Transition Metal-Free α-C(sp3)H Bond Functionalization of Amines by Oxidative Cross Dehydrogenative Coupling Reaction: Simple and Direct Access to C-4-Alkylated 3,4-Dihydroquinazoline Derivatives

Carbon Nitride-Catalyzed Photoredox CC Bond Formation with N-Aryltetrahydroisoquinolines

(2012) Lennart Möhlmann et al.   ADVANCED SYNTHESIS & CATALYSIS

A Scalable, Efficient Gold-Catalyzed Oxidative Phosphonation of sp3 CH Bonds using Air as Sustainable Oxidant

(2012) Jin Xie et al.   ADVANCED SYNTHESIS & CATALYSIS

CDC Reactions of N-Aryl Tetrahydroisoquinolines Using Catalytic Amounts of DDQ: CH Activation under Aerobic Conditions

(2012) Kaliyamoorthy Alagiri et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Comparative Mechanistic Study of Cu-Catalyzed Oxidative Coupling Reactions with N-Phenyltetrahydroisoquinoline

(2012) Esther Boess et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 3H-Quinazolin-4-ones and 4H-3,1-Benzoxazin-4-ones via Benzylic Oxidation and Oxidative Dehydrogenation using Potassium Iodide-tert-Butyl Hydroperoxide

(2011) R. Arun Kumar et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Activation of a C sp 3H Bond Adjacent to a Nitrogen Atom: A Versatile Approach to Optically Active α-Alkyl α-Amino Acids and C1-Alkylated Tetrahydroisoquinoline Derivatives

(2011) Gen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Highly Efficient Gold-Catalyzed Oxidative CC Coupling from CH Bonds Using Air as Oxidant

(2011) Jin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo evaluation of oral anti-tumoral effect of 3,4-dihydroquinazoline derivative on solid tumor

(2011) Han Byul Kang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

An oxidative cross-dehydrogenative-coupling reaction in water using molecular oxygen as the oxidant: vanadium catalyzed indolation of tetrahydroisoquinolines

(2011) Kaliyamoorthy Alagiri et al.   CHEMICAL COMMUNICATIONS

Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions

(2011) Chao Liu et al.   CHEMICAL REVIEWS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Transition-metal catalyzed oxidative cross-coupling reactions to form C–C bonds involving organometallic reagents as nucleophiles

(2011) Wei Shi et al.   CHEMICAL SOCIETY REVIEWS

Iron-catalyzed Oxidative Coupling of Alkylamines with Arenes, Nitroalkanes, and 1,3-Dicarbonyl Compounds

(2011) Eiji Shirakawa et al.   CHEMISTRY LETTERS

Reactivity and Mechanistic Insight into Visible-Light-Induced Aerobic Cross-Dehydrogenative Coupling Reaction by Organophotocatalysts

(2011) Qiang Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dehydrogenative coupling reactions catalysed by Rose Bengal using visible light irradiation

(2011) Yuanhang Pan et al.   GREEN CHEMISTRY

Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography

(2011) Stephen Patterson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper-Catalyzed Oxidative Cross-Coupling ofN,N-Dimethylanilines with Heteroarenes under Molecular Oxygen

(2011) Lehao Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Studies on a Cu-Catalyzed Aerobic Oxidative Coupling Reaction withN-Phenyl Tetrahydroisoquinoline: Structure of Intermediates and the Role of Methanol As a Solvent

(2011) Esther Boess et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tropylium Ion Mediated α-Cyanation of Amines

(2011) Julia M. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H functionalization of tertiary amines by cross dehydrogenative coupling reactions: solvent-free synthesis of α-aminonitriles and β-nitroamines under aerobic condition

(2011) Kaliyamoorthy Alagiri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Functionally Diverse Nucleophilic Trapping of Iminium Intermediates Generated Utilizing Visible Light

(2011) David B. Freeman et al.   ORGANIC LETTERS

Eosin Y Catalyzed Visible Light Oxidative C–C and C–P bond Formation

(2011) Durga Prasad Hari et al.   ORGANIC LETTERS

New efficient synthesis of 2,3,4-trisubstituted 3,4-dihydroquinazolines by a Ugi 4CC/Staudinger/aza-Wittig sequence

(2011) Ying Zhong et al.   TETRAHEDRON

Highly Efficient One-Pot Synthesis of 2-Substituted Quinazolines and 4H-Benzo[d][1,3]oxazinesviaCross Dehydrogenative Coupling using Sodium Hypochlorite

