Copper(I)/N-Heterocyclic Carbene (NHC)-Catalyzed Addition of Terminal Alkynes to Trifluoromethyl Ketones for Use in Continuous Reactors

A Continuous-Flow Process for the Synthesis of Artemisinin

(2013) Daniel Kopetzki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cooperative Catalysis of Metal and OH⋅⋅⋅O/sp3-CH⋅⋅⋅O Two-Point Hydrogen Bonds in Alcoholic Solvents: Cu-Catalyzed Enantioselective Direct Alkynylation of Aldehydes with Terminal Alkynes

(2013) Takaoki Ishii et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper N-heterocyclic carbene complexes in catalysis

(2013) Jonathan D. Egbert et al.   Catalysis Science & Technology

Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin

(2012) François Lévesque et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous Flow Synthesis. A Pharma Perspective

(2012) Laia Malet-Sanz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Autocatalysis Enables an Improved Synthesis of Efavirenz

(2011) Nicka Chinkov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

(2011) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Development of Catalytic Nucleophilic Additions of Terminal Alkynes in Water†

(2010) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

KMnO4-Mediated Oxidation as a Continuous Flow Process

(2010) Jörg Sedelmeier et al.   ORGANIC LETTERS

Cu(I)-Catalyzed Carboxylative Coupling of Terminal Alkynes, Allylic Chlorides, and CO2

(2010) Wen-Zhen Zhang et al.   ORGANIC LETTERS

Photodimerization of Maleic Anhydride in a Microreactor Without Clogging

(2010) Tomoaki Horie et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Copper- and copper-N-heterocyclic carbene-catalyzed CboxhH activating carboxylation of terminal alkynes with CO2 at ambient conditions

(2010) D. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

The Enantioselective Addition of Alkyne Nucleophiles to Carbonyl Groups

(2009) Barry M. Trost et al.   ADVANCED SYNTHESIS & CATALYSIS

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

(2009) Silvia Díez-González et al.   CHEMICAL REVIEWS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Addition of Terminal Alkynes to Aromatic Aldehydes Catalyzed by Copper(I) Complexes with Wide-Bite-Angle Chiral Bisphosphine Ligands: Optimization, Scope, and Mechanistic Studies

(2008) Yohsuke Asano et al.   ORGANOMETALLICS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS