4.7 Article

Palladium-Catalyzed Oxidative Intramolecular C-C Bond Formation via Double sp2 C-H Activation between the 2-Position of Imidazoles and a Benzene Ring

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 354, Issue 5, Pages 835-838

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201100801

Keywords

double sp2 C?H activation; imidazole- or benzimidazole-fused isoquinoline compounds; intramolecular C?C bond formation; palladium(II) catalysis

Funding

  1. Natural Science Foundation of China [21072168]

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Oxidative intramolecular C?C bond formation via double sp2 C?H activation between the 2-position of imidazoles and a benzene ring catalyzed by palladium(II) has been developed, which provides an atom-economical, concise and efficient methodology to synthesize imidazole- or benzimidazole-fused isoquinoline polyheteroaromatic compounds.

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