(2010) C. Uma Maheswari et al.   ADVANCED SYNTHESIS & CATALYSIS

Cross-Dehydrogenative Coupling Reactions by Transition-Metal and Aminocatalysis for the Synthesis of Amino Acid Derivatives

(2010) Jin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antitumor activity of 3,4-dihydroquinazoline dihydrochloride in A549 xenograft nude mice

(2010) Soo Yeon Jung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Benzoyl peroxide (BPO)-promoted oxidative trifluoromethylation of tertiary amines with trimethyl(trifluoromethyl)silane

(2010) Lingling Chu et al.   CHEMICAL COMMUNICATIONS

Facile, solvent and ligand free iron catalyzed direct functionalization of N-protected tetrahydroisoquinolines and isochroman

(2010) Michael Ghobrial et al.   CHEMICAL COMMUNICATIONS

Gold-complexes catalyzed oxidative α-cyanation of tertiary amines

(2010) Yan Zhang et al.   CHEMICAL COMMUNICATIONS

Dual catalysis: combining photoredox and Lewis base catalysis for direct Mannich reactions

(2010) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

Direct C−H Transformation via Iron Catalysis

(2010) Chang-Liang Sun et al.   CHEMICAL REVIEWS

Beyond Traditional Cross Couplings: The Scope of the Cross Dehydrogenative Coupling Reaction

(2010) Caroline J. Scheuermann   Chemistry-An Asian Journal

A convenient synthesis of quinazoline derivatives via cascade imino-Diels-Alder and oxidation reaction

(2010) Xue Ming Chen et al.   CHINESE CHEMICAL LETTERS

FeCl3-Catalyzed Oxidative Allylation of sp2and sp3C−H Bond Adjacent to a Nitrogen Atom: Easy Access to Homoallyl Tertiary Amines

(2010) Gullapalli Kumaraswamy et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light Photoredox Catalysis: Aza-Henry Reactions via C−H Functionalization

(2010) Allison G. Condie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Platinum-catalyzed cross-dehydrogenative coupling reaction in the absence of oxidant

(2010) Xing-Zhong Shu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Unexpected synthesis of indolo[1,2-c]quinazolines by a sequential Ugi 4CC–Staudinger–aza-Wittig–nucleophilic addition reaction

(2010) Ping He et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Oxidative Coupling Reactions for the Formation of Carbon-Carbon Bonds without Carbon-Metal Intermediates

(2010) Martin Klussmann et al.   SYNTHESIS-STUTTGART

Selective Oxidation of Aromatic Amines to Nitro Derivatives using Potassium Iodide-tert-Butyl Hydroperoxide Catalytic System

(2009) K. Rajender Reddy et al.   ADVANCED SYNTHESIS & CATALYSIS

An efficient copper-catalyzed oxidative Mannich reaction between tertiary amines and methyl ketones

(2009) Youming Shen et al.   CHEMICAL COMMUNICATIONS

Selective Functionalization of sp3C−H Bonds Adjacent to Nitrogen Using (Diacetoxyiodo)benzene (DIB)

(2009) Xing-Zhong Shu et al.   JOURNAL OF ORGANIC CHEMISTRY

Site-specific C-functionalization of free-(NH) peptides and glycine derivatives via direct C-H bond functionalization

(2009) L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Facile synthesis of vicinal diamines via oxidation of N-phenyltetrahydroisoquinolines with DDQ

(2009) Althea S.-K. Tsang et al.   TETRAHEDRON LETTERS

Catalytic oxidative conversion of alcohols, aldehydes and amines into nitriles using KI/I2–TBHP system

(2009) K. Rajender Reddy et al.   TETRAHEDRON LETTERS

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Functionalizing Glycine Derivatives by Direct CC Bond Formation

(2008) Liang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1-Aryl-tetrahydroisoquinoline analogs as active anti-HIV agents in vitro

(2008) Pi Cheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

T-type Ca2+ channel blockers suppress the growth of human cancer cells

(2008) Jae Ho Heo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ruthenium catalyzed biomimetic oxidation in organic synthesis inspired by cytochrome P-450

(2008) Shun-Ichi Murahashi et al.   CHEMICAL SOCIETY REVIEWS

Oxidative Amidation of Aldehydes and Alcohols with Primary Amines Catalyzed by KI-TBHP

(2008) K. Rajender Reddy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Oxidative Cyanation of Tertiary Amines with Molecular Oxygen or Hydrogen Peroxide and Sodium Cyanide: sp3C−H Bond Activation and Carbon−Carbon Bond Formation

(2008) Shun-Ichi Murahashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY