pinene and limonene), resulting in transparent self-healing and antibacterial turpentine oil-modified polyTA (TA-beta and TA-LIM). TA-beta and TA-LIM exhibited favorable thermal stability, mechanical property, self-healing efficiency, and antibacterial capacity.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Wenjing Guan, Ke Ying, Chengcheng Yuan, Jinlin Hang, Chengkou Liu, Xiangxing Huang, Zheng Fang, Kai Guo
Summary: A new green synthesis method has been demonstrated in this study, which achieved the annulation of imidazo[1,2-a]pyridines with alkynes under metal- and exogenous oxidant-free conditions through electrochemical oxidation, resulting in the synthesis of polycyclic aromatic compounds.
Article
Chemistry, Organic
Juyeong Lee, Eunsoo Yu, Cheol-Min Park
Summary: A synthesis method of benzothiophenes through electrosynthesis under oxidant- and metal-free conditions has been discovered, which can efficiently produce benzothiophene compounds with good functional group tolerance.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Polymer Science
Liam J. Dodd, Cassio Lima, David Costa-Milan, Alex R. Neale, Benedict Saunders, Bowen Zhang, Andrei Sarua, Royston Goodacre, Laurence J. Hardwick, Martin Kuball, Tom Hasell
Summary: Inverse vulcanised polymers have been studied due to their easy and cheap synthesis from elemental sulfur, resulting in a wide range of valuable properties. However, the high sulfur content makes the polymers difficult to analyze. This study presents the use of Raman spectroscopy to better understand the structure and properties of these polymers. It was found that Raman spectroscopy can provide key information about the elemental sulfur content, homogeneity, reactions, and proportions of different sulfur ranks in the polymer.
Article
Polymer Science
Yusuke Onose, Yuri Ito, Junpei Kuwabara, Takaki Kanbara
Summary: This study aims to develop guidelines for monomer selection in inverse vulcanization. Various olefin monomers were inverse-vulcanized and their side reactions were traced. The results identified terminal structures caused by chain transfer and byproducts that contribute to polymer coloration. Evaluation of thermal stability showed different behaviors for polymers obtained from different types of olefin monomers, providing guidance for monomer selection.
Article
Chemistry, Applied
Jia-Hao Chen, Wasim Ahmed, Ming-Hua Li, Zhao-Dong Li, Zi-Ning Cui, Ri-Yuan Tang
ADVANCED SYNTHESIS & CATALYSIS
(2020)
Article
Chemistry, Organic
Zhu Zhu, Jinggong Liu, Shoucheng Dong, Bolai Chen, Zhenghui Wang, Ri-yuan Tang, Zhaodong Li
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Yong-Chao Gao, Zi-Hao Huang, Zhao-Sheng Zhang, Jin-Xin Xie, Zi-Ning Cui, Ri-Yuan Tang
SYNTHESIS-STUTTGART
(2020)
Article
Chemistry, Organic
Zhuoxian Shao, Shaoyi Zhang, Yihan Chen, Yun-Lin Liu, Ri-Yuan Tang, Zhaodong Li
Article
Chemistry, Organic
Zhuo-Bin Huang, Xue-Ying Guo, Zi-Hao Huang, Ming-Hua Li, Shou-Cheng Dong, Ri-Yuan Tang
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Jian-Xiong He, Huan-Yu Pan, Li Xu, Ri-Yuan Tang
Summary: Aflatoxins are highly toxic carcinogens, and molecular imprinting polymers have been widely applied for their detection and separation. Different polymerization methods and applications of molecular imprinting polymers in aflatoxin detection were reviewed in this study.
JOURNAL OF CHEMICAL RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Wasim Ahmed, Zi-Hao Huang, Zi-Ning Cui, Ri-Yuan Tang
Summary: This study reports the synthesis of unique mesoionic thiazoloisoquinolinium thiolates via cycloaddition reaction, which shows good bioactivity against the chlorophyll of duckweed.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Organic
Yiming Du, Shuxin Chen, Ao Huang, Yihan Chen, Yun-Lin Liu, Gaopeng Song, Ri-Yuan Tang, Hanhong Xu, Guangkai Yao, Zhaodong Li
Summary: This article reports a versatile and expeditious method for site-selective C-H fluoromethylation of aryl iodides via Pd/norbornene cooperative catalysis. It can serve as a robust toolbox for the diversity-oriented synthesis (DOS) of fluoromethylated arenes. The method features the use of low-cost industrial raw material CH2IF as the fluoromethyl source, excellent functional group tolerance, and broad ipso termination scope. It can also be applied to the late-stage modification of biorelevant molecules.
Article
Chemistry, Multidisciplinary
Shuxin Chen, Xue Liu, Kaidian Li, Wenchao Yang, Jian Lin, Ri-Yuan Tang, Hanhong Xu, Zhaodong Li
Summary: A novel approach based on Pd/norbornene cooperative catalysis is presented for the efficient assembly of beta-fluoroalkylated arenes. The method shows excellent functional group tolerance and a wide range of ipso termination reactions. Additionally, it enables the synthesis of diverse fluorinated macrolactones under mild reaction conditions, which is otherwise extremely challenging.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Chemistry, Medicinal
Jinxin Xie, Lijuan Wang, Xiaoyong Zhang, Yiyang Li, Xin Liao, Caixin Yang, Ri-Yuan Tang
Summary: Aryloxyethyl propiolates and their homologues are promising anti-MRSA agents with multiple targets, as they can destroy the cell wall and cell membrane, inhibit the formation of a biofilm, and bind to the DNA of MRSA.
ACS INFECTIOUS DISEASES
(2022)
Article
Chemistry, Applied
Guangkai Yao, Chuanle Zhu, Tianyi Qin, Mengfan Wang, Zhixiu Sun, Ri-Yuan Tang, Chen Zhao, Huanfeng Jiang, Hanhong Xu
Summary: The oxidative [3+2+1] annulation reaction of aldehydes, 5-aminopyrazoles, and nitriles under the oxidation of I-2/O-2 produces valuable pyrazolo[3,4-d]pyrimidines in yields of 27%-91%. This reaction is notable for being transition-metal free, operationally simple, having a broad substrate scope, good functional group tolerance, and being scalable.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Agriculture, Multidisciplinary
Zi-Hao Huang, Xue-Ying Guo, Lan-Tu Xiong, Li Dong, Jin-Tong Jian, Lin-Hao Wei, Ri-Yuan Tang, Han-Hong Xu
Summary: In this study, novel N-difluoromethyl triazole selenoureas have been developed as a versatile artificial organoselenides defense (AOSeD) for controlling pests, phytopathogenic fungi, and weeds. Furthermore, the AOSeD is safe for tomato plants and Brassica campestris.
ACS AGRICULTURAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Jinxin Xie, Benjian Liao, Hui Zhu, Yongfei Yu, Ri-Yuan Tang
Summary: The study synthesized novel 2-methyl-3-furyl sulfide flavor derivatives and evaluated their antimicrobial activity against foodborne bacteria and fungi. Fifteen compounds were found to have potential as preservatives for food production, with some showing better antimicrobial activity than traditional control groups.
Review
Agriculture, Multidisciplinary
Jinxin Xie, Benjian Liao, Ri-Yuan Tang
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2020)
Article
Chemistry, Organic
Zhuo-Bin Huang, Xiong-Jian Xia, Zi-Hao Huang, Li Xu, Xiao-Yong Zhang, Ri-Yuan Tang
ORGANIC & BIOMOLECULAR CHEMISTRY
(2020)
